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Interferon regulatory factor 4 (IRF4) also known as MUM1 is a protein that in humans is encoded by the IRF4 gene. IRF4 functions as a key regulatory transcription factor in the development of human immune cells. The expression of IRF4 is essential for the differentiation of T lymphocytes and B lymphocytes as well as certain myeloid cells. Dysregulation…
Immune cell development, Overview & Clinical significance
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cells expression differentiation factor gene plasma development also transcription regulatory human cell irf8 essential bp chromosome chr band immune myeloid
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| IRF4 | Aliases | IRF4, LSIRF, MUM1, NF-EM5, SHEP8, interferon regulatory factor 4 | 1.00 | infobox |
| IRF4 | Available structures | Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2DLL | 1.00 | infobox |
| IRF4 | Band | 6p25.3 | 1.00 | infobox |
| IRF4 | Band | 13|13 A3.2 | 1.00 | infobox |
| IRF4 | Bgee | lymph node | 1.00 | infobox |
| IRF4 | Bgee | canal of the cervix | 1.00 | infobox |
| IRF4 | Bgee | appendix | 1.00 | infobox |
| IRF4 | Bgee | bone marrow cell | 1.00 | infobox |
| IRF4 | Bgee | cartilage tissue | 1.00 | infobox |
| IRF4 | Bgee | spleen | 1.00 | infobox |
| IRF4 | Bgee | epithelium of colon | 1.00 | infobox |
| IRF4 | Bgee | ectocervix | 1.00 | infobox |
| IRF4 | Bgee | rectum | 1.00 | infobox |
| IRF4 | Bgee | superficial temporal artery | 1.00 | infobox |
| IRF4 | Bgee | mesenteric lymph nodes | 1.00 | infobox |
| IRF4 | Bgee | blood | 1.00 | infobox |
| IRF4 | Bgee | subcutaneous adipose tissue | 1.00 | infobox |
| IRF4 | Bgee | granulocyte | 1.00 | infobox |
| IRF4 | Bgee | brown adipose tissue | 1.00 | infobox |
| IRF4 | Bgee | mammary gland | 1.00 | infobox |
| IRF4 | Bgee | submandibular gland | 1.00 | infobox |
| IRF4 | Bgee | bone marrow | 1.00 | infobox |
| IRF4 | Bgee | embryo | 1.00 | infobox |
| IRF4 | BioGPS | More reference expression data | 1.00 | infobox |
| IRF4 | Chr. | Chromosome 6 (human) | 1.00 | infobox |
| IRF4 | Chr. | Chromosome 13 (mouse) | 1.00 | infobox |
| IRF4 | Databases | NCBI: entry; OMA: entry | 1.00 | infobox |
| IRF4 | End | 411,443 bp | 1.00 | infobox |
| IRF4 | End | 30,950,959 bp | 1.00 | infobox |
| IRF4 | Ensembl | ENSG00000137265 | 1.00 | infobox |
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