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Estrogen-related receptor beta: Function & Overview

Estrogen-related receptor beta (ERR-β), also known as ESRRB or NR3B2 (nuclear receptor subfamily 3, group B, member 2), is a nuclear receptor that in humans is encoded by the ESRRB (Estrogen Related Receptor Beta) gene.

Language: English [EN]
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Estrogen-related receptor beta topic overview

The analysis highlights Function and Overview as prominent areas in the source structure around Estrogen-related receptor beta.

Related topics
4
Source areas
2
Connected nodes
6
Extracted relationships
109
Related term clusters
5
Bridge connections
6

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Function · 2 topics
Overview · 2 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases
ESRRB, DFNB35, ERR2, ERRb, ESRL2, NR3B2, estrogen related receptor beta, ERRbeta2, ERR beta-2, Esrrb
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1LO1
Band
14q24.3 · 12 D2|12 40.49 cM
Bgee
testicle · human kidney · muscle of thigh · apex of heart · gastrocnemius muscle
BioGPS
n/a
Chr.
Chromosome 14 (human) · Chromosome 12 (mouse)

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Estrogen-related receptor beta
4Nuclear receptor · Gene · Cell potency

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Function

For the semantics nerds

You can skip this section if you’re here for content ideas and keyword inspiration.

Advanced semantic analysis

How Estrogen-related receptor beta connects Entity context

The extracted context around Estrogen-related receptor beta shows recurring relationship patterns in the source. For example, Estrogen-related receptor beta → cell dedifferentiation, cell population proliferation, chromosome, cis-regulatory region sequence-specific DNA binding, condensed chromosome, cytoplasm, DNA binding, DNA-binding transcription activator activity, RNA polymerase II-specific, DNA-binding transcription factor activity, DNA-binding transcription factor activity, RNA polymerase II-specific, embryonic placenta development, inner ear development, integrator complex, intracellular receptor signaling pathway, metal ion binding, negative regulation of stem cell differentiation, negative regulation of transcription by RNA polymerase II, nuclear receptor activity, nucleoplasm, nucleus Another extracted example is Estrogen-related receptor beta → apex of heart, blastocyst, body of stomach, chorion, gastrocnemius muscle, human kidney, left ventricle, lumbar subsegment of spinal cord, morula, muscle of thigh, neural layer of retina, ooblast, renal medulla, retinal pigment epithelium, right auricle of heart, secondary oocyte, skeletal muscle tissue, stria vascularis, testicle, vestibular sensory epithelium. Use these groups to spot repeated connection types before inspecting the individual relationships.

Estrogen-related receptor beta

Top relations

Gene ontology · 46
Estrogen-related receptor beta → cell dedifferentiation, cell population proliferation, chromosome, cis-regulatory region sequence-specific DNA binding, condensed chromosome, cytoplasm, DNA binding, DNA-binding transcription activator activity, RNA polymerase II-specific, DNA-binding transcription factor activity, DNA-binding transcription factor activity, RNA polymerase II-specific, embryonic placenta development, inner ear development, integrator complex, intracellular receptor signaling pathway, metal ion binding, negative regulation of stem cell differentiation, negative regulation of transcription by RNA polymerase II, nuclear receptor activity, nucleoplasm, nucleus
Bgee · 20
Estrogen-related receptor beta → apex of heart, blastocyst, body of stomach, chorion, gastrocnemius muscle, human kidney, left ventricle, lumbar subsegment of spinal cord, morula, muscle of thigh, neural layer of retina, ooblast, renal medulla, retinal pigment epithelium, right auricle of heart, secondary oocyte, skeletal muscle tissue, stria vascularis, testicle, vestibular sensory epithelium
RNA expression pattern · 20
Estrogen-related receptor beta → apex of heart, blastocyst, body of stomach, chorion, gastrocnemius muscle, human kidney, left ventricle, lumbar subsegment of spinal cord, morula, muscle of thigh, neural layer of retina, ooblast, renal medulla, retinal pigment epithelium, right auricle of heart, secondary oocyte, skeletal muscle tissue, stria vascularis, testicle, vestibular sensory epithelium
Band · 2
Estrogen-related receptor beta → 12 D2|12 40.49 cM, 14q24.3
Chr. · 2
Estrogen-related receptor beta → Chromosome 12 (mouse), Chromosome 14 (human)
End · 2
Estrogen-related receptor beta → 76,501,837 bp, 86,568,402 bp
Aliases · 1
Estrogen-related receptor beta → ESRRB, DFNB35, ERR2, ERRb, ESRL2, NR3B2, estrogen related receptor beta, ERRbeta2, ERR beta-2, Esrrb
Available structures · 1
Estrogen-related receptor beta → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1LO1
BioGPS · 1
Estrogen-related receptor beta → n/a
Databases · 1
Estrogen-related receptor beta → NCBI: entry; OMA: entry

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

bp chr human chromosome band gene esrrb 14 receptor location mouse beta nr3b2 nuclear estrogen related function search 501 837

Estrogen-related receptor beta relationships Subject–Predicate–Object triples

TTTA extracted 109 structured relationships around Estrogen-related receptor beta. Examples in this analysis include Estrogen-related receptor beta → Aliases → ESRRB, DFNB35, ERR2, ERRb, ESRL2, NR3B2, estrogen related receptor beta, ERRbeta2, ERR beta-2, Esrrb and Estrogen-related receptor beta → Available structures → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1LO1. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
Estrogen-related receptor betaAliasesESRRB, DFNB35, ERR2, ERRb, ESRL2, NR3B2, estrogen related receptor beta, ERRbeta2, ERR beta-2, Esrrb1.00infobox
Estrogen-related receptor betaAvailable structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1LO11.00infobox
Estrogen-related receptor betaBand14q24.31.00infobox
Estrogen-related receptor betaBand12 D2|12 40.49 cM1.00infobox
Estrogen-related receptor betaBgeetesticle1.00infobox
Estrogen-related receptor betaBgeehuman kidney1.00infobox
Estrogen-related receptor betaBgeemuscle of thigh1.00infobox
Estrogen-related receptor betaBgeeapex of heart1.00infobox
Estrogen-related receptor betaBgeegastrocnemius muscle1.00infobox
Estrogen-related receptor betaBgeeleft ventricle1.00infobox
Estrogen-related receptor betaBgeerenal medulla1.00infobox
Estrogen-related receptor betaBgeebody of stomach1.00infobox
Estrogen-related receptor betaBgeeright auricle of heart1.00infobox
Estrogen-related receptor betaBgeeskeletal muscle tissue1.00infobox
Estrogen-related receptor betaBgeeneural layer of retina1.00infobox
Estrogen-related receptor betaBgeestria vascularis1.00infobox
Estrogen-related receptor betaBgeechorion1.00infobox
Estrogen-related receptor betaBgeeretinal pigment epithelium1.00infobox
Estrogen-related receptor betaBgeevestibular sensory epithelium1.00infobox
Estrogen-related receptor betaBgeemorula1.00infobox
Estrogen-related receptor betaBgeelumbar subsegment of spinal cord1.00infobox
Estrogen-related receptor betaBgeeblastocyst1.00infobox
Estrogen-related receptor betaBgeesecondary oocyte1.00infobox
Estrogen-related receptor betaBgeeooblast1.00infobox
Estrogen-related receptor betaBioGPSn/a1.00infobox
Estrogen-related receptor betaChr.Chromosome 14 (human)1.00infobox
Estrogen-related receptor betaChr.Chromosome 12 (mouse)1.00infobox
Estrogen-related receptor betaDatabasesNCBI: entry; OMA: entry1.00infobox
Estrogen-related receptor betaEnd76,501,837 bp1.00infobox
Estrogen-related receptor betaEnd86,568,402 bp1.00infobox

Related concept clusters Related term clusters

The concept neighborhoods around Estrogen-related receptor beta bring nearby vocabulary together. In this analysis, examples include Also, Encoded and Err-β. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • Estrogen-related receptor beta
    • Also
    • Encoded
    • Err-β
    • Group
    • Humans
    • Known
    • Member
    • Subfamily
    • Function
    • Search
    • Beta
    • Estrogen
  • estrogen-related receptor beta
    • Also
    • Encoded
    • Err-β
    • Estrogen
    • Group
    • Humans
    • Known
    • Member
    • Nr3b2
    • Related
    • Subfamily
    • Gene
  • gene
    • Location
    • Receptor
    • Chromosome
    • Human
    • Bp
    • Chr
    • D2
    • End
    • Function
    • Mouse
    • Nr3b2
    • Nuclear
  • nuclear receptor
    • Gene
    • Function
    • Receptor
    • Related
    • Search
    • Expression
    • Group
    • Humans
    • Location
    • Member
    • Subfamily
    • Transition
  • function
    • Search
    • Location
    • Receptor
    • Chromosome
    • Expression
    • Gene
    • Human
    • References
    • Transition
    • Bp
    • Chr
    • D2

Connections between topic areas Semantic bridges

For Estrogen-related receptor beta, one of the stronger structural bridges in this analysis connects Estrogen-related receptor beta with Overview. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
Estrogen-related receptor beta — Overview · splits 4 ⟂ 3
Estrogen-related receptor beta — Function · splits 4 ⟂ 3

Map overview Semantic statistics

Estrogen-related receptor beta

Nodes7
Edges6
Triples109
Avg. degree1.71
Density0.285714
Components1

Source & methodology

TTTA analyzes the structure around Estrogen-related receptor beta to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Function & Overview, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — Estrogen-related receptor beta · EN edition · Analysis: TopicsToTalkAbout

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