E2F1

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Interactions

Interact ARID3A CUL1 Cyclin A1 Cyclin A2

23 related topics

Function

Transcription factors Cell cycle Tumor suppressor DNA binding domain Retinoblastoma protein

7 related topics

Overview

Protein Gene

2 related topics

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases: E2F1, E2F-1, RBAP1, RBBP3, RBP3, E2F transcription factor 1
Available structures: Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1H24, 1O9K, 2AZE
Band: 20q11.22 · 2 H1|2 76.79 cM
Bgee: ganglionic eminence · secondary oocyte · ventricular zone · gonad · mucosa of transverse colon
BioGPS: More reference expression data
Chr.: Chromosome 20 (human) · Chromosome 2 (mouse)

Topics to explore

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Overview

Function

Transcription factors Transcription factor
Cell cycle
Tumor suppressor
DNA binding domain
Retinoblastoma protein
P53
Apoptosis

Interactions

Interact Protein-protein interaction
ARID3A
CUL1
Cyclin A1
Cyclin A2
GTF2H1
MDM4
NCOA6
NDN NDN (gene)
NPDC1
PURA
PHB Prohibitin
UDG Cyclin-like uracil DNA glycosylase?action=edit&redlink=1
RBL1 Retinoblastoma-like protein 1
SKP2
SP1 Sp1 transcription factor
SP2 Sp2 transcription factor
SP3 Sp3 transcription factor
SP4 Sp4 transcription factor
TFDP1
TOPBP1
TP53BP1
UBC Ubiquitin C

Advanced semantic analysis

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Map overview Semantic statistics

Nodes36

Edges35

Triples142

Avg. degree1.94

Density0.055556

Components1

How this topic connects Entity context

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E2F1

Top relations

Gene ontology · 54

E2F1 → anoikis, apoptotic process, cell cycle, cellular response to fatty acid, cellular response to hypoxia, cellular response to nerve growth factor stimulus, cellular response to xenobiotic stimulus, centrosome, cis-regulatory region sequence-specific DNA binding, cytoplasm, DNA binding, DNA damage checkpoint signaling, DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest, DNA-binding transcription activator activity, RNA polymerase II-specific, DNA-binding transcription factor activity, DNA-binding transcription factor activity, RNA polymerase II-specific, DNA-binding transcription repressor activity, RNA polymerase II-specific, forebrain development, intrinsic apoptotic signaling pathway by p53 class mediator, intrinsic apoptotic signaling pathway in response to DNA damage

related to Interactions · 21

E2F1 → ARID3A, CUL1, Cyclin A1, Cyclin A2, GTF2H1, MDM4, NCOA6, NDN, NPDC1, PHB, PURA, RB1, RBL1, SKP2, SP1, SP2, SP3, SP4, TFDP1TOPBP1, TP53BP1

Bgee · 18

E2F1 → bone marrow, ectoderm, fetal liver hematopoietic progenitor cell, ganglionic eminence, gastrula, gonad, mucosa of transverse colon, otic placode, otic vesicle, prefrontal cortex, primary oocyte, putamen, saccule, secondary oocyte, stromal cell of endometrium, testicle, ventricular zone, zygote

RNA expression pattern · 18

related to External links · 6

E2F1 → FactorBookE2F1 This, Medicine, Medicine Medical Subject Headings, MeSH, National Library, United States National Library

Band · 2

E2F1 → 2 H1|2 76.79 cM, 20q11.22

Chr. · 2

E2F1 → Chromosome 2 (mouse), Chromosome 20 (human)

End · 2

E2F1 → 154,411,812 bp, 33,686,385 bp

Aliases · 1

E2F1 → E2F1, E2F-1, RBAP1, RBBP3, RBP3, E2F transcription factor 1

Available structures · 1

E2F1 → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1H24, 1O9K, 2AZE

Important terminology Word statistics

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Important terminology

bp protein transcription human gene chr band e2f factor chromosome 20 location mouse cell dna binding function external family proteins

Entity relationships Subject–Predicate–Object triples

Subject	Predicate	Object	Confidence	Src
E2F1	Aliases	E2F1, E2F-1, RBAP1, RBBP3, RBP3, E2F transcription factor 1	1.00	infobox
E2F1	Available structures	Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1H24, 1O9K, 2AZE	1.00	infobox
E2F1	Band	20q11.22	1.00	infobox
E2F1	Band	2 H1\|2 76.79 cM	1.00	infobox
E2F1	Bgee	ganglionic eminence	1.00	infobox
E2F1	Bgee	secondary oocyte	1.00	infobox
E2F1	Bgee	ventricular zone	1.00	infobox
E2F1	Bgee	gonad	1.00	infobox
E2F1	Bgee	mucosa of transverse colon	1.00	infobox
E2F1	Bgee	stromal cell of endometrium	1.00	infobox
E2F1	Bgee	prefrontal cortex	1.00	infobox
E2F1	Bgee	testicle	1.00	infobox
E2F1	Bgee	bone marrow	1.00	infobox
E2F1	Bgee	putamen	1.00	infobox
E2F1	Bgee	zygote	1.00	infobox
E2F1	Bgee	ectoderm	1.00	infobox
E2F1	Bgee	otic vesicle	1.00	infobox
E2F1	Bgee	otic placode	1.00	infobox
E2F1	Bgee	primary oocyte	1.00	infobox
E2F1	Bgee	fetal liver hematopoietic progenitor cell	1.00	infobox
E2F1	Bgee	saccule	1.00	infobox
E2F1	Bgee	gastrula	1.00	infobox
E2F1	BioGPS	More reference expression data	1.00	infobox
E2F1	Chr.	Chromosome 20 (human)	1.00	infobox
E2F1	Chr.	Chromosome 2 (mouse)	1.00	infobox
E2F1	Databases	NCBI: entry; OMA: entry	1.00	infobox
E2F1	End	33,686,385 bp	1.00	infobox
E2F1	End	154,411,812 bp	1.00	infobox
E2F1	Ensembl	ENSG00000101412	1.00	infobox
E2F1	Entrez	1869	1.00	infobox

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