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In the field of molecular biology, the pregnane X receptor (PXR), also known as the steroid and xenobiotic sensing nuclear receptor (SXR) or nuclear receptor subfamily 1, group I, member 2 (NR1I2) is a protein that in humans is encoded by the NR1I2 (nuclear Receptor subfamily 1, group I, member 2) gene.
Ligands, Function & Mechanism
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pxr receptor gene nuclear bp chr human band chromosome nr1i2 also expression location function cyp3a4 protein mouse ii molecular steroid
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| Pregnane X receptor | Aliases | NR1I2, BXR, ONR1, PAR, PAR1, PAR2, PARq, PRR, PXR, SAR, SXR, nuclear receptor subfamily 1 group I member 2 | 1.00 | infobox |
| Pregnane X receptor | Available structures | Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1ILG, 1ILH, 1M13, 1NRL, 1SKX, 2O9I, 2QNV, 3CTB, 3HVL, 3R8D, 4J5W, 4J5X, 4NY9, 4S0S, 4S0T, 4XHD, 4X1F, 4X1G,… | 1.00 | infobox |
| Pregnane X receptor | Band | 3q13.33 | 1.00 | infobox |
| Pregnane X receptor | Band | 16|16 B3 | 1.00 | infobox |
| Pregnane X receptor | Bgee | right lobe of liver | 1.00 | infobox |
| Pregnane X receptor | Bgee | jejunal mucosa | 1.00 | infobox |
| Pregnane X receptor | Bgee | mucosa of transverse colon | 1.00 | infobox |
| Pregnane X receptor | Bgee | duodenum | 1.00 | infobox |
| Pregnane X receptor | Bgee | rectum | 1.00 | infobox |
| Pregnane X receptor | Bgee | mucosa of ileum | 1.00 | infobox |
| Pregnane X receptor | Bgee | mucosa of sigmoid colon | 1.00 | infobox |
| Pregnane X receptor | Bgee | gallbladder | 1.00 | infobox |
| Pregnane X receptor | Bgee | cecum | 1.00 | infobox |
| Pregnane X receptor | Bgee | appendix | 1.00 | infobox |
| Pregnane X receptor | Bgee | jejunum | 1.00 | infobox |
| Pregnane X receptor | Bgee | crypt of lieberkuhn of small intestine | 1.00 | infobox |
| Pregnane X receptor | Bgee | colon | 1.00 | infobox |
| Pregnane X receptor | Bgee | left colon | 1.00 | infobox |
| Pregnane X receptor | Bgee | left lobe of liver | 1.00 | infobox |
| Pregnane X receptor | Bgee | ileum | 1.00 | infobox |
| Pregnane X receptor | Bgee | female urethra | 1.00 | infobox |
| Pregnane X receptor | Bgee | lumbar subsegment of spinal cord | 1.00 | infobox |
| Pregnane X receptor | Bgee | intestinal villus | 1.00 | infobox |
| Pregnane X receptor | BioGPS | More reference expression data | 1.00 | infobox |
| Pregnane X receptor | Chr. | Chromosome 3 (human) | 1.00 | infobox |
| Pregnane X receptor | Chr. | Chromosome 16 (mouse) | 1.00 | infobox |
| Pregnane X receptor | Databases | NCBI: entry; OMA: entry | 1.00 | infobox |
| Pregnane X receptor | End | 119,818,487 bp | 1.00 | infobox |
| Pregnane X receptor | End | 38,115,186 bp | 1.00 | infobox |
| Pregnane X receptor | Ensembl | ENSG00000144852 | 1.00 | infobox |
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