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In the fields of biochemistry and pharmacology an allosteric regulator (or allosteric modulator) is a substance that binds to a site on an enzyme or receptor distinct from the active site, resulting in a conformational change that alters the protein's activity, either enhancing or inhibiting its function. In contrast, substances that bind directly to an…
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allosteric binding site substrate enzyme sites conformational allostery ligand active protein activity affinity also needed change orthosteric receptor citation subunits
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| Allosteric regulation | is a | dissociative concerted model.A morpheein is a homo-oligomeric structure that can exist as an ensemble of physiologically significant and functionally different alternate quatern… | 0.90 | text |
| Allosteric regulation | related to Allosteric Database | Allostery | 0.60 | section |
| Allosteric regulation | related to Allosteric Database | Due | 0.60 | section |
| Allosteric regulation | related to Allosteric Database | The AlloSteric Database | 0.60 | section |
| Allosteric regulation | related to Allosteric Database | ASD | 0.60 | section |
| Allosteric regulation | related to Allosteric Database | Currently | 0.60 | section |
| Allosteric regulation | related to Allosteric Database | Each | 0.60 | section |
| Allosteric regulation | related to Allosteric Database | Integrating | 0.60 | section |
| Allosteric regulation | related to Allosteric Database | In | 0.60 | section |
| Allosteric regulation | related to Allosteric residues and their prediction | Not | 0.60 | section |
| Allosteric regulation | related to Allosteric residues and their prediction | The | 0.60 | section |
| Allosteric regulation | related to Allosteric residues and their prediction | In | 0.60 | section |
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