PRDM1

Use the mouse wheel or two fingers (on touchscreens) to zoom in and out of the map.

Export map as:

Research this topic

Explore the main themes, entities and connections around PRDM1. Start with the topic map, then use the sections below for research and deeper semantic analysis.

Explore this topic

Start with a few of the strongest sections from the source topic. These are research directions, not a list of keywords you must use.

Function

Beta-interferon (IFN-β)IRF1 NFκB TNF-R NLRP12

38 related topics

Clinical significance

GWAS Rheumatoid arthritis (RA)Interleukin-6 Cathepsin S Inflammatory bowel disease (IBD)

6 related topics

Overview

Protein Hematopoietic stem cells Plasma B cells Exhausted T-cells Dendritic cells (DCs)

8 related topics

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases: PRDM1, BLIMP1, PRDI-BF1, PR domain 1, PR/SET domain 1
Available structures: Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes3DAL
Band: 6q21 · 10 B2|10 23.24 cM
Bgee: epithelium of colon · oral cavity · mucosa of pharynx · stromal cell of endometrium · rectum
BioGPS: More reference expression data
Chr.: Chromosome 6 (human) · Chromosome 10 (mouse)

Topics to explore

Browse the full topic structure. Each item opens a new analysis centered on that subject.

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

Map overview Semantic statistics

Nodes56

Edges55

Triples149

Avg. degree1.96

Density0.035714

Components1

How this topic connects Entity context

See the strongest relationship patterns around the current topic before diving into the raw triples.

PRDM1

Top relations

Gene ontology · 51

PRDM1 → adaptive immune response, aorta development, artery morphogenesis, cardiac septum development, cell fate commitment, chromatin DNA binding, coronary vasculature development, cytoplasm, DNA binding, DNA-binding transcription factor activity, DNA-binding transcription factor activity, RNA polymerase II-specific, DNA-binding transcription repressor activity, RNA polymerase II-specific, embryonic placenta development, eye photoreceptor cell development, germ cell development, heart valve development, histone deacetylase binding, immune system process, in utero embryonic development, innate immune response

Bgee · 20

PRDM1 → blood, bone marrow cell, decidua, epithelium of colon, esophagus, gastrula, hair follicle, lip, migratory enteric neural crest cell, mucosa of pharynx, oral cavity, otic placode, otic vesicle, rectum, skin of back, skin of thigh, stromal cell of endometrium, superficial temporal artery, vagina, zygote

RNA expression pattern · 20

related to Diseases · 11

PRDM1 → Another GWAS, BLIMP-1, CTSS, GWAS, Hodgkin, IBD, IL-6, Interleukin-6, RA, SLE, SNPs

related to T cells · 10

PRDM1 → BLIMP-1, IL-2, Specifically, T-cell, T-cells, T-helper, Tc, Th, Th1, Th17

related to External links · 6

PRDM1 → FactorBookPRDM1 This, Medicine, Medicine Medical Subject Headings, MeSH, National Library, United States National Library

Band · 2

PRDM1 → 10 B2|10 23.24 cM, 6q21

Chr. · 2

PRDM1 → Chromosome 10 (mouse), Chromosome 6 (human)

End · 2

PRDM1 → 106,109,939 bp, 44,404,497 bp

Aliases · 1

PRDM1 → PRDM1, BLIMP1, PRDI-BF1, PR domain 1, PR/SET domain 1

Important terminology Word statistics

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

blimp-1 cells cell expression immune differentiation gene human bp plasma chromosome macrophages chr band also protein development transcription response osteoclasts

Entity relationships Subject–Predicate–Object triples

Subject	Predicate	Object	Confidence	Src
PRDM1	Aliases	PRDM1, BLIMP1, PRDI-BF1, PR domain 1, PR/SET domain 1	1.00	infobox
PRDM1	Available structures	Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes3DAL	1.00	infobox
PRDM1	Band	6q21	1.00	infobox
PRDM1	Band	10 B2\|10 23.24 cM	1.00	infobox
PRDM1	Bgee	epithelium of colon	1.00	infobox
PRDM1	Bgee	oral cavity	1.00	infobox
PRDM1	Bgee	mucosa of pharynx	1.00	infobox
PRDM1	Bgee	stromal cell of endometrium	1.00	infobox
PRDM1	Bgee	rectum	1.00	infobox
PRDM1	Bgee	skin of thigh	1.00	infobox
PRDM1	Bgee	blood	1.00	infobox
PRDM1	Bgee	vagina	1.00	infobox
PRDM1	Bgee	bone marrow cell	1.00	infobox
PRDM1	Bgee	superficial temporal artery	1.00	infobox
PRDM1	Bgee	gastrula	1.00	infobox
PRDM1	Bgee	decidua	1.00	infobox
PRDM1	Bgee	otic placode	1.00	infobox
PRDM1	Bgee	zygote	1.00	infobox
PRDM1	Bgee	otic vesicle	1.00	infobox
PRDM1	Bgee	migratory enteric neural crest cell	1.00	infobox
PRDM1	Bgee	lip	1.00	infobox
PRDM1	Bgee	skin of back	1.00	infobox
PRDM1	Bgee	esophagus	1.00	infobox
PRDM1	Bgee	hair follicle	1.00	infobox
PRDM1	BioGPS	More reference expression data	1.00	infobox
PRDM1	Chr.	Chromosome 6 (human)	1.00	infobox
PRDM1	Chr.	Chromosome 10 (mouse)	1.00	infobox
PRDM1	Databases	NCBI: entry; OMA: entry	1.00	infobox
PRDM1	End	106,109,939 bp	1.00	infobox
PRDM1	End	44,404,497 bp	1.00	infobox

Related concept clusters Concept neighborhoods

These clusters group vocabulary that occurs around closely connected concepts in the source material.

Connections between topic areas Semantic bridges

Bridges can reveal useful research angles that are easy to miss in a flat list of related terms.

Min side: 3