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Nuclear receptor coactivator 1

The nuclear receptor coactivator 1 (NCOA1), also called steroid receptor coactivator-1 (SRC-1), is a transcriptional coregulatory protein that contains several nuclear receptor–interacting domains and possesses intrinsic histone acetyltransferase activity. It is encoded by the gene NCOA1.

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2.3.1.48
Aliases
NCOA1, F-SRC-1, KAT13A, RIP160, SRC1, bHLHe42, bHLHe74, nuclear receptor coactivator 1
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1FM6, 1FM9, 1K74, 1K7L, 1KV6, 1K4W, 1N4H, 1NQ7, 1NRL, 1P8D, 1PZL, 1RDT, 1TFC, 1U3R, 1U3S, 1X76, 1XIU, 1XV9,…
Band
2p23.3 · 12|12 A1.1
Bgee
middle temporal gyrus · middle frontal gyrus · paraflocculus of cerebellum · Brodmann area 23 · entorhinal cortex
BioGPS
More reference expression data

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Nuclear receptor coactivator 1

Nodes27
Edges26
Triples136
Avg. degree1.93
Density0.074074
Components1

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Nuclear receptor coactivator 1

Top relations

Gene ontology · 60
Nuclear receptor coactivator 1 → acyltransferase activity, androgen receptor binding, androgen receptor signaling pathway, aryl hydrocarbon receptor binding, bile acid and bile salt transport, cellular response to hormone stimulus, cellular response to Thyroglobulin triiodothyronine, cerebellum development, cerebral cortex development, chromatin binding, cytoplasm, cytosol, DNA binding, DNA-binding transcription factor activity, RNA polymerase II-specific, enzyme binding, estrogen receptor binding, estrous cycle, hippocampus development, histone acetyltransferase activity, histone H4 acetylation
Bgee · 20
Nuclear receptor coactivator 1 → anterior amygdaloid area, Brodmann area 23, dentate gyrus of hippocampal formation granule cell, endothelial cell, entorhinal cortex, frontal pole, lateral geniculate nucleus, lateral septal nucleus, mammillary body, middle frontal gyrus, middle temporal gyrus, motor neuron, paraflocculus of cerebellum, postcentral gyrus, Region I of hippocampus proper, retinal pigment epithelium, Rostral migratory stream, subiculum, tibialis anterior muscle, ventromedial nucleus
RNA expression pattern · 20
Nuclear receptor coactivator 1 → anterior amygdaloid area, Brodmann area 23, dentate gyrus of hippocampal formation granule cell, endothelial cell, entorhinal cortex, frontal pole, lateral geniculate nucleus, lateral septal nucleus, mammillary body, middle frontal gyrus, middle temporal gyrus, motor neuron, paraflocculus of cerebellum, postcentral gyrus, Region I of hippocampus proper, retinal pigment epithelium, Rostral migratory stream, subiculum, tibialis anterior muscle, ventromedial nucleus
related to Interactions · 7
Nuclear receptor coactivator 1 → Androgen, C-Fos, C-jun, CIITA, CREB-binding, Cyclin D1, Nuclear
related to External links · 4
Nuclear receptor coactivator 1 → Medicine Medical Subject Headings, MeSH, National Library, NURSAC89
Band · 2
Nuclear receptor coactivator 1 → 12|12 A1.1, 2p23.3
Chr. · 2
Nuclear receptor coactivator 1 → Chromosome 12 (mouse), Chromosome 2 (human)
End · 2
Nuclear receptor coactivator 1 → 24,770,702 bp, 4,477,182 bp
2.3.1.48 · 1
Nuclear receptor coactivator 1 → ↗
Aliases · 1
Nuclear receptor coactivator 1 → NCOA1, F-SRC-1, KAT13A, RIP160, SRC1, bHLHe42, bHLHe74, nuclear receptor coactivator 1

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Important terminology

ncoa1 nuclear coactivator bp chr dna human band receptor gene chromosome activity protein location receptors promoter mouse histone acetyltransferase transcription

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Nuclear receptor coactivator 12.3.1.481.00infobox
Nuclear receptor coactivator 1AliasesNCOA1, F-SRC-1, KAT13A, RIP160, SRC1, bHLHe42, bHLHe74, nuclear receptor coactivator 11.00infobox
Nuclear receptor coactivator 1Available structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1FM6, 1FM9, 1K74, 1K7L, 1KV6, 1K4W, 1N4H, 1NQ7, 1NRL, 1P8D, 1PZL, 1RDT, 1TFC, 1U3R, 1U3S, 1X76, 1XIU, 1XV9,…1.00infobox
Nuclear receptor coactivator 1Band2p23.31.00infobox
Nuclear receptor coactivator 1Band12|12 A1.11.00infobox
Nuclear receptor coactivator 1Bgeemiddle temporal gyrus1.00infobox
Nuclear receptor coactivator 1Bgeemiddle frontal gyrus1.00infobox
Nuclear receptor coactivator 1Bgeeparaflocculus of cerebellum1.00infobox
Nuclear receptor coactivator 1BgeeBrodmann area 231.00infobox
Nuclear receptor coactivator 1Bgeeentorhinal cortex1.00infobox
Nuclear receptor coactivator 1Bgeetibialis anterior muscle1.00infobox
Nuclear receptor coactivator 1Bgeepostcentral gyrus1.00infobox
Nuclear receptor coactivator 1Bgeefrontal pole1.00infobox
Nuclear receptor coactivator 1Bgeeendothelial cell1.00infobox
Nuclear receptor coactivator 1BgeeRegion I of hippocampus proper1.00infobox
Nuclear receptor coactivator 1BgeeRostral migratory stream1.00infobox
Nuclear receptor coactivator 1Bgeeretinal pigment epithelium1.00infobox
Nuclear receptor coactivator 1Bgeelateral septal nucleus1.00infobox
Nuclear receptor coactivator 1Bgeedentate gyrus of hippocampal formation granule cell1.00infobox
Nuclear receptor coactivator 1Bgeelateral geniculate nucleus1.00infobox
Nuclear receptor coactivator 1Bgeeanterior amygdaloid area1.00infobox
Nuclear receptor coactivator 1Bgeemotor neuron1.00infobox
Nuclear receptor coactivator 1Bgeeventromedial nucleus1.00infobox
Nuclear receptor coactivator 1Bgeemammillary body1.00infobox
Nuclear receptor coactivator 1Bgeesubiculum1.00infobox
Nuclear receptor coactivator 1BioGPSMore reference expression data1.00infobox
Nuclear receptor coactivator 1Chr.Chromosome 2 (human)1.00infobox
Nuclear receptor coactivator 1Chr.Chromosome 12 (mouse)1.00infobox
Nuclear receptor coactivator 1DatabasesNCBI: entry; OMA: entry1.00infobox
Nuclear receptor coactivator 1End24,770,702 bp1.00infobox

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