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GTPase HRas, also known as the "Harvey Rat sarcoma viral oncogene homolog" and transforming protein p21, is an enzyme that is encoded by the HRAS gene in humans. The HRAS gene is located on the short (p) arm of chromosome 11 at position 15.5, from base pair 522,241 to base pair 525,549. HRas is a small G protein in the Ras subfamily of the Ras…
The analysis highlights Function, Clinical significance and Overview as prominent areas in the source structure around HRAS.
Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.
Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.
High-confidence facts extracted from structured source data. Use them as anchors for further research.
Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.
Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.
The extracted context around HRAS shows recurring relationship patterns in the source. For example, HRAS → animal organ morphogenesis, apoptotic process, cell population proliferation, cell surface receptor signaling pathway, cellular response to gamma radiation, cellular senescence, chemotaxis, cytoplasm, cytosol, defense response to protozoan, endocytosis, ephrin receptor signaling pathway, GDP binding, glutamatergic synapse, Golgi apparatus, Golgi membrane, GTP binding, GTPase activity, intracellular membrane-bounded organelle, intrinsic apoptotic signaling pathway Another extracted example is HRAS → C-terminus, GAP, GDP, GEF, Growth, GTP, GTPase, GTPase HRas, GTPase-activating, HRAS-GTP, KRAS, NRAS, Once, PI, Raf, Ras, RasGAP, SOS1, Subsequently, The. Use these groups to spot repeated connection types before inspecting the individual relationships.
Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.
gene mutations protein cell cellular virus bp human chromosome 11 gtpase chr band oncogene cells growth costello syndrome cancer harvey
TTTA extracted 185 structured relationships around HRAS. Examples in this analysis include HRAS → 3.6.5.2 → ↗ and HRAS → Aliases → HRAS, C-BAS/HAS, C-H-RAS, C-HA-RAS1, CTLO, H-RASIDX, HAMSV, HRAS1, RASH1, p21ras, Harvey rat sarcoma viral oncogene homolog, HRas proto-oncogene, GTPase, RASK2. The table shows each extracted connection, where it came from and its confidence.
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| HRAS | 3.6.5.2 | ↗ | 1.00 | infobox |
| HRAS | Aliases | HRAS, C-BAS/HAS, C-H-RAS, C-HA-RAS1, CTLO, H-RASIDX, HAMSV, HRAS1, RASH1, p21ras, Harvey rat sarcoma viral oncogene homolog, HRas proto-oncogene, GTPase, RASK2 | 1.00 | infobox |
| HRAS | Available structures | Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes121P, 1AA9, 1AGP, 1BKD, 1CLU, 1CRP, 1CRQ, 1CRR, 1CTQ, 1GNP, 1GNQ, 1GNR, 1HE8, 1IAQ, 1IOZ, 1JAH, 1JAI, 1K8R,… | 1.00 | infobox |
| HRAS | Band | 11p15.5 | 1.00 | infobox |
| HRAS | Band | 7 F5|7 86.48 cM | 1.00 | infobox |
| HRAS | Bgee | skin of abdomen | 1.00 | infobox |
| HRAS | Bgee | skin of leg | 1.00 | infobox |
| HRAS | Bgee | putamen | 1.00 | infobox |
| HRAS | Bgee | caudate nucleus | 1.00 | infobox |
| HRAS | Bgee | nucleus accumbens | 1.00 | infobox |
| HRAS | Bgee | hypothalamus | 1.00 | infobox |
| HRAS | Bgee | temporal lobe | 1.00 | infobox |
| HRAS | Bgee | amygdala | 1.00 | infobox |
| HRAS | Bgee | right hemisphere of cerebellum | 1.00 | infobox |
| HRAS | Bgee | substantia nigra | 1.00 | infobox |
| HRAS | Bgee | dentate gyrus of hippocampal formation granule cell | 1.00 | infobox |
| HRAS | Bgee | lip | 1.00 | infobox |
| HRAS | Bgee | molar | 1.00 | infobox |
| HRAS | Bgee | superior frontal gyrus | 1.00 | infobox |
| HRAS | Bgee | esophagus | 1.00 | infobox |
| HRAS | Bgee | fetal liver hematopoietic progenitor cell | 1.00 | infobox |
| HRAS | Bgee | yolk sac | 1.00 | infobox |
| HRAS | Bgee | entorhinal cortex | 1.00 | infobox |
| HRAS | Bgee | perirhinal cortex | 1.00 | infobox |
| HRAS | Bgee | muscle of thigh | 1.00 | infobox |
| HRAS | BioGPS | More reference expression data | 1.00 | infobox |
| HRAS | Chr. | Chromosome 11 (human) | 1.00 | infobox |
| HRAS | Chr. | Chromosome 7 (mouse) | 1.00 | infobox |
| HRAS | Databases | NCBI: entry; OMA: entry | 1.00 | infobox |
| HRAS | End | 537,321 bp | 1.00 | infobox |
The concept neighborhoods around HRAS bring nearby vocabulary together. In this analysis, examples include Protein, Mutations and Cancer. Use the clusters to find adjacent concepts and terminology that may deserve separate research.
For HRAS, one of the stronger structural bridges in this analysis connects HRAS with Overview. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.
TTTA analyzes the structure around HRAS to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Function, Clinical significance & Overview, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.
Source: Wikipedia — HRAS · EN edition · Analysis: TopicsToTalkAbout