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26S proteasome non-ATPase regulatory subunit 2, also as known as 26S Proteasome Regulatory Subunit Rpn1 (systematic nomenclature), is an enzyme that in humans is encoded by the PSMD2 gene.
The analysis highlights Measurement, Clinical significance and Structure as prominent areas in the source structure around PSMD2.
Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.
Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.
High-confidence facts extracted from structured source data. Use them as anchors for further research.
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The extracted context around PSMD2 shows recurring relationship patterns in the source. For example, PSMD2 → anaphase-promoting complex-dependent catabolic process, antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent, cytosol, endopeptidase activity, enzyme regulator activity, extracellular exosome, extracellular region, Fc-epsilon receptor signaling pathway, ficolin-1-rich granule lumen, interleukin-1-mediated signaling pathway, MAPK cascade, membrane, negative regulation of canonical Wnt signaling pathway, negative regulation of G2/M transition of mitotic cell cycle, neutrophil degranulation, NIK/NF-kappaB signaling, nucleoplasm, nucleus, positive regulation of canonical Wnt signaling pathway, post-translational protein modification Another extracted example is PSMD2 → blastocyst, dentate gyrus of hippocampal formation granule cell, endothelial cell, esophagus, gastrocnemius muscle, genital tubercle, glutes, islet of Langerhans, left testis, morula, muscle of thigh, right adrenal gland, right testis, secondary oocyte, spermatocyte, stromal cell of endometrium, tail of embryo, ventricular zone, yolk sac. Use these groups to spot repeated connection types before inspecting the individual relationships.
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proteasome protein 19s gene complex regulatory subunit rpn1 base non-atpase human ups bp particle 26s band subunits degradation chromosome chr
TTTA extracted 111 structured relationships around PSMD2. Examples in this analysis include PSMD2 → Aliases → PSMD2, P97, RPN1, S2, TRAP2, proteasome 26S subunit, non-ATPase 2, proteasome 26S subunit ubiquitin receptor, non-ATPase 2 and PSMD2 → Band → 3q27.1. The table shows each extracted connection, where it came from and its confidence.
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| PSMD2 | Aliases | PSMD2, P97, RPN1, S2, TRAP2, proteasome 26S subunit, non-ATPase 2, proteasome 26S subunit ubiquitin receptor, non-ATPase 2 | 1.00 | infobox |
| PSMD2 | Band | 3q27.1 | 1.00 | infobox |
| PSMD2 | Band | 16|16 A3 | 1.00 | infobox |
| PSMD2 | Bgee | secondary oocyte | 1.00 | infobox |
| PSMD2 | Bgee | endothelial cell | 1.00 | infobox |
| PSMD2 | Bgee | stromal cell of endometrium | 1.00 | infobox |
| PSMD2 | Bgee | right testis | 1.00 | infobox |
| PSMD2 | Bgee | gastrocnemius muscle | 1.00 | infobox |
| PSMD2 | Bgee | left testis | 1.00 | infobox |
| PSMD2 | Bgee | muscle of thigh | 1.00 | infobox |
| PSMD2 | Bgee | glutes | 1.00 | infobox |
| PSMD2 | Bgee | islet of Langerhans | 1.00 | infobox |
| PSMD2 | Bgee | right adrenal gland | 1.00 | infobox |
| PSMD2 | Bgee | yolk sac | 1.00 | infobox |
| PSMD2 | Bgee | ventricular zone | 1.00 | infobox |
| PSMD2 | Bgee | dentate gyrus of hippocampal formation granule cell | 1.00 | infobox |
| PSMD2 | Bgee | genital tubercle | 1.00 | infobox |
| PSMD2 | Bgee | blastocyst | 1.00 | infobox |
| PSMD2 | Bgee | tail of embryo | 1.00 | infobox |
| PSMD2 | Bgee | esophagus | 1.00 | infobox |
| PSMD2 | Bgee | spermatocyte | 1.00 | infobox |
| PSMD2 | Bgee | morula | 1.00 | infobox |
| PSMD2 | BioGPS | More reference expression data | 1.00 | infobox |
| PSMD2 | Chr. | Chromosome 3 (human) | 1.00 | infobox |
| PSMD2 | Chr. | Chromosome 16 (mouse) | 1.00 | infobox |
| PSMD2 | Databases | NCBI: entry; OMA: entry | 1.00 | infobox |
| PSMD2 | End | 184,309,050 bp | 1.00 | infobox |
| PSMD2 | End | 20,482,164 bp | 1.00 | infobox |
| PSMD2 | Ensembl | ENSG00000175166 | 1.00 | infobox |
| PSMD2 | Entrez | 5708 | 1.00 | infobox |
The concept neighborhoods around PSMD2 bring nearby vocabulary together. In this analysis, examples include Chromosome, Expression and Human. Use the clusters to find adjacent concepts and terminology that may deserve separate research.
For PSMD2, one of the stronger structural bridges in this analysis connects PSMD2 with Clinical significance. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.
TTTA analyzes the structure around PSMD2 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Measurement, Clinical significance & Structure, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.
Source: Wikipedia — PSMD2 · EN edition · Analysis: TopicsToTalkAbout
