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Interferon regulatory factor 8 (IRF8) also known as interferon consensus sequence-binding protein (ICSBP), is a protein that in humans is encoded by the IRF8 gene. IRF8 is a transcription factor that plays critical roles in the regulation of lineage commitment and in myeloid cell maturation including the decision for a common myeloid progenitor (CMP) to…
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Explore the main themes, entities and connections around IRF8. Start with the topic map, then use the sections below for research and deeper semantic analysis.
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human factor bp regulatory interferon gene also icsbp chr band cells expression chromosome 16 protein myeloid cell transcription location family
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| IRF8 | Aliases | IRF8, H-ICSBP, ICSBP, ICSBP1, IMD32A, IMD32B, IRF-8, interferon regulatory factor 8 | 1.00 | infobox |
| IRF8 | Band | 16q24.1 | 1.00 | infobox |
| IRF8 | Band | 8 E1|8 70.05 cM | 1.00 | infobox |
| IRF8 | Bgee | monocyte | 1.00 | infobox |
| IRF8 | Bgee | lymph node | 1.00 | infobox |
| IRF8 | Bgee | spleen | 1.00 | infobox |
| IRF8 | Bgee | secondary oocyte | 1.00 | infobox |
| IRF8 | Bgee | appendix | 1.00 | infobox |
| IRF8 | Bgee | granulocyte | 1.00 | infobox |
| IRF8 | Bgee | blood | 1.00 | infobox |
| IRF8 | Bgee | epithelium of colon | 1.00 | infobox |
| IRF8 | Bgee | bone marrow | 1.00 | infobox |
| IRF8 | Bgee | rectum | 1.00 | infobox |
| IRF8 | Bgee | Ileal epithelium | 1.00 | infobox |
| IRF8 | Bgee | mesenteric lymph nodes | 1.00 | infobox |
| IRF8 | Bgee | tibiofemoral joint | 1.00 | infobox |
| IRF8 | Bgee | submandibular gland | 1.00 | infobox |
| IRF8 | Bgee | crypt of lieberkuhn of small intestine | 1.00 | infobox |
| IRF8 | Bgee | jejunum | 1.00 | infobox |
| IRF8 | Bgee | stroma of bone marrow | 1.00 | infobox |
| IRF8 | Bgee | subcutaneous adipose tissue | 1.00 | infobox |
| IRF8 | BioGPS | More reference expression data | 1.00 | infobox |
| IRF8 | Chr. | Chromosome 16 (human) | 1.00 | infobox |
| IRF8 | Chr. | Chromosome 8 (mouse) | 1.00 | infobox |
| IRF8 | Databases | NCBI: entry; OMA: entry | 1.00 | infobox |
| IRF8 | End | 85,922,606 bp | 1.00 | infobox |
| IRF8 | End | 121,483,433 bp | 1.00 | infobox |
| IRF8 | Ensembl | ENSG00000140968 | 1.00 | infobox |
| IRF8 | Entrez | 3394 | 1.00 | infobox |
| IRF8 | External IDs | OMIM: 601565; MGI: 96395; GeneCards: IRF8 | 1.00 | infobox |
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Bridges can reveal useful research angles that are easy to miss in a flat list of related terms.