PSMD2

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Clinical significance

Ubiquitin–proteasome system Ubiquitination Proteolysis Cell cycle Cell growth

59 related topics

Structure

Proteasome Rpn2 Rpn10 Rpn13

4 related topics

Interactions

Interact TNFRSF1A PSMC1

3 related topics

Overview

Enzyme Gene

2 related topics

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases: PSMD2, P97, RPN1, S2, TRAP2, proteasome 26S subunit, non-ATPase 2, proteasome 26S subunit ubiquitin receptor, non-ATPase 2
Band: 3q27.1 · 16|16 A3
Bgee: secondary oocyte · endothelial cell · stromal cell of endometrium · right testis · gastrocnemius muscle
BioGPS: More reference expression data
Chr.: Chromosome 3 (human) · Chromosome 16 (mouse)
Databases: NCBI: entry; OMA: entry

Topics to explore

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Overview

Structure

Proteasome
Rpn2 PSMD1
Rpn10 PSMD4
Rpn13 ARDM1?action=edit&redlink=1

Interactions

Interact Protein–protein interaction
TNFRSF1A
PSMC1

Advanced semantic analysis

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Map overview Semantic statistics

Nodes73

Edges72

Triples113

Avg. degree1.97

Density0.027397

Components1

How this topic connects Entity context

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PSMD2

Top relations

Gene ontology · 43

PSMD2 → anaphase-promoting complex-dependent catabolic process, antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent, cytosol, endopeptidase activity, enzyme regulator activity, extracellular exosome, extracellular region, Fc-epsilon receptor signaling pathway, ficolin-1-rich granule lumen, interleukin-1-mediated signaling pathway, MAPK cascade, membrane, negative regulation of canonical Wnt signaling pathway, negative regulation of G2/M transition of mitotic cell cycle, neutrophil degranulation, NIK/NF-kappaB signaling, nucleoplasm, nucleus, positive regulation of canonical Wnt signaling pathway, post-translational protein modification

Bgee · 19

PSMD2 → blastocyst, dentate gyrus of hippocampal formation granule cell, endothelial cell, esophagus, gastrocnemius muscle, genital tubercle, glutes, islet of Langerhans, left testis, morula, muscle of thigh, right adrenal gland, right testis, secondary oocyte, spermatocyte, stromal cell of endometrium, tail of embryo, ventricular zone, yolk sac

RNA expression pattern · 19

related to Gene expression · 5

PSMD2 → ATPase, In, The, TNF, Two

Band · 2

PSMD2 → 16|16 A3, 3q27.1

Chr. · 2

PSMD2 → Chromosome 16 (mouse), Chromosome 3 (human)

End · 2

PSMD2 → 184,309,050 bp, 20,482,164 bp

related to Interactions · 2

PSMD2 → PSMC1, TNFRSF1A

Aliases · 1

PSMD2 → PSMD2, P97, RPN1, S2, TRAP2, proteasome 26S subunit, non-ATPase 2, proteasome 26S subunit ubiquitin receptor, non-ATPase 2

BioGPS · 1

PSMD2 → More reference expression data

Important terminology Word statistics

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Important terminology

proteasome protein 19s gene complex regulatory subunit rpn1 base non-atpase human ups bp particle 26s band subunits degradation chromosome chr

Entity relationships Subject–Predicate–Object triples

Subject	Predicate	Object	Confidence	Src
PSMD2	Aliases	PSMD2, P97, RPN1, S2, TRAP2, proteasome 26S subunit, non-ATPase 2, proteasome 26S subunit ubiquitin receptor, non-ATPase 2	1.00	infobox
PSMD2	Band	3q27.1	1.00	infobox
PSMD2	Band	16\|16 A3	1.00	infobox
PSMD2	Bgee	secondary oocyte	1.00	infobox
PSMD2	Bgee	endothelial cell	1.00	infobox
PSMD2	Bgee	stromal cell of endometrium	1.00	infobox
PSMD2	Bgee	right testis	1.00	infobox
PSMD2	Bgee	gastrocnemius muscle	1.00	infobox
PSMD2	Bgee	left testis	1.00	infobox
PSMD2	Bgee	muscle of thigh	1.00	infobox
PSMD2	Bgee	glutes	1.00	infobox
PSMD2	Bgee	islet of Langerhans	1.00	infobox
PSMD2	Bgee	right adrenal gland	1.00	infobox
PSMD2	Bgee	yolk sac	1.00	infobox
PSMD2	Bgee	ventricular zone	1.00	infobox
PSMD2	Bgee	dentate gyrus of hippocampal formation granule cell	1.00	infobox
PSMD2	Bgee	genital tubercle	1.00	infobox
PSMD2	Bgee	blastocyst	1.00	infobox
PSMD2	Bgee	tail of embryo	1.00	infobox
PSMD2	Bgee	esophagus	1.00	infobox
PSMD2	Bgee	spermatocyte	1.00	infobox
PSMD2	Bgee	morula	1.00	infobox
PSMD2	BioGPS	More reference expression data	1.00	infobox
PSMD2	Chr.	Chromosome 3 (human)	1.00	infobox
PSMD2	Chr.	Chromosome 16 (mouse)	1.00	infobox
PSMD2	Databases	NCBI: entry; OMA: entry	1.00	infobox
PSMD2	End	184,309,050 bp	1.00	infobox
PSMD2	End	20,482,164 bp	1.00	infobox
PSMD2	Ensembl	ENSG00000175166	1.00	infobox
PSMD2	Entrez	5708	1.00	infobox

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