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F-box/WD repeat-containing protein 7 is a protein that in humans is encoded by the FBXW7 gene.
The analysis highlights Function, Interactions and Overview as prominent areas in the source structure around FBXW7.
Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.
Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.
High-confidence facts extracted from structured source data. Use them as anchors for further research.
Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.
Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.
The extracted context around FBXW7 shows recurring relationship patterns in the source. For example, FBXW7 → cellular response to DNA damage stimulus, cellular response to UV, cyclin binding, cytoplasm, cytosol, endoplasmic reticulum, Golgi apparatus, identical protein binding, lipid homeostasis, lung development, mitochondrion, negative regulation of DNA endoreduplication, negative regulation of gene expression, negative regulation of hepatocyte proliferation, negative regulation of Notch signaling pathway, negative regulation of osteoclast development, negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding, negative regulation of SREBP signaling pathway, negative regulation of triglyceride biosynthetic process, Notch signaling pathway Another extracted example is FBXW7 → AML, C/EBPα, Despite, F-box, Fbls, Fbws, FBX30, Fbxs, FBXW7-mediated, For, IκBd, Mono-allelic, Myc, NF-κB, Notch1, One, Other, SCFs, SKP1-cullin-F-box, T-ALL. Use these groups to spot repeated connection types before inspecting the individual relationships.
Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.
gene bp human protein f-box chr band chromosome location function mouse ligase cell wd cancers encoded search 536 092 end
TTTA extracted 148 structured relationships around FBXW7. Examples in this analysis include FBXW7 → Aliases → FBXW7, AGO, CDC4, FBW6, FBW7, FBX30, FBXO30, FBXW6, SEL-10, SEL10, hAgo, hCdc4, F-box and WD repeat domain containing 7 and FBXW7 → Available structures → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2OVP, 2OVQ, 2OVR, 5IBK. The table shows each extracted connection, where it came from and its confidence.
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| FBXW7 | Aliases | FBXW7, AGO, CDC4, FBW6, FBW7, FBX30, FBXO30, FBXW6, SEL-10, SEL10, hAgo, hCdc4, F-box and WD repeat domain containing 7 | 1.00 | infobox |
| FBXW7 | Available structures | Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2OVP, 2OVQ, 2OVR, 5IBK | 1.00 | infobox |
| FBXW7 | Band | 4q31.3 | 1.00 | infobox |
| FBXW7 | Band | 3 F1|3 37.7 cM | 1.00 | infobox |
| FBXW7 | Bgee | Brodmann area 23 | 1.00 | infobox |
| FBXW7 | Bgee | Achilles tendon | 1.00 | infobox |
| FBXW7 | Bgee | epithelium of colon | 1.00 | infobox |
| FBXW7 | Bgee | middle temporal gyrus | 1.00 | infobox |
| FBXW7 | Bgee | superior frontal gyrus | 1.00 | infobox |
| FBXW7 | Bgee | occipital lobe | 1.00 | infobox |
| FBXW7 | Bgee | pons | 1.00 | infobox |
| FBXW7 | Bgee | parietal lobe | 1.00 | infobox |
| FBXW7 | Bgee | primary visual cortex | 1.00 | infobox |
| FBXW7 | Bgee | postcentral gyrus | 1.00 | infobox |
| FBXW7 | Bgee | prefrontal cortex | 1.00 | infobox |
| FBXW7 | Bgee | primary motor cortex | 1.00 | infobox |
| FBXW7 | Bgee | barrel cortex | 1.00 | infobox |
| FBXW7 | Bgee | visual cortex | 1.00 | infobox |
| FBXW7 | Bgee | temporal lobe | 1.00 | infobox |
| FBXW7 | Bgee | amygdala | 1.00 | infobox |
| FBXW7 | Bgee | saccule | 1.00 | infobox |
| FBXW7 | Bgee | Region I of hippocampus proper | 1.00 | infobox |
| FBXW7 | BioGPS | More reference expression data | 1.00 | infobox |
| FBXW7 | Chr. | Chromosome 4 (human) | 1.00 | infobox |
| FBXW7 | Chr. | Chromosome 3 (mouse) | 1.00 | infobox |
| FBXW7 | Databases | NCBI: entry; OMA: entry | 1.00 | infobox |
| FBXW7 | End | 152,536,092 bp | 1.00 | infobox |
| FBXW7 | End | 84,886,505 bp | 1.00 | infobox |
| FBXW7 | Ensembl | ENSG00000109670 | 1.00 | infobox |
| FBXW7 | Entrez | 55294 | 1.00 | infobox |
The concept neighborhoods around FBXW7 bring nearby vocabulary together. In this analysis, examples include Search, Signaling and Stabilization. Use the clusters to find adjacent concepts and terminology that may deserve separate research.
For FBXW7, one of the stronger structural bridges in this analysis connects FBXW7 with Function. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.
TTTA analyzes the structure around FBXW7 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Function, Interactions & Overview, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.
Source: Wikipedia — FBXW7 · EN edition · Analysis: TopicsToTalkAbout