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Research this topic
Explore the main themes, entities and connections around HRAS. Start with the topic map, then use the sections below for research and deeper semantic analysis.
Explore this topic
Start with a few of the strongest sections from the source topic. These are research directions, not a list of keywords you must use.
Function
16 related topics
Clinical significance
10 related topics
Overview
18 related topics
Key facts & relationships
High-confidence facts extracted from structured source data. Use them as anchors for further research.
- 3.6.5.2
- ↗
- Aliases
- HRAS, C-BAS/HAS, C-H-RAS, C-HA-RAS1, CTLO, H-RASIDX, HAMSV, HRAS1, RASH1, p21ras, Harvey rat sarcoma viral oncogene homolog, HRas proto-oncogene, GTPase, RASK2
- Available structures
- Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes121P, 1AA9, 1AGP, 1BKD, 1CLU, 1CRP, 1CRQ, 1CRR, 1CTQ, 1GNP, 1GNQ, 1GNR, 1HE8, 1IAQ, 1IOZ, 1JAH, 1JAI, 1K8R,…
- Band
- 11p15.5 · 7 F5|7 86.48 cM
- Bgee
- skin of abdomen · skin of leg · putamen · caudate nucleus · nucleus accumbens
- BioGPS
- More reference expression data
Topics to explore
A structured outline of related entities, concepts and subtopics. Open any item to build a new map centered on it.Browse the full topic structure. Each item opens a new analysis centered on that subject.
Overview
- Enzyme
- Gene
- Chromosome 11 Chromosome 11 (human)
- Base pair
- Small G protein
- Ras subfamily
- Ras superfamily
- Small GTPases Small GTPase
- Guanosine triphosphate
- Raf kinase
- C-Raf
- MAPK/ERK pathway
- Oncogene
- Gammaretrovirus
- Evolutionary history History of life
- Oncovirus
- Retroviruses Retrovirus
- Proto-oncogene
Function
- Growth factor
- Growth factors
- Receptors Receptor (biochemistry)
- Cytoplasm
- GTPase
- Cell membranes
- Isoprenyl
- C-terminus
- PI 3-kinase
- GDP Guanosine diphosphate
- RasGAP
- SOS1
- Cytosol
- Ras Ras (protein)
- KRAS
- NRAS Neuroblastoma RAS viral oncogene homolog
Clinical significance
Advanced semantic analysis
Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.
Map overview Semantic statistics
Number of nodes, edges, triples, density and central hubs. Use it to gauge the size and connectivity of the map.HRAS
Nodes48
Edges47
Triples185
Avg. degree1.96
Density0.041667
Components1
How this topic connects Entity context
Quick relationship hints grouped by predicate. Useful for spotting recurring semantic connections around the current entity.See the strongest relationship patterns around the current topic before diving into the raw triples.
HRAS
Top relations
Gene ontology · 63
HRAS → animal organ morphogenesis, apoptotic process, cell population proliferation, cell surface receptor signaling pathway, cellular response to gamma radiation, cellular senescence, chemotaxis, cytoplasm, cytosol, defense response to protozoan, endocytosis, ephrin receptor signaling pathway, GDP binding, glutamatergic synapse, Golgi apparatus, Golgi membrane, GTP binding, GTPase activity, intracellular membrane-bounded organelle, intrinsic apoptotic signaling pathway
related to Function · 23
HRAS → C-terminus, GAP, GDP, GEF, Growth, GTP, GTPase, GTPase HRas, GTPase-activating, HRAS-GTP, KRAS, NRAS, Once, PI, Raf, Ras, RasGAP, SOS1, Subsequently, The
Bgee · 20
HRAS → amygdala, caudate nucleus, dentate gyrus of hippocampal formation granule cell, entorhinal cortex, esophagus, fetal liver hematopoietic progenitor cell, hypothalamus, lip, molar, muscle of thigh, nucleus accumbens, perirhinal cortex, putamen, right hemisphere of cerebellum, skin of abdomen, skin of leg, substantia nigra, superior frontal gyrus, temporal lobe, yolk sac
RNA expression pattern · 20
HRAS → amygdala, caudate nucleus, dentate gyrus of hippocampal formation granule cell, entorhinal cortex, esophagus, fetal liver hematopoietic progenitor cell, hypothalamus, lip, molar, muscle of thigh, nucleus accumbens, perirhinal cortex, putamen, right hemisphere of cerebellum, skin of abdomen, skin of leg, substantia nigra, superior frontal gyrus, temporal lobe, yolk sac
related to Bladder cancer · 12
HRAS → G12V, Gly12Val, H-RasV12, Mutations, One, Somatic, Some, Specifically, The, These, This, When
related to Costello syndrome · 9
HRAS → At, Costello, Each, G12S, Gly12Ser, Instead, Researchers, The, This
related to External links · 5
HRAS → Costello, GeneReviews/NCBI/NIH/UW, Medicine Medical Subject Headings, MeSH, National Library
related to Other cancers · 5
HRAS → DNA, Recent, Somatic, The HRAS, These
Band · 2
HRAS → 11p15.5, 7 F5|7 86.48 cM
Chr. · 2
HRAS → Chromosome 11 (human), Chromosome 7 (mouse)
Important terminology Word statistics
Frequent words and multi-word phrases across the lead, headings, infobox and body. Useful for terminology coverage.Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.
Important terminology
gene mutations protein cell cellular virus bp human chromosome 11 gtpase chr band oncogene cells growth costello syndrome cancer harvey
Entity relationships Subject–Predicate–Object triples
Extracted RDF-like relationships with confidence and source. The table includes structured facts and lower-confidence contextual relations.| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| HRAS | 3.6.5.2 | ↗ | 1.00 | infobox |
| HRAS | Aliases | HRAS, C-BAS/HAS, C-H-RAS, C-HA-RAS1, CTLO, H-RASIDX, HAMSV, HRAS1, RASH1, p21ras, Harvey rat sarcoma viral oncogene homolog, HRas proto-oncogene, GTPase, RASK2 | 1.00 | infobox |
| HRAS | Available structures | Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes121P, 1AA9, 1AGP, 1BKD, 1CLU, 1CRP, 1CRQ, 1CRR, 1CTQ, 1GNP, 1GNQ, 1GNR, 1HE8, 1IAQ, 1IOZ, 1JAH, 1JAI, 1K8R,… | 1.00 | infobox |
| HRAS | Band | 11p15.5 | 1.00 | infobox |
| HRAS | Band | 7 F5|7 86.48 cM | 1.00 | infobox |
| HRAS | Bgee | skin of abdomen | 1.00 | infobox |
| HRAS | Bgee | skin of leg | 1.00 | infobox |
| HRAS | Bgee | putamen | 1.00 | infobox |
| HRAS | Bgee | caudate nucleus | 1.00 | infobox |
| HRAS | Bgee | nucleus accumbens | 1.00 | infobox |
| HRAS | Bgee | hypothalamus | 1.00 | infobox |
| HRAS | Bgee | temporal lobe | 1.00 | infobox |
| HRAS | Bgee | amygdala | 1.00 | infobox |
| HRAS | Bgee | right hemisphere of cerebellum | 1.00 | infobox |
| HRAS | Bgee | substantia nigra | 1.00 | infobox |
| HRAS | Bgee | dentate gyrus of hippocampal formation granule cell | 1.00 | infobox |
| HRAS | Bgee | lip | 1.00 | infobox |
| HRAS | Bgee | molar | 1.00 | infobox |
| HRAS | Bgee | superior frontal gyrus | 1.00 | infobox |
| HRAS | Bgee | esophagus | 1.00 | infobox |
| HRAS | Bgee | fetal liver hematopoietic progenitor cell | 1.00 | infobox |
| HRAS | Bgee | yolk sac | 1.00 | infobox |
| HRAS | Bgee | entorhinal cortex | 1.00 | infobox |
| HRAS | Bgee | perirhinal cortex | 1.00 | infobox |
| HRAS | Bgee | muscle of thigh | 1.00 | infobox |
| HRAS | BioGPS | More reference expression data | 1.00 | infobox |
| HRAS | Chr. | Chromosome 11 (human) | 1.00 | infobox |
| HRAS | Chr. | Chromosome 7 (mouse) | 1.00 | infobox |
| HRAS | Databases | NCBI: entry; OMA: entry | 1.00 | infobox |
| HRAS | End | 537,321 bp | 1.00 | infobox |
No triples extracted yet.
Related concept clusters Concept neighborhoods
Clusters of nearby vocabulary surrounding the topic. Scan them for adjacent concepts and language you may have missed.These clusters group vocabulary that occurs around closely connected concepts in the source material.
Connections between topic areas Semantic bridges
Bridge nodes connect otherwise separate parts of the map. Expand a row to inspect the topic groups on each side.Bridges can reveal useful research angles that are easy to miss in a flat list of related terms.
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