PRDM1

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PRDM1 topic overview

The analysis highlights Function, Clinical significance and Overview as prominent areas in the source structure around PRDM1.

Related topics: 52
Source areas: 3
Connected nodes: 55
Extracted relationships: 149
Concept neighborhoods: 15
Bridge connections: 55

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Function · 38 topics

Overview · 8 topics

Clinical significance · 6 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases: PRDM1, BLIMP1, PRDI-BF1, PR domain 1, PR/SET domain 1
Available structures: Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes3DAL
Band: 6q21 · 10 B2|10 23.24 cM
Bgee: epithelium of colon · oral cavity · mucosa of pharynx · stromal cell of endometrium · rectum
BioGPS: More reference expression data
Chr.: Chromosome 6 (human) · Chromosome 10 (mouse)

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How PRDM1 connects Entity context

The extracted context around PRDM1 shows recurring relationship patterns in the source. For example, PRDM1 → adaptive immune response, aorta development, artery morphogenesis, cardiac septum development, cell fate commitment, chromatin DNA binding, coronary vasculature development, cytoplasm, DNA binding, DNA-binding transcription factor activity, DNA-binding transcription factor activity, RNA polymerase II-specific, DNA-binding transcription repressor activity, RNA polymerase II-specific, embryonic placenta development, eye photoreceptor cell development, germ cell development, heart valve development, histone deacetylase binding, immune system process, in utero embryonic development, innate immune response Another extracted example is PRDM1 → blood, bone marrow cell, decidua, epithelium of colon, esophagus, gastrula, hair follicle, lip, migratory enteric neural crest cell, mucosa of pharynx, oral cavity, otic placode, otic vesicle, rectum, skin of back, skin of thigh, stromal cell of endometrium, superficial temporal artery, vagina, zygote. Use these groups to spot repeated connection types before inspecting the individual relationships.

Top relations

Gene ontology · 51

PRDM1 → adaptive immune response, aorta development, artery morphogenesis, cardiac septum development, cell fate commitment, chromatin DNA binding, coronary vasculature development, cytoplasm, DNA binding, DNA-binding transcription factor activity, DNA-binding transcription factor activity, RNA polymerase II-specific, DNA-binding transcription repressor activity, RNA polymerase II-specific, embryonic placenta development, eye photoreceptor cell development, germ cell development, heart valve development, histone deacetylase binding, immune system process, in utero embryonic development, innate immune response

Bgee · 20

PRDM1 → blood, bone marrow cell, decidua, epithelium of colon, esophagus, gastrula, hair follicle, lip, migratory enteric neural crest cell, mucosa of pharynx, oral cavity, otic placode, otic vesicle, rectum, skin of back, skin of thigh, stromal cell of endometrium, superficial temporal artery, vagina, zygote

RNA expression pattern · 20

related to Diseases · 11

PRDM1 → Another GWAS, BLIMP-1, CTSS, GWAS, Hodgkin, IBD, IL-6, Interleukin-6, RA, SLE, SNPs

related to T cells · 10

PRDM1 → BLIMP-1, IL-2, Specifically, T-cell, T-cells, T-helper, Tc, Th, Th1, Th17

related to External links · 6

PRDM1 → FactorBookPRDM1 This, Medicine, Medicine Medical Subject Headings, MeSH, National Library, United States National Library

Band · 2

PRDM1 → 10 B2|10 23.24 cM, 6q21

Chr. · 2

PRDM1 → Chromosome 10 (mouse), Chromosome 6 (human)

End · 2

PRDM1 → 106,109,939 bp, 44,404,497 bp

Aliases · 1

PRDM1 → PRDM1, BLIMP1, PRDI-BF1, PR domain 1, PR/SET domain 1

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

blimp-1 cells cell expression immune differentiation gene human bp plasma chromosome macrophages chr band also protein development transcription response osteoclasts

PRDM1 relationships Subject–Predicate–Object triples

TTTA extracted 149 structured relationships around PRDM1. Examples in this analysis include PRDM1 → Aliases → PRDM1, BLIMP1, PRDI-BF1, PR domain 1, PR/SET domain 1 and PRDM1 → Available structures → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes3DAL. The table shows each extracted connection, where it came from and its confidence.

Subject	Predicate	Object	Confidence	Src
PRDM1	Aliases	PRDM1, BLIMP1, PRDI-BF1, PR domain 1, PR/SET domain 1	1.00	infobox
PRDM1	Available structures	Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes3DAL	1.00	infobox
PRDM1	Band	6q21	1.00	infobox
PRDM1	Band	10 B2\|10 23.24 cM	1.00	infobox
PRDM1	Bgee	epithelium of colon	1.00	infobox
PRDM1	Bgee	oral cavity	1.00	infobox
PRDM1	Bgee	mucosa of pharynx	1.00	infobox
PRDM1	Bgee	stromal cell of endometrium	1.00	infobox
PRDM1	Bgee	rectum	1.00	infobox
PRDM1	Bgee	skin of thigh	1.00	infobox
PRDM1	Bgee	blood	1.00	infobox
PRDM1	Bgee	vagina	1.00	infobox
PRDM1	Bgee	bone marrow cell	1.00	infobox
PRDM1	Bgee	superficial temporal artery	1.00	infobox
PRDM1	Bgee	gastrula	1.00	infobox
PRDM1	Bgee	decidua	1.00	infobox
PRDM1	Bgee	otic placode	1.00	infobox
PRDM1	Bgee	zygote	1.00	infobox
PRDM1	Bgee	otic vesicle	1.00	infobox
PRDM1	Bgee	migratory enteric neural crest cell	1.00	infobox
PRDM1	Bgee	lip	1.00	infobox
PRDM1	Bgee	skin of back	1.00	infobox
PRDM1	Bgee	esophagus	1.00	infobox
PRDM1	Bgee	hair follicle	1.00	infobox
PRDM1	BioGPS	More reference expression data	1.00	infobox
PRDM1	Chr.	Chromosome 6 (human)	1.00	infobox
PRDM1	Chr.	Chromosome 10 (mouse)	1.00	infobox
PRDM1	Databases	NCBI: entry; OMA: entry	1.00	infobox
PRDM1	End	106,109,939 bp	1.00	infobox
PRDM1	End	44,404,497 bp	1.00	infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around PRDM1 bring nearby vocabulary together. In this analysis, examples include Protein, Human and Location. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

PRDM1
- Protein
- Human
- Location
- Bp
- Chr
- Transcription
- Cell
- Expressed
- Mouse
- Repressor
- Signaling
- Activation
prdm1
- Protein
- Human
- Location
- Bp
- Chr
- Transcription
- Cell
- Expressed
- Mouse
- Repressor
- Signaling
- Activation
hematopoietic stem cells
- Plasma
- Expression
- Production
- Also
- Osteoclasts
- Proliferation
- Immune
- Cell
- Exhausted
- Plays
- Germ
- Location
plasma b cells
- Plasma
- Differentiate
- Protein
- Response
- Expression
- Production
- Also
- Differentiation
- Osteoclasts
- Proliferation
- Cell
- Dcs
dendritic cells (dcs)
- Macrophages
- Development
- Role
- Plasma
- Plays
- Expression
- Production
- Osteoclasts
- Also
- Proliferation
- Immune
- Cell
nk cells
- Plasma
- Expression
- Production
- Also
- Osteoclasts
- Proliferation
- Immune
- Cell
- Exhausted
- Plays
- Germ
- Location
germ cell
- Mouse
- Repressor
- Proliferation
- Differentiation
- Gene
- Germ
- Macrophages
- Transcription
- Prdm1
- Signaling
- Location
- System
stem cells
- Plasma
- Expression
- Production
- Also
- Osteoclasts
- Proliferation
- Immune
- Cell
- Exhausted
- Plays
- Germ
- Location

Connections between topic areas Semantic bridges

For PRDM1, one of the stronger structural bridges in this analysis connects PRDM1 with Function. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3

PRDM1 — Function · splits 17 ⟂ 39

PRDM1 — Overview · splits 47 ⟂ 9

PRDM1 — Clinical significance · splits 49 ⟂ 7

Map overview Semantic statistics

PRDM1

Nodes56

Edges55

Triples149

Avg. degree1.96

Density0.035714

Components1

Source & methodology

TTTA analyzes the structure around PRDM1 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Function, Clinical significance & Overview, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — PRDM1 · EN edition · Analysis: TopicsToTalkAbout