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Mef2

In the field of molecular biology, myocyte enhancer factor-2 (Mef2) proteins are a family of transcription factors which through control of gene expression are important regulators of cellular differentiation and consequently play a critical role in embryonic development. In adult organisms, Mef2 proteins mediate the stress response in some tissues. Mef2…

Species distribution, Function & Discovery

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Species distribution

EukaryotesYeastVertebratesMEF2AMEF2B
7 related topics

Function

BHLHNeural crestCraniofacialHomeodomainDLX5
7 related topics

Discovery

PromoterCreatine kinaseGeneEnhancerCoding sequences
6 related topics

Sequence and structure

N-terminalC-terminalNLS
3 related topics

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Discovery

Species distribution

Sequence and structure

Function

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Map overview Semantic statistics

Mef2

Nodes38
Edges37
Triples91
Avg. degree1.95
Density0.052632
Components1

How this topic connects Entity context

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Mef2

Top relations

related to Additional Information · 17
Mef2 → Another, Black, Both, Ca, Chen, Each MEF2, If MEF2C, II, Karamboulas, MEF2A, MEF2C, MicroRNA's, Myocyte Enhancer Factor, RNAs, Tdgf1, The, The Type-I
related to References · 14
Mef2 → Black, Brian, Chen, Cripps, Disease, Heart Development, Human Diseases, MEF2 Signaling, Myocyte Enhancer Factor, Oncotarget, Regeneration, Richard, Transcription Factors, Xiao
related to Sequence and structure · 12
Mef2 → All, C-terminal, C-terminus, D-Mef2, DNA-binding, MADS-box, Mef2A, MEF2B, N-terminal MADS-box, NLS, The MADS-box, Through
related to Discovery · 9
Mef2 → MCK, Mef2A, Mef2B, Mef2D, Related, RSRF, RSRFs, Serum Response Factor, Three
related to External links · 8
Mef2 → Arabidopsis, Drosophila, EukaryotesMEF2, Medicine Medical Subject Headings, MeSH, National Library, OrthoDB Orthology, SMP1
related to Cardiovascular system · 7
Mef2 → AHF, Each, In, Mef2a, Mef2b, Mef2c, Mef2d
related to Knockout studies · 7
Mef2 → AHF, In, Mef2c, Mice, This, Thus, When Mef2c
related to Development · 6
Mef2 → DLX5, DLX6, In Drosophila, Loss, Mammalian Mef2, Mef2c
related to Species distribution · 6
Mef2 → MEF2A, MEF2B, MEF2C, MEF2D, The Mef2, While Drosophila
related to Stress response · 1
Mef2 → In

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Important terminology

mef2c development gene heart transcription factors proteins enhancer protein expression mef2a factor mads-box mef2b expressed human chen national library medicine

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
MEF2Ainstance ofis a transcription factor with four specific numbers0.80text
Binstance ofis a transcription factor with four specific numbers0.80text
Cinstance ofis a transcription factor with four specific numbers0.80text
and Dinstance ofis a transcription factor with four specific numbers0.80text
Mef2related to Additional InformationMyocyte Enhancer Factor0.60section
Mef2related to Additional InformationMEF2A0.60section
Mef2related to Additional InformationEach MEF20.60section
Mef2related to Additional InformationChen0.60section
Mef2related to Additional InformationBlack0.60section
Mef2related to Additional InformationBoth0.60section
Mef2related to Additional InformationKaramboulas0.60section
Mef2related to Additional InformationThe Type-I0.60section

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    Min side: 3
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