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CDC37

Hsp90 co-chaperone Cdc37 is a protein that in humans is encoded by the CDC37 gene. This protein is highly similar to Cdc 37, a cell division cycle control protein of Saccharomyces cerevisiae. This protein is a HSP90 Co-chaperone with specific function in cell signal transduction. It has been shown to form complex with Hsp90 and a variety of protein…

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Aliases
CDC37, P50cell division cycle 37, cell division cycle 37, HSP90 cochaperone
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1US7, 2K5B, 2W0G, 2N5X, 2NCA, 5FWM, 5FWL, 5FWK
Band
19p13.2 · 9|9 A3
Bgee
sural nerve · apex of heart · granulocyte · body of uterus · left uterine tube
BioGPS
More reference expression data
Chr.
Chromosome 19 (human) · Chromosome 9 (mouse)

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CDC37

Nodes28
Edges27
Triples99
Avg. degree1.93
Density0.071429
Components1

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CDC37

Top relations

Gene ontology · 26
CDC37 → chaperone binding, chaperone complex, cytoplasm, cytosol, ERBB2 signaling pathway, extracellular exosome, heat shock protein binding, Hsp90 protein binding, HSP90-CDC37 chaperone complex, kinase binding, peptidyl-tyrosine phosphorylation, positive regulation of mitophagy in response to mitochondrial depolarization, posttranscriptional regulation of gene expression, protein binding, protein folding, protein kinase binding, protein kinase regulator activity, protein stabilization, protein targeting, protein tyrosine kinase activity
Bgee · 20
CDC37 → abdominal wall, apex of heart, body of uterus, canal of the cervix, dentate gyrus of hippocampal formation granule cell, efferent ductule, epiblast, gastric mucosa, granulocyte, left lobe of thyroid gland, left uterine tube, mandibular prominence, maxillary prominence, neural layer of retina, neural tube, right uterine tube, right ventricle, somite, sural nerve, upper lobe of left lung
RNA expression pattern · 20
CDC37 → abdominal wall, apex of heart, body of uterus, canal of the cervix, dentate gyrus of hippocampal formation granule cell, efferent ductule, epiblast, gastric mucosa, granulocyte, left lobe of thyroid gland, left uterine tube, mandibular prominence, maxillary prominence, neural layer of retina, neural tube, right uterine tube, right ventricle, somite, sural nerve, upper lobe of left lung
related to Domain architecture · 4
CDC37 → C-terminal, Hsp90, The, The N-terminal
related to Interactions · 3
CDC37 → CDK4, HSP90AA1IKBKG, IKK2
Band · 2
CDC37 → 19p13.2, 9|9 A3
Chr. · 2
CDC37 → Chromosome 19 (human), Chromosome 9 (mouse)
End · 2
CDC37 → 10,420,121 bp, 21,061,278 bp
related to External links · 2
CDC37 → Human CDC37, UCSC Genome Browser
Aliases · 1
CDC37 → CDC37, P50cell division cycle 37, cell division cycle 37, HSP90 cochaperone

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Important terminology

hsp90 protein bp human gene chr band cell chromosome 19 location kinases domain co-chaperone function mouse cdk4 37 division cycle

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
CDC37AliasesCDC37, P50cell division cycle 37, cell division cycle 37, HSP90 cochaperone1.00infobox
CDC37Available structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1US7, 2K5B, 2W0G, 2N5X, 2NCA, 5FWM, 5FWL, 5FWK1.00infobox
CDC37Band19p13.21.00infobox
CDC37Band9|9 A31.00infobox
CDC37Bgeesural nerve1.00infobox
CDC37Bgeeapex of heart1.00infobox
CDC37Bgeegranulocyte1.00infobox
CDC37Bgeebody of uterus1.00infobox
CDC37Bgeeleft uterine tube1.00infobox
CDC37Bgeeupper lobe of left lung1.00infobox
CDC37Bgeeleft lobe of thyroid gland1.00infobox
CDC37Bgeegastric mucosa1.00infobox
CDC37Bgeeright uterine tube1.00infobox
CDC37Bgeecanal of the cervix1.00infobox
CDC37Bgeemaxillary prominence1.00infobox
CDC37Bgeemandibular prominence1.00infobox
CDC37Bgeeright ventricle1.00infobox
CDC37Bgeeneural layer of retina1.00infobox
CDC37Bgeesomite1.00infobox
CDC37Bgeedentate gyrus of hippocampal formation granule cell1.00infobox
CDC37Bgeeepiblast1.00infobox
CDC37Bgeeabdominal wall1.00infobox
CDC37Bgeeefferent ductule1.00infobox
CDC37Bgeeneural tube1.00infobox
CDC37BioGPSMore reference expression data1.00infobox
CDC37Chr.Chromosome 19 (human)1.00infobox
CDC37Chr.Chromosome 9 (mouse)1.00infobox
CDC37DatabasesNCBI: entry; OMA: entry1.00infobox
CDC37End10,420,121 bp1.00infobox
CDC37End21,061,278 bp1.00infobox

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