Research any topic before you write.

Find related topics. | Discover entities. | See connections. | Build a topical map.

NRF1

Nuclear respiratory factor 1, also known as Nrf1, Nrf-1, NRF1 and NRF-1, encodes a protein that homodimerizes and functions as a transcription factor which activates the expression of some key metabolic genes regulating cellular growth and nuclear genes required for respiration, heme biosynthesis, and mitochondrial DNA transcription and replication. The…

Function, Interactions & Overview

Use the mouse wheel or two fingers (on touchscreens) to zoom in and out of the map.

Research this topic

Explore the main themes, entities and connections around NRF1. Start with the topic map, then use the sections below for research and deeper semantic analysis.

Explore this topic

Start with a few of the strongest sections from the source topic. These are research directions, not a list of keywords you must use.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases
NRF1, ALPHA-PAL, nuclear respiratory factor 1
Band
7q32.2 · 6 A3.3|6 12.47 cM
Bgee
cerebellar hemisphere · right hemisphere of cerebellum · right uterine tube · ventricular zone · apex of heart
BioGPS
More reference expression data
Chr.
Chromosome 7 (human) · Chromosome 6 (mouse)
Databases
NCBI: entry; OMA: entry

Topics to explore

Browse the full topic structure. Each item opens a new analysis centered on that subject.

Overview

Function

Interactions

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

Map overview Semantic statistics

NRF1

Nodes29
Edges28
Triples88
Avg. degree1.93
Density0.068966
Components1

How this topic connects Entity context

See the strongest relationship patterns around the current topic before diving into the raw triples.

NRF1

Top relations

Gene ontology · 19
NRF1 → core promoter sequence-specific DNA binding, cytosol, DNA binding, DNA-binding transcription activator activity, RNA polymerase II-specific, DNA-binding transcription factor activity, extracellular exosome, generation of precursor metabolites and energy, mitochondrion organization, nucleoplasm, nucleus, positive regulation of transcription by RNA polymerase II, protein binding, protein homodimerization activity, regulation of transcription by RNA polymerase II, regulation of transcription, DNA-templated, RNA polymerase II cis-regulatory region sequence-specific DNA binding, RNA polymerase II core promoter sequence-specific DNA binding, transcription by RNA polymerase II, transcription, DNA-templated
Bgee · 18
NRF1 → anterior pituitary, apex of heart, cerebellar hemisphere, embryo, epiblast, ganglionic eminence, gastrocnemius muscle, granulocyte, Paneth cell, primary oocyte, right hemisphere of cerebellum, right uterine tube, Rostral migratory stream, secondary oocyte, sural nerve, thymus, ventricular zone, zygote
RNA expression pattern · 18
NRF1 → anterior pituitary, apex of heart, cerebellar hemisphere, embryo, epiblast, ganglionic eminence, gastrocnemius muscle, granulocyte, Paneth cell, primary oocyte, right hemisphere of cerebellum, right uterine tube, Rostral migratory stream, secondary oocyte, sural nerve, thymus, ventricular zone, zygote
related to External links · 6
NRF1 → FactorBookNrf1 This, Medicine, Medicine Medical Subject Headings, MeSH, National Library, United States National Library
related to Function · 4
NRF1 → COX, DNA, ETC, Nrf2
related to Interactions · 3
NRF1 → DYNLL1, PPARGC1A, PPRC1
Band · 2
NRF1 → 6 A3.3|6 12.47 cM, 7q32.2
Chr. · 2
NRF1 → Chromosome 6 (mouse), Chromosome 7 (human)
End · 2
NRF1 → 129,757,082 bp, 30,153,457 bp
Aliases · 1
NRF1 → NRF1, ALPHA-PAL, nuclear respiratory factor 1

Important terminology Word statistics

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

protein bp nuclear human factor chr band gene mitochondrial variants characterized chromosome expression dna transcription cellular regulation location function genes

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
NRF1AliasesNRF1, ALPHA-PAL, nuclear respiratory factor 11.00infobox
NRF1Band7q32.21.00infobox
NRF1Band6 A3.3|6 12.47 cM1.00infobox
NRF1Bgeecerebellar hemisphere1.00infobox
NRF1Bgeeright hemisphere of cerebellum1.00infobox
NRF1Bgeeright uterine tube1.00infobox
NRF1Bgeeventricular zone1.00infobox
NRF1Bgeeapex of heart1.00infobox
NRF1Bgeeanterior pituitary1.00infobox
NRF1Bgeegranulocyte1.00infobox
NRF1Bgeeganglionic eminence1.00infobox
NRF1Bgeesural nerve1.00infobox
NRF1Bgeegastrocnemius muscle1.00infobox
NRF1Bgeezygote1.00infobox
NRF1Bgeeprimary oocyte1.00infobox
NRF1Bgeesecondary oocyte1.00infobox
NRF1Bgeeepiblast1.00infobox
NRF1BgeeRostral migratory stream1.00infobox
NRF1BgeePaneth cell1.00infobox
NRF1Bgeethymus1.00infobox
NRF1Bgeeembryo1.00infobox
NRF1BioGPSMore reference expression data1.00infobox
NRF1Chr.Chromosome 7 (human)1.00infobox
NRF1Chr.Chromosome 6 (mouse)1.00infobox
NRF1DatabasesNCBI: entry; OMA: entry1.00infobox
NRF1End129,757,082 bp1.00infobox
NRF1End30,153,457 bp1.00infobox
NRF1EnsemblENSG000001064591.00infobox
NRF1Entrez48991.00infobox
NRF1External IDsOMIM: 600879; MGI: 1332235; GeneCards: NRF11.00infobox

Related concept clusters Concept neighborhoods

These clusters group vocabulary that occurs around closely connected concepts in the source material.

    Connections between topic areas Semantic bridges

    Bridges can reveal useful research angles that are easy to miss in a flat list of related terms.

    Min side: 3
    For writers, content strategists, SEOs, marketers and creators — from quick topic research to advanced semantic analysis.