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Small nuclear RNA

Small nuclear RNA (snRNA) is a class of small RNA molecules that are found within the splicing speckles and Cajal bodies of the cell nucleus in eukaryotic cells. The length of an average snRNA is approximately 150 nucleotides. They are transcribed by either RNA polymerase II or RNA polymerase III. Their primary function is in the processing of…

SnRNPs and human disease, Classes & Overview

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SnRNPs and human disease

Motor neurons SnoRNPs Neuromuscular Duchenne muscular dystrophy Dyskeratosis congenita

13 related topics

Classes

U4atac U7 U11 U12 Five-prime cap

11 related topics

Overview

Small RNA Cell nucleus Cajal bodies Eukaryotic RNA polymerase II

24 related topics

Post-transcriptional modification

Eukaryotes 2′-O-methylation Pseudouridylations SnoRNA Oligo-adenylation

6 related topics

Topics to explore

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Overview

Small RNA
Cell nucleus
Cajal bodies Cajal body
Eukaryotic
RNA polymerase II
RNA polymerase III
Messenger RNA
HnRNA
Transcription factors
7SK RNA
Telomeres Telomere
SnRNP
Sm proteins LSm
U1 spliceosomal RNA
U2 spliceosomal RNA
U4 spliceosomal RNA
U5 spliceosomal RNA
U6 spliceosomal RNA
Uridine
Gel electrophoresis
Small nucleolar RNAs Small nucleolar RNA
Biogenesis
Nucleolus
ScaRNAs Small Cajal body-specific RNA

Classes

U4atac U4atac minor spliceosomal RNA
U7 U7 small nuclear RNA
U11 U11 spliceosomal RNA
U12 U12 minor spliceosomal RNA
Five-prime cap
Nuclear pores
Survival of motor neuron
Spliceosome
Introns Intron
Histone
U6atac U6atac minor spliceosomal RNA

In the spliceosome

U1 snRNA

SnRNPs and human disease

Post-transcriptional modification

Eukaryotes
2′-O-methylation
Pseudouridylations Pseudouridylation
SnoRNA
Oligo-adenylation Oligo-adenylation?action=edit&redlink=1
RNA decay RNA decay?action=edit&redlink=1

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Small nuclear RNA

Nodes69

Edges68

Triples36

Avg. degree1.97

Density0.028986

Components1

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Small nuclear RNA

Top relations

related to In the spliceosome · 24

Small nuclear RNA → After, AT-AC, GT-AG, In, RNA, RNAs, Spliceosomes, The, Then, There, These, This, U1, U11, U12, U12-type, U2, U2-type, U4, U4/U6

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Important terminology

rna snrna small spliceosome snrnas u1 splicing nucleus nuclear snrnp shown proteins rnas snrnps form complex associated u2 u5 u6

Entity relationships Subject–Predicate–Object triples

Subject	Predicate	Object	Confidence	Src
the RNA-binding LSm proteins.The first class	instance of	ClassessnRNA are often divided into two classes based upon both common sequence features as well as associated protein factors	0.80	text
known as Sm-class snRNA	instance of	ClassessnRNA are often divided into two classes based upon both common sequence features as well as associated protein factors	0.80	text
is more widely studied	instance of	ClassessnRNA are often divided into two classes based upon both common sequence features as well as associated protein factors	0.80	text
consists of U1	instance of	ClassessnRNA are often divided into two classes based upon both common sequence features as well as associated protein factors	0.80	text
U2	instance of	ClassessnRNA are often divided into two classes based upon both common sequence features as well as associated protein factors	0.80	text
U4	instance of	ClassessnRNA are often divided into two classes based upon both common sequence features as well as associated protein factors	0.80	text
U4atac	instance of	ClassessnRNA are often divided into two classes based upon both common sequence features as well as associated protein factors	0.80	text
U5	instance of	ClassessnRNA are often divided into two classes based upon both common sequence features as well as associated protein factors	0.80	text
U7	instance of	ClassessnRNA are often divided into two classes based upon both common sequence features as well as associated protein factors	0.80	text
U11	instance of	ClassessnRNA are often divided into two classes based upon both common sequence features as well as associated protein factors	0.80	text
and U12	instance of	ClassessnRNA are often divided into two classes based upon both common sequence features as well as associated protein factors	0.80	text
snRNAs	instance of	These modifications are associated with snoRNA activity which canonically modify pre-mature rRNAs but have been observed in modifying other cellular RNA targets	0.80	text

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