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IKZF3: Function, Interactions & Overview

Zinc finger protein Aiolos, also known as Ikaros family zinc finger protein 3, is a protein encoded in humans by the IKZF3 gene.

Language: English [EN]
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IKZF3 topic overview

The analysis highlights Function, Interactions and Overview as prominent areas in the source structure around IKZF3.

Related topics
10
Source areas
3
Connected nodes
13
Extracted relationships
89
Concept neighborhoods
8
Bridge connections
13

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Function · 5 topics
Interactions · 3 topics
Overview · 2 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases
IKZF3, AIO, AIOLOS, ZNFN1A3, IKAROS family zinc finger 3, IMD84
Band
17q12-q21.1 · 11|11 D
Bgee
granulocyte · lymph node · epithelium of nasopharynx · bone marrow cell · thymus
BioGPS
More reference expression data
Chr.
Chromosome 17 (human) · Chromosome 11 (mouse)
Databases
NCBI: entry; OMA: entry

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Function

Interactions

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How IKZF3 connects Entity context

The extracted context around IKZF3 shows recurring relationship patterns in the source. For example, IKZF3 → B cell activation, cytoplasm, cytosol, DNA binding, DNA-binding transcription activator activity, RNA polymerase II-specific, DNA-binding transcription factor activity, DNA-binding transcription factor activity, RNA polymerase II-specific, identical protein binding, mesoderm development, metal ion binding, nucleic acid binding, nucleoplasm, nucleus, plasma membrane, positive regulation of transcription by RNA polymerase II, protein binding, protein heterodimerization activity, protein homodimerization activity, regulation of apoptotic process, regulation of B cell differentiation Another extracted example is IKZF3 → appendix, blood, bone marrow cell, epithelium of nasopharynx, female urethra, granulocyte, lumbar subsegment of spinal cord, lymph node, mesenteric lymph nodes, spleen, subcutaneous adipose tissue, submandibular gland, superficial temporal artery, thymus, tonsil, transitional epithelium of urinary bladder. Use these groups to spot repeated connection types before inspecting the individual relationships.

IKZF3

Top relations

Gene ontology · 29
IKZF3 → B cell activation, cytoplasm, cytosol, DNA binding, DNA-binding transcription activator activity, RNA polymerase II-specific, DNA-binding transcription factor activity, DNA-binding transcription factor activity, RNA polymerase II-specific, identical protein binding, mesoderm development, metal ion binding, nucleic acid binding, nucleoplasm, nucleus, plasma membrane, positive regulation of transcription by RNA polymerase II, protein binding, protein heterodimerization activity, protein homodimerization activity, regulation of apoptotic process, regulation of B cell differentiation
Bgee · 16
IKZF3 → appendix, blood, bone marrow cell, epithelium of nasopharynx, female urethra, granulocyte, lumbar subsegment of spinal cord, lymph node, mesenteric lymph nodes, spleen, subcutaneous adipose tissue, submandibular gland, superficial temporal artery, thymus, tonsil, transitional epithelium of urinary bladder
RNA expression pattern · 16
IKZF3 → appendix, blood, bone marrow cell, epithelium of nasopharynx, female urethra, granulocyte, lumbar subsegment of spinal cord, lymph node, mesenteric lymph nodes, spleen, subcutaneous adipose tissue, submandibular gland, superficial temporal artery, thymus, tonsil, transitional epithelium of urinary bladder
related to External links · 6
IKZF3 → Medicine, Medicine Medical Subject Headings, MeSH, National Library, This, United States National Library
Band · 2
IKZF3 → 11|11 D, 17q12-q21.1
Chr. · 2
IKZF3 → Chromosome 11 (mouse), Chromosome 17 (human)
End · 2
IKZF3 → 39,864,312 bp, 98,436,857 bp
related to Interactions · 2
IKZF3 → BCL2-like, HRAS
Aliases · 1
IKZF3 → IKZF3, AIO, AIOLOS, ZNFN1A3, IKAROS family zinc finger 3, IMD84
BioGPS · 1
IKZF3 → More reference expression data

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

gene bp human ikaros chr band aiolos chromosome 17 protein family regulation location lymphocyte mouse transcription zinc finger function external

IKZF3 relationships Subject–Predicate–Object triples

TTTA extracted 89 structured relationships around IKZF3. Examples in this analysis include IKZF3 → Aliases → IKZF3, AIO, AIOLOS, ZNFN1A3, IKAROS family zinc finger 3, IMD84 and IKZF3 → Band → 17q12-q21.1. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
IKZF3AliasesIKZF3, AIO, AIOLOS, ZNFN1A3, IKAROS family zinc finger 3, IMD841.00infobox
IKZF3Band17q12-q21.11.00infobox
IKZF3Band11|11 D1.00infobox
IKZF3Bgeegranulocyte1.00infobox
IKZF3Bgeelymph node1.00infobox
IKZF3Bgeeepithelium of nasopharynx1.00infobox
IKZF3Bgeebone marrow cell1.00infobox
IKZF3Bgeethymus1.00infobox
IKZF3Bgeespleen1.00infobox
IKZF3Bgeeblood1.00infobox
IKZF3Bgeetonsil1.00infobox
IKZF3Bgeesuperficial temporal artery1.00infobox
IKZF3Bgeeappendix1.00infobox
IKZF3Bgeemesenteric lymph nodes1.00infobox
IKZF3Bgeelumbar subsegment of spinal cord1.00infobox
IKZF3Bgeefemale urethra1.00infobox
IKZF3Bgeesubcutaneous adipose tissue1.00infobox
IKZF3Bgeesubmandibular gland1.00infobox
IKZF3Bgeetransitional epithelium of urinary bladder1.00infobox
IKZF3BioGPSMore reference expression data1.00infobox
IKZF3Chr.Chromosome 17 (human)1.00infobox
IKZF3Chr.Chromosome 11 (mouse)1.00infobox
IKZF3DatabasesNCBI: entry; OMA: entry1.00infobox
IKZF3End39,864,312 bp1.00infobox
IKZF3End98,436,857 bp1.00infobox
IKZF3EnsemblENSG000001614051.00infobox
IKZF3Entrez228061.00infobox
IKZF3External IDsOMIM: 606221; MGI: 1342542; GeneCards: IKZF31.00infobox
IKZF3Gene location (Human)Gene location (Human)Chr.Chromosome 17 (human)Band17q12-q21.1Start39,757,718 bpEnd39,864,312 bp1.00infobox
IKZF3Gene location (Mouse)Gene location (Mouse)Chr.Chromosome 11 (mouse)Band11|11 DStart98,355,728 bpEnd98,436,857 bp1.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around IKZF3 bring nearby vocabulary together. In this analysis, examples include Protein, Human and Function. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • IKZF3
    • Protein
    • Human
    • Function
    • Zinc
    • Gene
    • Location
    • Chromosome
    • Bp
    • Chr
    • External
    • Interactions
    • Known
  • ikzf3
    • Protein
    • Human
    • Function
    • Zinc
    • Gene
    • Location
    • Chromosome
    • Bp
    • Chr
    • External
    • Interactions
    • Known
  • protein
    • Family
    • Development
    • Ikzf3
    • Ikaros
    • Lymphocyte
    • Transcription
    • Regulation
    • Aiolos
    • Human
    • Also
    • Encoded
    • Gene
  • gene
    • Ikaros
    • Location
    • Chromosome
    • Regulation
    • Bp
    • Chr
    • Human
    • Ikzf3
    • Differentiation
    • End
    • Expression
    • Factor
  • function
    • Location
    • Chromosome
    • External
    • Interactions
    • Reading
    • References
    • Bp
    • Chr
    • Human
    • Ikzf3
    • Development
    • Differentiation
  • transcription factors
    • Lymphocyte
    • Regulation
    • Development
    • Differentiation
    • Factor
    • Proliferation
    • Family
    • Protein
    • Gene
    • Ikaros
    • End
    • Expression
  • lymphocyte
    • Transcription
    • Regulation
    • Development
    • Differentiation
    • Proliferation
    • Protein
    • Mouse
  • interactions
    • Reading
    • References
    • Zinc
    • Location
    • Human

Connections between topic areas Semantic bridges

For IKZF3, one of the stronger structural bridges in this analysis connects IKZF3 with Function. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
IKZF3Function · splits 8 ⟂ 6
IKZF3Interactions · splits 10 ⟂ 4
IKZF3Overview · splits 11 ⟂ 3

Map overview Semantic statistics

IKZF3

Nodes14
Edges13
Triples89
Avg. degree1.86
Density0.142857
Components1

Source & methodology

TTTA analyzes the structure around IKZF3 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Function, Interactions & Overview, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — IKZF3 · EN edition · Analysis: TopicsToTalkAbout

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