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LYK5: Function, Disease linkage & Interactions

Protein kinase LYK5, also known as LYK5 or STRADα, is a human protein and also denotes the gene encoding it.

Language: English [EN]
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LYK5 topic overview

The analysis highlights Function, Disease linkage and Interactions as prominent areas in the source structure around LYK5.

Related topics
12
Source areas
4
Connected nodes
16
Extracted relationships
95
Related term clusters
10
Bridge connections
16

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Function · 4 topics
Disease linkage · 3 topics
Interactions · 3 topics
Overview · 2 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases
STRADA, LYK5, NY-BR-96, PMSE, STRAD, Stlk, STE20-related kinase adaptor alpha, STRAD alpha, STE20 related adaptor alpha
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1UPK, 2WTK, 3GNI
Band
17q23.3 · 11|11 E1
Bgee
right uterine tube · gastric mucosa · left testis · right testis · tibial nerve
BioGPS
More reference expression data
Chr.
Chromosome 17 (human) · Chromosome 11 (mouse)

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Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Function

Disease linkage

Interactions

For the semantics nerds

You can skip this section if you’re here for content ideas and keyword inspiration.

Advanced semantic analysis

How LYK5 connects Entity context

The extracted context around LYK5 shows recurring relationship patterns in the source. For example, LYK5 → activation of protein kinase activity, ATP binding, cell cycle, cytoplasm, cytosol, kinase binding, MAPK cascade, neuron projection morphogenesis, nucleoplasm, nucleotide binding, nucleus, positive regulation of protein serine/threonine kinase activity, protein binding, protein export from nucleus, protein kinase activator activity, protein kinase activity, protein phosphorylation, protein serine/threonine kinase activator activity, protein serine/threonine kinase activity, regulation of apoptotic process Another extracted example is LYK5 → body of uterus, ganglionic eminence, gastric mucosa, granulocyte, left testis, morula, neural layer of retina, right frontal lobe, right hemisphere of cerebellum, right ovary, right testis, right uterine tube, seminiferous tubule, spermatid, spermatocyte, superior frontal gyrus, tail of embryo, tibial nerve, ventricular zone, zygote. Use these groups to spot repeated connection types before inspecting the individual relationships.

LYK5

Top relations

Gene ontology · 23
LYK5 → activation of protein kinase activity, ATP binding, cell cycle, cytoplasm, cytosol, kinase binding, MAPK cascade, neuron projection morphogenesis, nucleoplasm, nucleotide binding, nucleus, positive regulation of protein serine/threonine kinase activity, protein binding, protein export from nucleus, protein kinase activator activity, protein kinase activity, protein phosphorylation, protein serine/threonine kinase activator activity, protein serine/threonine kinase activity, regulation of apoptotic process
Bgee · 20
LYK5 → body of uterus, ganglionic eminence, gastric mucosa, granulocyte, left testis, morula, neural layer of retina, right frontal lobe, right hemisphere of cerebellum, right ovary, right testis, right uterine tube, seminiferous tubule, spermatid, spermatocyte, superior frontal gyrus, tail of embryo, tibial nerve, ventricular zone, zygote
RNA expression pattern · 20
LYK5 → body of uterus, ganglionic eminence, gastric mucosa, granulocyte, left testis, morula, neural layer of retina, right frontal lobe, right hemisphere of cerebellum, right ovary, right testis, right uterine tube, seminiferous tubule, spermatid, spermatocyte, superior frontal gyrus, tail of embryo, tibial nerve, ventricular zone, zygote
related to Function · 6
LYK5 → Endogenous LKB1, LKB1, LKB1-induced G1, Removal, RNA, STRADα
related to Disease linkage · 3
LYK5 → LYK5/STRADα, Mutations, PMSE
Band · 2
LYK5 → 11|11 E1, 17q23.3
Chr. · 2
LYK5 → Chromosome 11 (mouse), Chromosome 17 (human)
End · 2
LYK5 → 106,092,994 bp, 63,741,986 bp
Aliases · 1
LYK5 → STRADA, LYK5, NY-BR-96, PMSE, STRAD, Stlk, STE20-related kinase adaptor alpha, STRAD alpha, STE20 related adaptor alpha
Available structures · 1
LYK5 → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1UPK, 2WTK, 3GNI

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

human bp gene chr band stradα chromosome 17 kinase protein mouse location lkb1 strada function known search 741 986 end

LYK5 relationships Subject–Predicate–Object triples

TTTA extracted 95 structured relationships around LYK5. Examples in this analysis include LYK5 → Aliases → STRADA, LYK5, NY-BR-96, PMSE, STRAD, Stlk, STE20-related kinase adaptor alpha, STRAD alpha, STE20 related adaptor alpha and LYK5 → Available structures → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1UPK, 2WTK, 3GNI. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
LYK5AliasesSTRADA, LYK5, NY-BR-96, PMSE, STRAD, Stlk, STE20-related kinase adaptor alpha, STRAD alpha, STE20 related adaptor alpha1.00infobox
LYK5Available structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1UPK, 2WTK, 3GNI1.00infobox
LYK5Band17q23.31.00infobox
LYK5Band11|11 E11.00infobox
LYK5Bgeeright uterine tube1.00infobox
LYK5Bgeegastric mucosa1.00infobox
LYK5Bgeeleft testis1.00infobox
LYK5Bgeeright testis1.00infobox
LYK5Bgeetibial nerve1.00infobox
LYK5Bgeeright hemisphere of cerebellum1.00infobox
LYK5Bgeeright frontal lobe1.00infobox
LYK5Bgeeganglionic eminence1.00infobox
LYK5Bgeeright ovary1.00infobox
LYK5Bgeebody of uterus1.00infobox
LYK5Bgeespermatocyte1.00infobox
LYK5Bgeeseminiferous tubule1.00infobox
LYK5Bgeespermatid1.00infobox
LYK5Bgeeneural layer of retina1.00infobox
LYK5Bgeemorula1.00infobox
LYK5Bgeegranulocyte1.00infobox
LYK5Bgeetail of embryo1.00infobox
LYK5Bgeezygote1.00infobox
LYK5Bgeeventricular zone1.00infobox
LYK5Bgeesuperior frontal gyrus1.00infobox
LYK5BioGPSMore reference expression data1.00infobox
LYK5Chr.Chromosome 17 (human)1.00infobox
LYK5Chr.Chromosome 11 (mouse)1.00infobox
LYK5DatabasesNCBI: entry; OMA: entry1.00infobox
LYK5End63,741,986 bp1.00infobox
LYK5End106,092,994 bp1.00infobox

Related concept clusters Related term clusters

The concept neighborhoods around LYK5 bring nearby vocabulary together. In this analysis, examples include Gene, Known and Pmse. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • gene
    • Human
    • Kinase
    • Location
    • Chromosome
    • Lyk5
    • Bp
    • Chr
    • End
    • Function
    • Known
    • Pmse
    • Search
  • function
    • Search
    • Strada
    • Kinase
    • Location
    • Chromosome
    • Interactions
    • Linkage
    • Phosphorylation
    • Reading
    • References
    • Bp
    • Chr
  • LYK5
    • Gene
    • Known
    • Pmse
    • Human
    • Also
    • Denotes
    • Disease
    • Encoding
    • Interactions
    • Linkage
    • Reading
    • References
  • lyk5
    • Gene
    • Known
    • Pmse
    • Human
    • Also
    • Denotes
    • Disease
    • Encoding
    • Interactions
    • Linkage
    • Reading
    • References
  • protein
    • Lkb1
    • Mouse
    • Stradα
    • Denotes
    • Encoding
    • Gene
    • Human
    • Phosphorylation
    • End
    • Endogenous
    • Function
    • Rna
  • disease linkage
    • Interactions
    • Linkage
    • Reading
    • References
    • Function
    • Pmse
    • Search
    • Strada
    • Kinase
    • Location
    • Chromosome
    • Lyk5
  • lkb1
    • Mouse
    • Protein
    • Stradα
    • Phosphorylation
    • Rna
    • Search
    • Strada
    • Vivo
    • Location
  • interactions
    • Linkage
    • Reading
    • References
    • Pmse
    • Search
    • Strada
    • Kinase
    • Location
    • Lyk5

Connections between topic areas Semantic bridges

For LYK5, one of the stronger structural bridges in this analysis connects LYK5 with Function. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
LYK5 — Function · splits 12 ⟂ 5
LYK5 — Disease linkage · splits 13 ⟂ 4
LYK5 — Interactions · splits 13 ⟂ 4
LYK5 — Overview · splits 14 ⟂ 3

Map overview Semantic statistics

LYK5

Nodes17
Edges16
Triples95
Avg. degree1.88
Density0.117647
Components1

Source & methodology

TTTA analyzes the structure around LYK5 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Function, Disease linkage & Interactions, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — LYK5 · EN edition · Analysis: TopicsToTalkAbout

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