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CBLB (gene)

CBL-B is an E3 ubiquitin-protein ligase that in humans is encoded by the CBLB gene. CBLB is a member of the CBL gene family.

Interactions, Clinical significance & Function

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Interactions

7 related topics

Clinical significance

2 related topics

Function

1 related topics

Overview

3 related topics

Key facts & relationships

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2.3.2.27
Aliases
CBLB, Cbl-b, RNF56, Nbla00127, Cbl proto-oncogene B
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2AK5, 2BZ8, 2DO6, 2J6F, 2JNH, 2LDR, 2OOA, 2OOB, 3PFV, 3VGO, 3ZNI
Band
3q13.11 · 16|16 B5
Bgee
pericardium · epithelium of colon · Achilles tendon · tail of epididymis · saphenous vein
BioGPS
More reference expression data

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Overview

Function

Clinical significance

Interactions

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Map overview Semantic statistics

CBLB (gene)

Nodes18
Edges17
Triples91
Avg. degree1.89
Density0.111111
Components1

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CBLB (gene)

Top relations

Gene ontology · 25
CBLB (gene) → calcium ion binding, cell surface receptor signaling pathway, cytoplasm, cytosol, epidermal growth factor receptor signaling pathway, membrane raft, metal ion binding, negative regulation of epidermal growth factor-activated receptor activity, NLS-bearing protein import into nucleus, nucleoplasm, nucleus, phosphotyrosine residue binding, plasma membrane, protein binding, protein ubiquitination, proteolysis, receptor tyrosine kinase binding, regulation of platelet-derived growth factor receptor-alpha signaling pathway, regulation of signaling, SH3 domain binding
Bgee · 20
CBLB (gene) → Achilles tendon, blood, cumulus cell, decidua, epithelium of colon, gastric mucosa, genital tubercle, hand, left lung lobe, lymph node, mesenteric lymph nodes, pericardium, renal corpuscle, saphenous vein, tail of embryo, tail of epididymis, tibia, tibial nerve, umbilical cord, visceral pleura
RNA expression pattern · 20
CBLB (gene) → Achilles tendon, blood, cumulus cell, decidua, epithelium of colon, gastric mucosa, genital tubercle, hand, left lung lobe, lymph node, mesenteric lymph nodes, pericardium, renal corpuscle, saphenous vein, tail of embryo, tail of epididymis, tibia, tibial nerve, umbilical cord, visceral pleura
Band · 2
CBLB (gene) → 16|16 B5, 3q13.11
Chr. · 2
CBLB (gene) → Chromosome 16 (mouse), Chromosome 3 (human)
End · 2
CBLB (gene) → 105,869,552 bp, 52,028,411 bp
2.3.2.27 · 1
CBLB (gene) → ↗
Aliases · 1
CBLB (gene) → CBLB, Cbl-b, RNF56, Nbla00127, Cbl proto-oncogene B
Available structures · 1
CBLB (gene) → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2AK5, 2BZ8, 2DO6, 2J6F, 2JNH, 2LDR, 2OOA, 2OOB, 3PFV, 3VGO, 3ZNI
BioGPS · 1
CBLB (gene) → More reference expression data

Important terminology Word statistics

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Important terminology

cblb gene bp human chr band chromosome cbl-b location cbl mouse receptor ubiquitin-protein ligase function external search activity 869 552

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
CBLB (gene)2.3.2.271.00infobox
CBLB (gene)AliasesCBLB, Cbl-b, RNF56, Nbla00127, Cbl proto-oncogene B1.00infobox
CBLB (gene)Available structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2AK5, 2BZ8, 2DO6, 2J6F, 2JNH, 2LDR, 2OOA, 2OOB, 3PFV, 3VGO, 3ZNI1.00infobox
CBLB (gene)Band3q13.111.00infobox
CBLB (gene)Band16|16 B51.00infobox
CBLB (gene)Bgeepericardium1.00infobox
CBLB (gene)Bgeeepithelium of colon1.00infobox
CBLB (gene)BgeeAchilles tendon1.00infobox
CBLB (gene)Bgeetail of epididymis1.00infobox
CBLB (gene)Bgeesaphenous vein1.00infobox
CBLB (gene)Bgeegastric mucosa1.00infobox
CBLB (gene)Bgeetibia1.00infobox
CBLB (gene)Bgeedecidua1.00infobox
CBLB (gene)Bgeetibial nerve1.00infobox
CBLB (gene)Bgeevisceral pleura1.00infobox
CBLB (gene)Bgeehand1.00infobox
CBLB (gene)Bgeegenital tubercle1.00infobox
CBLB (gene)Bgeetail of embryo1.00infobox
CBLB (gene)Bgeeumbilical cord1.00infobox
CBLB (gene)Bgeecumulus cell1.00infobox
CBLB (gene)Bgeerenal corpuscle1.00infobox
CBLB (gene)Bgeelymph node1.00infobox
CBLB (gene)Bgeeblood1.00infobox
CBLB (gene)Bgeeleft lung lobe1.00infobox
CBLB (gene)Bgeemesenteric lymph nodes1.00infobox
CBLB (gene)BioGPSMore reference expression data1.00infobox
CBLB (gene)Chr.Chromosome 3 (human)1.00infobox
CBLB (gene)Chr.Chromosome 16 (mouse)1.00infobox
CBLB (gene)DatabasesNCBI: entry; OMA: entry1.00infobox
CBLB (gene)End105,869,552 bp1.00infobox

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