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GATA4

Transcription factor GATA-4 is a protein that in humans is encoded by the GATA4 gene.

Interactions, Function & Clinical relevance

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Interactions

6 related topics

Function

4 related topics

Clinical relevance

1 related topics

Overview

2 related topics

Key facts & relationships

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Aliases
GATA4, GATA binding protein 4, ASD2, TACHD, VSD1, TOF
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2M9W
Band
8p23.1 · 14 D1|14 33.24 cM
Bgee
right auricle of heart · left ventricle · duodenum · apex of heart · left ovary
BioGPS
More reference expression data
Chr.
Chromosome 8 (human) · Chromosome 14 (mouse)

Topics to explore

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Overview

Function

Interactions

Clinical relevance

Advanced semantic analysis

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Map overview Semantic statistics

GATA4

Nodes18
Edges17
Triples171
Avg. degree1.89
Density0.111111
Components1

How this topic connects Entity context

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GATA4

Top relations

Gene ontology · 68
GATA4 → anatomical structure formation involved in morphogenesis, animal organ morphogenesis, aortic valve morphogenesis, atrial septum morphogenesis, atrial septum primum morphogenesis, atrial septum secundum morphogenesis, atrioventricular valve formation, blood coagulation, cardiac muscle cell differentiation, cardiac muscle tissue development, cardiac muscle tissue regeneration, cardiac right ventricle morphogenesis, cardiac ventricle morphogenesis, cell development, cell growth involved in cardiac muscle cell development, cell-cell signaling, cellular response to glucose stimulus, chromatin binding, cis-regulatory region sequence-specific DNA binding, co-SMAD binding
Bgee · 19
GATA4 → apex of heart, body of pancreas, duodenum, epithelium of stomach, germinal epithelium, Gonadal ridge, granulosa cell of ovary, left coronary artery, left ovary, left ventricle, Leydig cell, mucous cell of stomach, pyloric antrum, right auricle of heart, right coronary artery, right ovary, right testis, theca folliculi, yolk sac
RNA expression pattern · 19
GATA4 → apex of heart, body of pancreas, duodenum, epithelium of stomach, germinal epithelium, Gonadal ridge, granulosa cell of ovary, left coronary artery, left ovary, left ventricle, Leydig cell, mucous cell of stomach, pyloric antrum, right auricle of heart, right coronary artery, right ovary, right testis, theca folliculi, yolk sac
related to External links · 13
GATA4 → GATA-4, Medicine, Medicine Medical Subject Headings, MeSH, National Library, Overview, P43694, PDB, PDBe-KB, This, Transcription, UniProt, United States National Library
related to Atrioventricular valve formation · 9
GATA4 → AV, E12, EMT, Endocardial, Erbb3, Erk, GATA4-null, Their, This
related to Interactions · 8
GATA4 → Erbb3, FOG-1, FOG-2, HAND2, HDAC2, NKX2-5, Serum, TBX5
related to Function · 7
GATA4 → As, GATA, Members, Mutations, Nkx2-5, Tbx5, This
related to Clinical relevance · 4
GATA4 → Atrial, Fallot, Mutations, South Indian
Band · 2
GATA4 → 14 D1|14 33.24 cM, 8p23.1
Chr. · 2
GATA4 → Chromosome 14 (mouse), Chromosome 8 (human)

Important terminology Word statistics

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Important terminology

gene cardiac transcription factor human bp development chr protein band function also heart formation chromosome ventricular mutations defects gata location

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
GATA4AliasesGATA4, GATA binding protein 4, ASD2, TACHD, VSD1, TOF1.00infobox
GATA4Available structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2M9W1.00infobox
GATA4Band8p23.11.00infobox
GATA4Band14 D1|14 33.24 cM1.00infobox
GATA4Bgeeright auricle of heart1.00infobox
GATA4Bgeeleft ventricle1.00infobox
GATA4Bgeeduodenum1.00infobox
GATA4Bgeeapex of heart1.00infobox
GATA4Bgeeleft ovary1.00infobox
GATA4Bgeeright coronary artery1.00infobox
GATA4Bgeeright ovary1.00infobox
GATA4Bgeebody of pancreas1.00infobox
GATA4Bgeeleft coronary artery1.00infobox
GATA4Bgeeright testis1.00infobox
GATA4Bgeeepithelium of stomach1.00infobox
GATA4Bgeegerminal epithelium1.00infobox
GATA4Bgeepyloric antrum1.00infobox
GATA4Bgeegranulosa cell of ovary1.00infobox
GATA4Bgeemucous cell of stomach1.00infobox
GATA4BgeeGonadal ridge1.00infobox
GATA4BgeeLeydig cell1.00infobox
GATA4Bgeetheca folliculi1.00infobox
GATA4Bgeeyolk sac1.00infobox
GATA4BioGPSMore reference expression data1.00infobox
GATA4Chr.Chromosome 8 (human)1.00infobox
GATA4Chr.Chromosome 14 (mouse)1.00infobox
GATA4DatabasesNCBI: entry; OMA: entry1.00infobox
GATA4End11,760,002 bp1.00infobox
GATA4End63,509,141 bp1.00infobox
GATA4EnsemblENSG00000136574 ENSG000002851091.00infobox

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