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Myocyte-specific enhancer factor 2A

Myocyte-specific enhancer factor 2A is a protein that in humans is encoded by the MEF2A gene. MEF2A is a transcription factor in the Mef2 family. In humans it is located on chromosome 15q26. Certain mutations in MEF2A cause an autosomal dominant form of coronary artery disease and myocardial infarction.

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Interactions

InteractASCL1EP300HDAC4HDAC9
10 related topics

Overview

ProteinGeneTranscription factorMef2Chromosome 15q26
9 related topics

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Aliases
MEF2A, ADCAD1, RSRFC4, RSRFC9, mef2, myocyte enhancer factor 2A
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1C7U, 1EGW, 1LEW, 3KOV, 3MU6, 3P57
Band
15q26.3 · 7 C|7 36.72 cM
Bgee
Achilles tendon · myocardium · cardiac muscle tissue of right atrium · right ventricle · myocardium of left ventricle
BioGPS
More reference expression data
Chr.
Chromosome 15 (human) · Chromosome 7 (mouse)

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Myocyte-specific enhancer factor 2A

Nodes22
Edges21
Triples115
Avg. degree1.91
Density0.090909
Components1

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Myocyte-specific enhancer factor 2A

Top relations

Gene ontology · 44
Myocyte-specific enhancer factor 2A → apoptotic process, cardiac conduction, cell differentiation, cellular response to calcium ion, chromatin binding, cytosol, dendrite morphogenesis, development of the heart, DNA binding, DNA-binding transcription activator activity, RNA polymerase II-specific, DNA-binding transcription factor activity, DNA-binding transcription factor activity, RNA polymerase II-specific, ERK5 cascade, histone acetyltransferase binding, histone deacetylase binding, MAPK cascade, mitochondrial genome maintenance, mitochondrion distribution, multicellular organism development, muscle organ development
Bgee · 19
Myocyte-specific enhancer factor 2A → Achilles tendon, ankle, atrioventricular valve, atrium, biceps brachii, cardiac muscle tissue of right atrium, cerebellar vermis, lateral geniculate nucleus, lateral septal nucleus, medial dorsal nucleus, medial geniculate nucleus, middle temporal gyrus, myocardium, myocardium of left ventricle, right ventricle, Skeletal muscle tissue of biceps brachii, skin of thigh, stroma of bone marrow, tibia
RNA expression pattern · 19
Myocyte-specific enhancer factor 2A → Achilles tendon, ankle, atrioventricular valve, atrium, biceps brachii, cardiac muscle tissue of right atrium, cerebellar vermis, lateral geniculate nucleus, lateral septal nucleus, medial dorsal nucleus, medial geniculate nucleus, middle temporal gyrus, myocardium, myocardium of left ventricle, right ventricle, Skeletal muscle tissue of biceps brachii, skin of thigh, stroma of bone marrow, tibia
related to Interactions · 9
Myocyte-specific enhancer factor 2A → ASCL1, EP300, HDAC4, HDAC9, Histone, MAPK14, MEF2D, Mothers, Myocyte-specific
Band · 2
Myocyte-specific enhancer factor 2A → 15q26.3, 7 C|7 36.72 cM
Chr. · 2
Myocyte-specific enhancer factor 2A → Chromosome 15 (human), Chromosome 7 (mouse)
End · 2
Myocyte-specific enhancer factor 2A → 67,372,858 bp, 99,716,488 bp
Aliases · 1
Myocyte-specific enhancer factor 2A → MEF2A, ADCAD1, RSRFC4, RSRFC9, mef2, myocyte enhancer factor 2A
Available structures · 1
Myocyte-specific enhancer factor 2A → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1C7U, 1EGW, 1LEW, 3KOV, 3MU6, 3P57
BioGPS · 1
Myocyte-specific enhancer factor 2A → More reference expression data

Important terminology Word statistics

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Important terminology

mef2a bp gene human factor chromosome chr band enhancer mef2 15 2a transcription location myocyte-specific family humans protein mouse dna

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Myocyte-specific enhancer factor 2AAliasesMEF2A, ADCAD1, RSRFC4, RSRFC9, mef2, myocyte enhancer factor 2A1.00infobox
Myocyte-specific enhancer factor 2AAvailable structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1C7U, 1EGW, 1LEW, 3KOV, 3MU6, 3P571.00infobox
Myocyte-specific enhancer factor 2ABand15q26.31.00infobox
Myocyte-specific enhancer factor 2ABand7 C|7 36.72 cM1.00infobox
Myocyte-specific enhancer factor 2ABgeeAchilles tendon1.00infobox
Myocyte-specific enhancer factor 2ABgeemyocardium1.00infobox
Myocyte-specific enhancer factor 2ABgeecardiac muscle tissue of right atrium1.00infobox
Myocyte-specific enhancer factor 2ABgeeright ventricle1.00infobox
Myocyte-specific enhancer factor 2ABgeemyocardium of left ventricle1.00infobox
Myocyte-specific enhancer factor 2ABgeebiceps brachii1.00infobox
Myocyte-specific enhancer factor 2ABgeeSkeletal muscle tissue of biceps brachii1.00infobox
Myocyte-specific enhancer factor 2ABgeeskin of thigh1.00infobox
Myocyte-specific enhancer factor 2ABgeemiddle temporal gyrus1.00infobox
Myocyte-specific enhancer factor 2ABgeetibia1.00infobox
Myocyte-specific enhancer factor 2ABgeemedial dorsal nucleus1.00infobox
Myocyte-specific enhancer factor 2ABgeelateral geniculate nucleus1.00infobox
Myocyte-specific enhancer factor 2ABgeelateral septal nucleus1.00infobox
Myocyte-specific enhancer factor 2ABgeemedial geniculate nucleus1.00infobox
Myocyte-specific enhancer factor 2ABgeeatrioventricular valve1.00infobox
Myocyte-specific enhancer factor 2ABgeestroma of bone marrow1.00infobox
Myocyte-specific enhancer factor 2ABgeeatrium1.00infobox
Myocyte-specific enhancer factor 2ABgeecerebellar vermis1.00infobox
Myocyte-specific enhancer factor 2ABgeeankle1.00infobox
Myocyte-specific enhancer factor 2ABioGPSMore reference expression data1.00infobox
Myocyte-specific enhancer factor 2AChr.Chromosome 15 (human)1.00infobox
Myocyte-specific enhancer factor 2AChr.Chromosome 7 (mouse)1.00infobox
Myocyte-specific enhancer factor 2ADatabasesNCBI: entry; OMA: entry1.00infobox
Myocyte-specific enhancer factor 2AEnd99,716,488 bp1.00infobox
Myocyte-specific enhancer factor 2AEnd67,372,858 bp1.00infobox
Myocyte-specific enhancer factor 2AEnsemblENSG000000683051.00infobox

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