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Hsp90 co-chaperone Cdc37 is a protein that in humans is encoded by the CDC37 gene. This protein is highly similar to Cdc 37, a cell division cycle control protein of Saccharomyces cerevisiae. This protein is a HSP90 Co-chaperone with specific function in cell signal transduction. It has been shown to form complex with Hsp90 and a variety of protein…
The analysis highlights Interactions, Overview and Domain architecture as prominent areas in the source structure around CDC37.
Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.
Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.
High-confidence facts extracted from structured source data. Use them as anchors for further research.
Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.
Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.
The extracted context around CDC37 shows recurring relationship patterns in the source. For example, CDC37 → chaperone binding, chaperone complex, cytoplasm, cytosol, ERBB2 signaling pathway, extracellular exosome, heat shock protein binding, Hsp90 protein binding, HSP90-CDC37 chaperone complex, kinase binding, peptidyl-tyrosine phosphorylation, positive regulation of mitophagy in response to mitochondrial depolarization, posttranscriptional regulation of gene expression, protein binding, protein folding, protein kinase binding, protein kinase regulator activity, protein stabilization, protein targeting, protein tyrosine kinase activity Another extracted example is CDC37 → abdominal wall, apex of heart, body of uterus, canal of the cervix, dentate gyrus of hippocampal formation granule cell, efferent ductule, epiblast, gastric mucosa, granulocyte, left lobe of thyroid gland, left uterine tube, mandibular prominence, maxillary prominence, neural layer of retina, neural tube, right uterine tube, right ventricle, somite, sural nerve, upper lobe of left lung. Use these groups to spot repeated connection types before inspecting the individual relationships.
Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.
hsp90 protein bp human gene chr band cell chromosome 19 location kinases domain co-chaperone function mouse cdk4 37 division cycle
TTTA extracted 99 structured relationships around CDC37. Examples in this analysis include CDC37 → Aliases → CDC37, P50cell division cycle 37, cell division cycle 37, HSP90 cochaperone and CDC37 → Available structures → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1US7, 2K5B, 2W0G, 2N5X, 2NCA, 5FWM, 5FWL, 5FWK. The table shows each extracted connection, where it came from and its confidence.
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| CDC37 | Aliases | CDC37, P50cell division cycle 37, cell division cycle 37, HSP90 cochaperone | 1.00 | infobox |
| CDC37 | Available structures | Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1US7, 2K5B, 2W0G, 2N5X, 2NCA, 5FWM, 5FWL, 5FWK | 1.00 | infobox |
| CDC37 | Band | 19p13.2 | 1.00 | infobox |
| CDC37 | Band | 9|9 A3 | 1.00 | infobox |
| CDC37 | Bgee | sural nerve | 1.00 | infobox |
| CDC37 | Bgee | apex of heart | 1.00 | infobox |
| CDC37 | Bgee | granulocyte | 1.00 | infobox |
| CDC37 | Bgee | body of uterus | 1.00 | infobox |
| CDC37 | Bgee | left uterine tube | 1.00 | infobox |
| CDC37 | Bgee | upper lobe of left lung | 1.00 | infobox |
| CDC37 | Bgee | left lobe of thyroid gland | 1.00 | infobox |
| CDC37 | Bgee | gastric mucosa | 1.00 | infobox |
| CDC37 | Bgee | right uterine tube | 1.00 | infobox |
| CDC37 | Bgee | canal of the cervix | 1.00 | infobox |
| CDC37 | Bgee | maxillary prominence | 1.00 | infobox |
| CDC37 | Bgee | mandibular prominence | 1.00 | infobox |
| CDC37 | Bgee | right ventricle | 1.00 | infobox |
| CDC37 | Bgee | neural layer of retina | 1.00 | infobox |
| CDC37 | Bgee | somite | 1.00 | infobox |
| CDC37 | Bgee | dentate gyrus of hippocampal formation granule cell | 1.00 | infobox |
| CDC37 | Bgee | epiblast | 1.00 | infobox |
| CDC37 | Bgee | abdominal wall | 1.00 | infobox |
| CDC37 | Bgee | efferent ductule | 1.00 | infobox |
| CDC37 | Bgee | neural tube | 1.00 | infobox |
| CDC37 | BioGPS | More reference expression data | 1.00 | infobox |
| CDC37 | Chr. | Chromosome 19 (human) | 1.00 | infobox |
| CDC37 | Chr. | Chromosome 9 (mouse) | 1.00 | infobox |
| CDC37 | Databases | NCBI: entry; OMA: entry | 1.00 | infobox |
| CDC37 | End | 10,420,121 bp | 1.00 | infobox |
| CDC37 | End | 21,061,278 bp | 1.00 | infobox |
The concept neighborhoods around CDC37 bring nearby vocabulary together. In this analysis, examples include Gene, Location and Human. Use the clusters to find adjacent concepts and terminology that may deserve separate research.
For CDC37, one of the stronger structural bridges in this analysis connects CDC37 with Overview. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.
TTTA analyzes the structure around CDC37 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Interactions, Overview & Domain architecture, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.
Source: Wikipedia — CDC37 · EN edition · Analysis: TopicsToTalkAbout