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Low-density lipoprotein receptor-related protein 5 is a protein that in humans is encoded by the LRP5 gene. LRP5 is a key component of the LRP5/LRP6/Frizzled co-receptor group that is involved in canonical Wnt pathway. Mutations in LRP5 can lead to considerable changes in bone mass. A loss-of-function mutation causes osteoporosis pseudoglioma syndrome…
Clinical significance, Transcription & Interactions
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bone protein wnt gene mass bp lrp6 human expression pathway chr band mutations receptor canonical chromosome 11 mrna mice also
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| LRP5 | Aliases | LRP5, BMND1, EVR1, EVR4, HBM, LR3, LRP-5, LRP7, OPPG, OPS, OPTA1, VBCH2, LDL receptor related protein 5, PCLD4, LRP-7 | 1.00 | infobox |
| LRP5 | Band | 11q13.2 | 1.00 | infobox |
| LRP5 | Band | 19|19 A | 1.00 | infobox |
| LRP5 | Bgee | right lobe of liver | 1.00 | infobox |
| LRP5 | Bgee | mucosa of transverse colon | 1.00 | infobox |
| LRP5 | Bgee | ascending aorta | 1.00 | infobox |
| LRP5 | Bgee | apex of heart | 1.00 | infobox |
| LRP5 | Bgee | minor salivary glands | 1.00 | infobox |
| LRP5 | Bgee | Descending thoracic aorta | 1.00 | infobox |
| LRP5 | Bgee | popliteal artery | 1.00 | infobox |
| LRP5 | Bgee | tibial arteries | 1.00 | infobox |
| LRP5 | Bgee | olfactory zone of nasal mucosa | 1.00 | infobox |
| LRP5 | Bgee | right coronary artery | 1.00 | infobox |
| LRP5 | Bgee | epithelium of urethra | 1.00 | infobox |
| LRP5 | Bgee | male urethra | 1.00 | infobox |
| LRP5 | Bgee | yolk sac | 1.00 | infobox |
| LRP5 | Bgee | epithelium of male urethra | 1.00 | infobox |
| LRP5 | Bgee | female urethra | 1.00 | infobox |
| LRP5 | Bgee | epithelium of female urethra | 1.00 | infobox |
| LRP5 | Bgee | muscle layer of urethra | 1.00 | infobox |
| LRP5 | Bgee | lip | 1.00 | infobox |
| LRP5 | Bgee | spermatid | 1.00 | infobox |
| LRP5 | Bgee | genital tubercle | 1.00 | infobox |
| LRP5 | BioGPS | More reference expression data | 1.00 | infobox |
| LRP5 | Chr. | Chromosome 11 (human) | 1.00 | infobox |
| LRP5 | Chr. | Chromosome 19 (mouse) | 1.00 | infobox |
| LRP5 | Databases | NCBI: entry; OMA: entry | 1.00 | infobox |
| LRP5 | End | 68,449,275 bp | 1.00 | infobox |
| LRP5 | End | 3,736,564 bp | 1.00 | infobox |
| LRP5 | Ensembl | ENSG00000162337 | 1.00 | infobox |
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