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Monoamine oxidase inhibitor

Monoamine oxidase inhibitors (MAOIs) are a class of drugs that inhibit one or both monoamine oxidase enzymes: monoamine oxidase A (MAO-A) and monoamine oxidase B (MAO-B). These enzymes metabolize monoamine neurotransmitters and related amines, including serotonin, norepinephrine, dopamine, epinephrine, tyramine, and several trace amines.

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ATC code
N06AF
Biological target
Monoamine oxidase enzymes: MAO-A and/or MAO-B
Mechanism of action
Enzyme inhibitor
MeSH
D008996
Synonyms
MAOI, RIMA
Use
Treatment of major depressive disorder, treatment-resistant depression, atypical depression, Parkinson's disease, and several other disorders

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Overview

Medical uses

Adverse effects

Drug interactions

Pharmacology

History

Classic irreversible antidepressant MAOIs

Reversible MAO-A inhibitors

Other drugs with MAOI activity

Naturally occurring reversible MAOIs

Withdrawn or discontinued MAOIs

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Map overview Semantic statistics

Monoamine oxidase inhibitor

Nodes120
Edges119
Triples38
Avg. degree1.98
Density0.016667
Components1

How this topic connects Entity context

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Monoamine oxidase inhibitor

Top relations

ATC code · 1
Monoamine oxidase inhibitor → N06AF
Biological target · 1
Monoamine oxidase inhibitor → Monoamine oxidase enzymes: MAO-A and/or MAO-B
Mechanism of action · 1
Monoamine oxidase inhibitor → Enzyme inhibitor
MeSH · 1
Monoamine oxidase inhibitor → D008996
Synonyms · 1
Monoamine oxidase inhibitor → MAOI, RIMA
Use · 1
Monoamine oxidase inhibitor → Treatment of major depressive disorder, treatment-resistant depression, atypical depression, Parkinson's disease, and several other disorders

Important terminology Word statistics

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Important terminology

maois maoi tyramine mao-a mao-b serotonin classic inhibitors dietary used risk also drugs guidance activity antidepressant may modern reuptake inhibition

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Monoamine oxidase inhibitorATC codeN06AF1.00infobox
Monoamine oxidase inhibitorBiological targetMonoamine oxidase enzymes: MAO-A and/or MAO-B1.00infobox
Monoamine oxidase inhibitorMechanism of actionEnzyme inhibitor1.00infobox
Monoamine oxidase inhibitorMeSHD0089961.00infobox
Monoamine oxidase inhibitorSynonymsMAOI, RIMA1.00infobox
Monoamine oxidase inhibitorUseTreatment of major depressive disorder, treatment-resistant depression, atypical depression, Parkinson's disease, and several other disorders1.00infobox
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sauerkrautinstance ofand fermented products0.80text
Marmiteinstance ofand fermented products0.80text
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