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MAPK8IP1: Interactions & Overview

C-jun-amino-terminal kinase-interacting protein 1 is an enzyme that in humans is encoded by the MAPK8IP1 gene.

Language: English [EN]
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MAPK8IP1 topic overview

The analysis highlights Interactions and Overview as prominent areas in the source structure around MAPK8IP1.

Related topics
14
Source areas
2
Connected nodes
16
Extracted relationships
111
Concept neighborhoods
7
Bridge connections
16

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Interactions · 11 topics
Overview · 3 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases
MAPK8IP1, IB1, JIP-1, JIP1, PRKM8IP, mitogen-activated protein kinase 8 interacting protein 1
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2G01, 2GMX, 2H96, 3OXI, 3PTG, 3VUD, 3VUG, 3VUH, 3VUI, 3VUK, 3VUL, 3VUM, 4E73, 4G1W, 4H39, 4HYS, 4HYU, 4IZY
Band
11p11.2 · 2|2 E1
Bgee
C1 segment · right frontal lobe · anterior pituitary · right hemisphere of cerebellum · tibial nerve
BioGPS
More reference expression data
Chr.
Chromosome 11 (human) · Chromosome 2 (mouse)

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Interactions

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How MAPK8IP1 connects Entity context

The extracted context around MAPK8IP1 shows recurring relationship patterns in the source. For example, MAPK8IP1 → axon, axonal growth cone, cell body, cytoplasm, cytosol, dendrite, dendritic growth cone, dentate gyrus mossy fiber, endoplasmic reticulum, endoplasmic reticulum membrane, JUN kinase binding, JUN phosphorylation, kinesin binding, MAP-kinase scaffold activity, membrane, mitochondrial membranes, mitochondrion, mitogen-activated protein kinase kinase binding, mitogen-activated protein kinase kinase kinase binding, negative regulation of apoptotic process Another extracted example is MAPK8IP1 → anterior cingulate cortex, anterior pituitary, Brodmann area 10, Brodmann area 9, C1 segment, central gray substance of midbrain, cerebellar cortex, dentate gyrus of hippocampal formation granule cell, dorsomedial hypothalamic nucleus, entorhinal cortex, gallbladder, perirhinal cortex, prefrontal cortex, primary visual cortex, right frontal lobe, right hemisphere of cerebellum, superior frontal gyrus, superior surface of tongue, tibial nerve, ventricular zone. Use these groups to spot repeated connection types before inspecting the individual relationships.

MAPK8IP1

Top relations

Gene ontology · 38
MAPK8IP1 → axon, axonal growth cone, cell body, cytoplasm, cytosol, dendrite, dendritic growth cone, dentate gyrus mossy fiber, endoplasmic reticulum, endoplasmic reticulum membrane, JUN kinase binding, JUN phosphorylation, kinesin binding, MAP-kinase scaffold activity, membrane, mitochondrial membranes, mitochondrion, mitogen-activated protein kinase kinase binding, mitogen-activated protein kinase kinase kinase binding, negative regulation of apoptotic process
Bgee · 20
MAPK8IP1 → anterior cingulate cortex, anterior pituitary, Brodmann area 10, Brodmann area 9, C1 segment, central gray substance of midbrain, cerebellar cortex, dentate gyrus of hippocampal formation granule cell, dorsomedial hypothalamic nucleus, entorhinal cortex, gallbladder, perirhinal cortex, prefrontal cortex, primary visual cortex, right frontal lobe, right hemisphere of cerebellum, superior frontal gyrus, superior surface of tongue, tibial nerve, ventricular zone
RNA expression pattern · 20
MAPK8IP1 → anterior cingulate cortex, anterior pituitary, Brodmann area 10, Brodmann area 9, C1 segment, central gray substance of midbrain, cerebellar cortex, dentate gyrus of hippocampal formation granule cell, dorsomedial hypothalamic nucleus, entorhinal cortex, gallbladder, perirhinal cortex, prefrontal cortex, primary visual cortex, right frontal lobe, right hemisphere of cerebellum, superior frontal gyrus, superior surface of tongue, tibial nerve, ventricular zone
related to Interactions · 10
MAPK8IP1 → DUSP16, LRP1, LRP2, MAP2K7, MAP3K10, MAP3K11, MAP3K12, MAPK8, MAPK8IP2, Mitogen-activated
Band · 2
MAPK8IP1 → 11p11.2, 2|2 E1
Chr. · 2
MAPK8IP1 → Chromosome 11 (human), Chromosome 2 (mouse)
End · 2
MAPK8IP1 → 45,906,465 bp, 92,231,608 bp
Aliases · 1
MAPK8IP1 → MAPK8IP1, IB1, JIP-1, JIP1, PRKM8IP, mitogen-activated protein kinase 8 interacting protein 1
Available structures · 1
MAPK8IP1 → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2G01, 2GMX, 2H96, 3OXI, 3PTG, 3VUD, 3VUG, 3VUH, 3VUI, 3VUK, 3VUL, 3VUM, 4E73, 4G1W, 4H39, 4HYS, 4HYU, 4IZY
BioGPS · 1
MAPK8IP1 → More reference expression data

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

protein gene bp kinase chr human band chromosome 11 mapk8 mouse transcription location mitogen-activated encoded regulator pancreatic beta cells function

MAPK8IP1 relationships Subject–Predicate–Object triples

TTTA extracted 111 structured relationships around MAPK8IP1. Examples in this analysis include MAPK8IP1 → Aliases → MAPK8IP1, IB1, JIP-1, JIP1, PRKM8IP, mitogen-activated protein kinase 8 interacting protein 1 and MAPK8IP1 → Available structures → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2G01, 2GMX, 2H96, 3OXI, 3PTG, 3VUD, 3VUG, 3VUH, 3VUI, 3VUK, 3VUL, 3VUM, 4E73, 4G1W, 4H39, 4HYS, 4HYU, 4IZY. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
MAPK8IP1AliasesMAPK8IP1, IB1, JIP-1, JIP1, PRKM8IP, mitogen-activated protein kinase 8 interacting protein 11.00infobox
MAPK8IP1Available structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2G01, 2GMX, 2H96, 3OXI, 3PTG, 3VUD, 3VUG, 3VUH, 3VUI, 3VUK, 3VUL, 3VUM, 4E73, 4G1W, 4H39, 4HYS, 4HYU, 4IZY1.00infobox
MAPK8IP1Band11p11.21.00infobox
MAPK8IP1Band2|2 E11.00infobox
MAPK8IP1BgeeC1 segment1.00infobox
MAPK8IP1Bgeeright frontal lobe1.00infobox
MAPK8IP1Bgeeanterior pituitary1.00infobox
MAPK8IP1Bgeeright hemisphere of cerebellum1.00infobox
MAPK8IP1Bgeetibial nerve1.00infobox
MAPK8IP1Bgeeanterior cingulate cortex1.00infobox
MAPK8IP1Bgeeprefrontal cortex1.00infobox
MAPK8IP1Bgeeventricular zone1.00infobox
MAPK8IP1BgeeBrodmann area 91.00infobox
MAPK8IP1BgeeBrodmann area 101.00infobox
MAPK8IP1Bgeesuperior frontal gyrus1.00infobox
MAPK8IP1Bgeeprimary visual cortex1.00infobox
MAPK8IP1Bgeeentorhinal cortex1.00infobox
MAPK8IP1Bgeeperirhinal cortex1.00infobox
MAPK8IP1Bgeecerebellar cortex1.00infobox
MAPK8IP1Bgeedentate gyrus of hippocampal formation granule cell1.00infobox
MAPK8IP1Bgeesuperior surface of tongue1.00infobox
MAPK8IP1Bgeegallbladder1.00infobox
MAPK8IP1Bgeedorsomedial hypothalamic nucleus1.00infobox
MAPK8IP1Bgeecentral gray substance of midbrain1.00infobox
MAPK8IP1BioGPSMore reference expression data1.00infobox
MAPK8IP1Chr.Chromosome 11 (human)1.00infobox
MAPK8IP1Chr.Chromosome 2 (mouse)1.00infobox
MAPK8IP1DatabasesNCBI: entry; OMA: entry1.00infobox
MAPK8IP1End45,906,465 bp1.00infobox
MAPK8IP1End92,231,608 bp1.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around MAPK8IP1 bring nearby vocabulary together. In this analysis, examples include Mitogen-activated, Search and Location. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • gene
    • Location
    • Mapk8ip1
    • Protein
    • Chromosome
    • Human
    • Bp
    • Chr
    • End
    • Expression
    • Function
    • Mitogen-activated
    • Search
  • mitogen-activated protein kinase 9
    • Search
    • Mapk8
    • Kinase
    • Protein
    • Mitogen-activated
    • Shown
    • Location
    • Mapk8ip1
    • Mouse
    • Transcription
    • Chromosome
    • End
  • re1-silencing transcription factor
    • Beta
    • Cells
    • Expression
    • Shown
    • Mapk8
    • Kinase
    • End
    • Function
    • Gene
    • Mitogen-activated
    • Pancreatic
    • Protein
  • mapk8
    • Shown
    • Mouse
    • Transcription
    • Protein
    • Similar
    • Beta
    • Cells
    • End
    • Expression
    • Mitogen-activated
    • Pancreatic
    • Regulator
  • MAPK8IP1
    • Mitogen-activated
    • Search
    • Location
    • Protein
    • Chromosome
    • Human
    • Kinase
    • Bp
    • Chr
    • End
    • Expression
    • Function
  • mapk8ip1
    • Mitogen-activated
    • Search
    • Location
    • Protein
    • Chromosome
    • Human
    • Kinase
    • Bp
    • Chr
    • End
    • Expression
    • Function
  • enzyme
    • Humans
    • Kinase-interacting
    • Encoded
    • Mapk8ip1
    • Gene
    • Protein

Connections between topic areas Semantic bridges

For MAPK8IP1, one of the stronger structural bridges in this analysis connects MAPK8IP1 with Interactions. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
MAPK8IP1Interactions · splits 5 ⟂ 12
MAPK8IP1Overview · splits 13 ⟂ 4

Map overview Semantic statistics

MAPK8IP1

Nodes17
Edges16
Triples111
Avg. degree1.88
Density0.117647
Components1

Source & methodology

TTTA analyzes the structure around MAPK8IP1 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Interactions & Overview, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — MAPK8IP1 · EN edition · Analysis: TopicsToTalkAbout

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