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Acyl-CoA synthetase family member 3 (ACSF3) is a mitochondrial enzyme encoded by the ACSF3 gene. It is required for the degradation of malonic acid and methylmalonic acid and provides the precursor for mitochondrial fatty acid synthesis (mtFAS) and mitochondrial lysine malonylation. The enzyme belongs to the acyl-CoA synthetase family.
The analysis highlights Reaction, Function and Clinical significance as prominent areas in the source structure around ACSF3.
Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.
Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.
High-confidence facts extracted from structured source data. Use them as anchors for further research.
Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.
Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.
The extracted context around ACSF3 shows recurring relationship patterns in the source. For example, ACSF3 → appendix, bone marrow cell, brown adipose tissue, cardiac muscle tissue of left ventricle, corneal stroma, granulocyte, Ileal epithelium, interventricular septum, lactiferous gland, left adrenal cortex, left adrenal gland, left lobe of liver, mucosa of transverse colon, otic vesicle, proximal tubule, right adrenal cortex, right adrenal gland, right kidney, right lobe of liver, sural nerve Another extracted example is ACSF3 → acid-thiol ligase activity, ATP binding, catalytic activity, fatty acid biosynthetic process, fatty acid metabolic process, ligase activity, lipid metabolism, long-chain fatty-acyl-CoA biosynthetic process, malonate catabolic process, malonyl-CoA synthetase activity, metabolism, methylmalonyl-CoA synthetase activity, mitochondrial matrix, mitochondrion, nucleotide binding, protein malonylation, very long-chain fatty acid-CoA ligase activity. Use these groups to spot repeated connection types before inspecting the individual relationships.
Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.
acid mitochondrial malonyl-coa methylmalonic methylmalonyl-coa malonic lysine gene acyl-coa fatty synthesis malonate human malonylation activity bp metabolism mouse metabolic synthetase
TTTA extracted 158 structured relationships around ACSF3. Examples in this analysis include ACSF3 → 6.2.1.76 → ↗ and ACSF3 → Aliases → ACSF3, acyl-CoA synthetase family member 3. The table shows each extracted connection, where it came from and its confidence.
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| ACSF3 | 6.2.1.76 | ↗ | 1.00 | infobox |
| ACSF3 | Aliases | ACSF3, acyl-CoA synthetase family member 3 | 1.00 | infobox |
| ACSF3 | Band | 16q24.3 | 1.00 | infobox |
| ACSF3 | Band | 8|8 E1 | 1.00 | infobox |
| ACSF3 | Bgee | mucosa of transverse colon | 1.00 | infobox |
| ACSF3 | Bgee | granulocyte | 1.00 | infobox |
| ACSF3 | Bgee | right adrenal gland | 1.00 | infobox |
| ACSF3 | Bgee | sural nerve | 1.00 | infobox |
| ACSF3 | Bgee | bone marrow cell | 1.00 | infobox |
| ACSF3 | Bgee | right adrenal cortex | 1.00 | infobox |
| ACSF3 | Bgee | left adrenal gland | 1.00 | infobox |
| ACSF3 | Bgee | left adrenal cortex | 1.00 | infobox |
| ACSF3 | Bgee | right lobe of liver | 1.00 | infobox |
| ACSF3 | Bgee | appendix | 1.00 | infobox |
| ACSF3 | Bgee | Ileal epithelium | 1.00 | infobox |
| ACSF3 | Bgee | interventricular septum | 1.00 | infobox |
| ACSF3 | Bgee | cardiac muscle tissue of left ventricle | 1.00 | infobox |
| ACSF3 | Bgee | right kidney | 1.00 | infobox |
| ACSF3 | Bgee | lactiferous gland | 1.00 | infobox |
| ACSF3 | Bgee | corneal stroma | 1.00 | infobox |
| ACSF3 | Bgee | brown adipose tissue | 1.00 | infobox |
| ACSF3 | Bgee | otic vesicle | 1.00 | infobox |
| ACSF3 | Bgee | proximal tubule | 1.00 | infobox |
| ACSF3 | Bgee | left lobe of liver | 1.00 | infobox |
| ACSF3 | BioGPS | n/a | 1.00 | infobox |
| ACSF3 | Chr. | Chromosome 16 (human) | 1.00 | infobox |
| ACSF3 | Chr. | Chromosome 8 (mouse) | 1.00 | infobox |
| ACSF3 | Databases | NCBI: entry; OMA: entry | 1.00 | infobox |
| ACSF3 | End | 89,164,121 bp | 1.00 | infobox |
| ACSF3 | End | 122,817,880 bp | 1.00 | infobox |
The concept neighborhoods around ACSF3 bring nearby vocabulary together. In this analysis, examples include Malonyl-coa, Mitochondrial and Acid. Use the clusters to find adjacent concepts and terminology that may deserve separate research.
For ACSF3, one of the stronger structural bridges in this analysis connects ACSF3 with Overview. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.
TTTA analyzes the structure around ACSF3 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Reaction, Function & Clinical significance, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.
Source: Wikipedia — ACSF3 · EN edition · Analysis: TopicsToTalkAbout