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Modified-release dosage is a mechanism that (in contrast to immediate-release dosage) delivers a drug with a delay after its administration (delayed-release dosage) or for a prolonged period of time (extended-release dosage) or to a specific target in the body (targeted-release dosage).
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drug release used matrix sustained rate time controlled tablet drugs system sr delivery crs dosage released formulations period diffusion systems
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| Modified-release dosage | is a | mechanism that | 0.90 | text |
| sustained release where prolonged release is intended | instance of | Timed release has several distinct variants | 0.80 | text |
| pulse release | instance of | Timed release has several distinct variants | 0.80 | text |
| delayed release | instance of | Timed release has several distinct variants | 0.80 | text |
| food can affect the release rate.Dissolution systemsDissolution systems must have the system dissolved slowly in order for the drug to have sustained release properties which can be achieved by using appropriate salts and/or derivatives as well as coating the drug with a dissolving material | instance of | but factors | 0.80 | text |
| pH | instance of | They are significantly less affected by factors | 0.80 | text |
| food intake | instance of | They are significantly less affected by factors | 0.80 | text |
| GI motility | instance of | They are significantly less affected by factors | 0.80 | text |
| and differing intestinal environments | instance of | They are significantly less affected by factors | 0.80 | text |
| powders | instance of | Many types of forms of drugs use this method | 0.80 | text |
| capsules | instance of | Many types of forms of drugs use this method | 0.80 | text |
| and tablets.Bio-adhesive systemsBio-adhesive systems generally are meant to stick to mucus | instance of | Many types of forms of drugs use this method | 0.80 | text |
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