KLF15

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Gene regulation

HSD17B5 Testosterone BMPER Sp1 Endothelin-1

25 related topics

Clinical significance

Gluconeogenic Metformin Aortic aneurysm P53 P300

15 related topics

Expression

Glucocorticoid receptor PI3K Phosphoenolpyruvate carboxykinase Stearoyl-CoA desaturase-1 Oxidative stress

6 related topics

Overview

Protein Gene Krüppel-like factor

3 related topics

Key facts & relationships

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Aliases: KLF15, KKLF, Kruppel-like factor 15, Kruppel like factor 15
Available structures: Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2ENT
Band: 3q21.3 · 6|6 D1
Bgee: parotid gland · cardia · lower lobe of lung · sural nerve · renal medulla
BioGPS: n/a
Chr.: Chromosome 3 (human) · Chromosome 6 (mouse)

Topics to explore

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Overview

Protein
Gene
Krüppel-like factor Kruppel-like factors

Expression

Gene regulation

HSD17B5 AKR1C3
Testosterone
BMPER
Sp1 Sp1 transcription factor
Endothelin-1
LRP5
MEF2A
GLUT4
MiR-133 Mir-133 microRNA precursor family
TGFbeta1 TGF beta 1
Adenoviral Adenoviridae
CTGF
TGFbeta
P38 MAPK P38 mitogen-activated protein kinases
Acetyl-CoA synthetase 2 ACSS1?action=edit&redlink=1
Citric acid cycle
Mitochondrial
Progesterone receptor
E2F1
Progestins Progestin
GATA4
MEF2
BCAT2 BCAT2?action=edit&redlink=1
Atrogin-1 FBXO32
SMuRF1

Clinical significance

Gluconeogenic Gluconeogenesis
Metformin
Aortic aneurysm
P53
P300 EP300
Acetyltransferase
Acetylation
3T3-L1
Adipocytes Adipocyte
PPAR-γ Peroxisome proliferator-activated receptor gamma
3T3 cells
TFIIH Transcription factor II H
CREB-binding protein
Hepatitis B virus
KChIP2 KCNIP2

Advanced semantic analysis

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Map overview Semantic statistics

Nodes54

Edges53

Triples104

Avg. degree1.96

Density0.037037

Components1

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KLF15

Top relations

Gene ontology · 25

KLF15 → cardiac muscle hypertrophy in response to stress, cellular glucose homeostasis, cellular response to peptide, DNA binding, DNA-binding transcription activator activity, RNA polymerase II-specific, DNA-binding transcription factor activity, DNA-binding transcription factor activity, RNA polymerase II-specific, glial cell differentiation, glomerular visceral epithelial cell differentiation, metal ion binding, negative regulation of peptidyl-lysine acetylation, nucleic acid binding, nucleus, positive regulation of glucose import, positive regulation of transcription by RNA polymerase II, positive regulation of transcription, DNA-templated, protein binding, regulation of gene expression, regulation of transcription by RNA polymerase II, regulation of transcription, DNA-templated

Bgee · 19

KLF15 → cardia, external globus pallidus, gastric mucosa, inferior ganglion of vagus nerve, interventricular septum, lacrimal gland, left lobe of liver, lower lobe of lung, masseter muscle, muscle of thigh, parotid gland, proximal tubule, renal medulla, retinal pigment epithelium, right kidney, right lobe of liver, sural nerve, ventral tegmental area, vestibular membrane of cochlear duct

RNA expression pattern · 19

related to Gene regulation · 6

KLF15 → BMPER, H295R, HSD17B5, In, RT-PCR, SP1

related to Clinical significance · 5

KLF15 → Conversely, Finally, Klf15-deficient, Mice, These

related to Expression · 5

KLF15 → Activated, Forced, Insulin, PEPCK, PI3K

Band · 2

KLF15 → 3q21.3, 6|6 D1

Chr. · 2

KLF15 → Chromosome 3 (human), Chromosome 6 (mouse)

End · 2

KLF15 → 126,357,408 bp, 90,452,220 bp

is a · 2

KLF15 → novel transcriptional activator for hepatitis B virus core and surface promoters, strong and direct activator of BMPER expression which is inhibited by SP1

Important terminology Word statistics

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Important terminology

expression gene promoter factor human bp insulin mice kklf chr band cells protein ctgf inhibits heart krüppel-like chromosome muscle binding

Entity relationships Subject–Predicate–Object triples

Subject	Predicate	Object	Confidence	Src
KLF15	Aliases	KLF15, KKLF, Kruppel-like factor 15, Kruppel like factor 15	1.00	infobox
KLF15	Available structures	Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2ENT	1.00	infobox
KLF15	Band	3q21.3	1.00	infobox
KLF15	Band	6\|6 D1	1.00	infobox
KLF15	Bgee	parotid gland	1.00	infobox
KLF15	Bgee	cardia	1.00	infobox
KLF15	Bgee	lower lobe of lung	1.00	infobox
KLF15	Bgee	sural nerve	1.00	infobox
KLF15	Bgee	renal medulla	1.00	infobox
KLF15	Bgee	gastric mucosa	1.00	infobox
KLF15	Bgee	right lobe of liver	1.00	infobox
KLF15	Bgee	inferior ganglion of vagus nerve	1.00	infobox
KLF15	Bgee	ventral tegmental area	1.00	infobox
KLF15	Bgee	external globus pallidus	1.00	infobox
KLF15	Bgee	left lobe of liver	1.00	infobox
KLF15	Bgee	lacrimal gland	1.00	infobox
KLF15	Bgee	interventricular septum	1.00	infobox
KLF15	Bgee	vestibular membrane of cochlear duct	1.00	infobox
KLF15	Bgee	right kidney	1.00	infobox
KLF15	Bgee	proximal tubule	1.00	infobox
KLF15	Bgee	muscle of thigh	1.00	infobox
KLF15	Bgee	masseter muscle	1.00	infobox
KLF15	Bgee	retinal pigment epithelium	1.00	infobox
KLF15	BioGPS	n/a	1.00	infobox
KLF15	Chr.	Chromosome 3 (human)	1.00	infobox
KLF15	Chr.	Chromosome 6 (mouse)	1.00	infobox
KLF15	Databases	NCBI: entry; OMA: entry	1.00	infobox
KLF15	End	126,357,408 bp	1.00	infobox
KLF15	End	90,452,220 bp	1.00	infobox
KLF15	Ensembl	ENSG00000163884	1.00	infobox

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