CCN family member 2

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Explore the main themes, entities and connections around CCN family member 2. Start with the topic map, then use the sections below for research and deeper semantic analysis.

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Structure and binding partners

Cysteine IGFBP VWC Cysteine knot Integrin receptors

14 related topics

Clinical significance

Wound healing Fibrotic TGF-β Fibrosis Bleomycin

8 related topics

Role in development

Chondrodysplasia Pancreatic beta cell Ovarian follicle Ovulation

4 related topics

Overview

Gene Matricellular protein Extracellular matrix Heparin CCN intercellular signaling protein

10 related topics

Key facts & relationships

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Aliases: CCN2, HCS24, IGFBP8, NOV2, connective tissue growth factor, cellular communication network factor 2, CTGF
Band: 6q23.2 · 10 A4|10 11.84 cM
Bgee: tibia · thoracic aorta · ascending aorta · smooth muscle tissue · gastric mucosa
BioGPS: More reference expression data
Chr.: Chromosome 6 (human) · Chromosome 10 (mouse)
Databases: NCBI: entry; OMA: entry

Topics to explore

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Overview

Role in development

Clinical significance

Advanced semantic analysis

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Map overview Semantic statistics

Nodes41

Edges40

Triples122

Avg. degree1.95

Density0.04878

Components1

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CCN family member 2

Top relations

Gene ontology · 64

CCN family member 2 → ageing, angiogenesis, cartilage condensation, cell adhesion, cell cortex, cell differentiation, cell migration, cell-cell signaling, cell-matrix adhesion, chondrocyte proliferation, cis-Golgi network, collagen-containing extracellular matrix, connective tissue development, cytosol, DNA biosynthetic process, epidermis development, extracellular matrix, extracellular matrix constituent secretion, extracellular region, extracellular space

Bgee · 19

CCN family member 2 → ankle, ankle joint, aortic valve, ascending aorta, ciliary body, Descending thoracic aorta, epithelium of lens, gallbladder, gastric mucosa, left coronary artery, right coronary artery, semi-lunar valve, skin of external ear, smooth muscle tissue, stroma of bone marrow, tendon of biceps brachii, thoracic aorta, tibia, tunica media of zone of aorta

RNA expression pattern · 19

Band · 2

CCN family member 2 → 10 A4|10 11.84 cM, 6q23.2

Chr. · 2

CCN family member 2 → Chromosome 10 (mouse), Chromosome 6 (human)

End · 2

CCN family member 2 → 131,951,372 bp, 24,474,581 bp

Aliases · 1

CCN family member 2 → CCN2, HCS24, IGFBP8, NOV2, connective tissue growth factor, cellular communication network factor 2, CTGF

BioGPS · 1

CCN family member 2 → More reference expression data

Databases · 1

CCN family member 2 → NCBI: entry; OMA: entry

Ensembl · 1

CCN family member 2 → ENSG00000118523

Important terminology Word statistics

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Important terminology

ctgf also bp gene human protein chr band growth tissue ccn2 development ccn family factor chromosome extracellular cell location fibrosis

Entity relationships Subject–Predicate–Object triples

Subject	Predicate	Object	Confidence	Src
CCN family member 2	Aliases	CCN2, HCS24, IGFBP8, NOV2, connective tissue growth factor, cellular communication network factor 2, CTGF	1.00	infobox
CCN family member 2	Band	6q23.2	1.00	infobox
CCN family member 2	Band	10 A4\|10 11.84 cM	1.00	infobox
CCN family member 2	Bgee	tibia	1.00	infobox
CCN family member 2	Bgee	thoracic aorta	1.00	infobox
CCN family member 2	Bgee	ascending aorta	1.00	infobox
CCN family member 2	Bgee	smooth muscle tissue	1.00	infobox
CCN family member 2	Bgee	gastric mucosa	1.00	infobox
CCN family member 2	Bgee	right coronary artery	1.00	infobox
CCN family member 2	Bgee	gallbladder	1.00	infobox
CCN family member 2	Bgee	Descending thoracic aorta	1.00	infobox
CCN family member 2	Bgee	left coronary artery	1.00	infobox
CCN family member 2	Bgee	tendon of biceps brachii	1.00	infobox
CCN family member 2	Bgee	tunica media of zone of aorta	1.00	infobox
CCN family member 2	Bgee	stroma of bone marrow	1.00	infobox
CCN family member 2	Bgee	semi-lunar valve	1.00	infobox
CCN family member 2	Bgee	ankle joint	1.00	infobox
CCN family member 2	Bgee	aortic valve	1.00	infobox
CCN family member 2	Bgee	skin of external ear	1.00	infobox
CCN family member 2	Bgee	ankle	1.00	infobox
CCN family member 2	Bgee	ciliary body	1.00	infobox
CCN family member 2	Bgee	epithelium of lens	1.00	infobox
CCN family member 2	BioGPS	More reference expression data	1.00	infobox
CCN family member 2	Chr.	Chromosome 6 (human)	1.00	infobox
CCN family member 2	Chr.	Chromosome 10 (mouse)	1.00	infobox
CCN family member 2	Databases	NCBI: entry; OMA: entry	1.00	infobox
CCN family member 2	End	131,951,372 bp	1.00	infobox
CCN family member 2	End	24,474,581 bp	1.00	infobox
CCN family member 2	Ensembl	ENSG00000118523	1.00	infobox
CCN family member 2	Entrez	1490	1.00	infobox

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