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26S proteasome non-ATPase regulatory subunit 4, also as known as 26S Proteasome Regulatory Subunit Rpn10 (systematic nomenclature), is an enzyme that in humans is encoded by the PSMD4 gene. This protein is one of the 19 essential subunits that contributes to the complete assembly of 19S proteasome complex.
The analysis highlights Measurement, Clinical significance and Complex assembly as prominent areas in the source structure around PSMD4.
Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.
Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.
High-confidence facts extracted from structured source data. Use them as anchors for further research.
Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.
Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.
The extracted context around PSMD4 shows recurring relationship patterns in the source. For example, PSMD4 → anaphase-promoting complex-dependent catabolic process, antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent, cytosol, Fc-epsilon receptor signaling pathway, identical protein binding, interleukin-1-mediated signaling pathway, MAPK cascade, negative regulation of canonical Wnt signaling pathway, negative regulation of G2/M transition of mitotic cell cycle, NIK/NF-kappaB signaling, nucleoplasm, nucleus, polyubiquitin modification-dependent protein binding, positive regulation of canonical Wnt signaling pathway, post-translational protein modification, proteasome accessory complex, proteasome assembly, proteasome complex, proteasome regulatory particle, base subcomplex, proteasome-mediated ubiquitin-dependent protein catabolic process Another extracted example is PSMD4 → abdominal wall, amygdala, apex of heart, C1 segment, choroid plexus of fourth ventricle, facial motor nucleus, gastrocnemius muscle, left testis, lens, mandibular prominence, maxillary prominence, medial head of gastrocnemius muscle, monocyte, muscle layer of sigmoid colon, muscle of thigh, right frontal lobe, right testis, temporal muscle, yolk sac. Use these groups to spot repeated connection types before inspecting the individual relationships.
Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.
protein proteasome complex gene 19s regulatory base subunit rpn10 subunits human assembly ups bp particle band degradation 26s non-atpase chr
TTTA extracted 108 structured relationships around PSMD4. Examples in this analysis include PSMD4 → Aliases → PSMD4, AF, AF-1, ASF, MCB1, Rpn10, S5A, pUB-R5, proteasome 26S subunit, non-ATPase 4, proteasome 26S subunit ubiquitin receptor, non-ATPase 4 and PSMD4 → Available structures → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1P9C, 1P9D, 1UEL, 1YX4, 1YX5, 1YX6, 2KDE, 2KDF. The table shows each extracted connection, where it came from and its confidence.
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| PSMD4 | Aliases | PSMD4, AF, AF-1, ASF, MCB1, Rpn10, S5A, pUB-R5, proteasome 26S subunit, non-ATPase 4, proteasome 26S subunit ubiquitin receptor, non-ATPase 4 | 1.00 | infobox |
| PSMD4 | Available structures | Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1P9C, 1P9D, 1UEL, 1YX4, 1YX5, 1YX6, 2KDE, 2KDF | 1.00 | infobox |
| PSMD4 | Band | 1q21.3 | 1.00 | infobox |
| PSMD4 | Band | 3 F2.1|3 40.74 cM | 1.00 | infobox |
| PSMD4 | Bgee | apex of heart | 1.00 | infobox |
| PSMD4 | Bgee | left testis | 1.00 | infobox |
| PSMD4 | Bgee | right testis | 1.00 | infobox |
| PSMD4 | Bgee | gastrocnemius muscle | 1.00 | infobox |
| PSMD4 | Bgee | muscle of thigh | 1.00 | infobox |
| PSMD4 | Bgee | right frontal lobe | 1.00 | infobox |
| PSMD4 | Bgee | muscle layer of sigmoid colon | 1.00 | infobox |
| PSMD4 | Bgee | amygdala | 1.00 | infobox |
| PSMD4 | Bgee | C1 segment | 1.00 | infobox |
| PSMD4 | Bgee | monocyte | 1.00 | infobox |
| PSMD4 | Bgee | yolk sac | 1.00 | infobox |
| PSMD4 | Bgee | abdominal wall | 1.00 | infobox |
| PSMD4 | Bgee | facial motor nucleus | 1.00 | infobox |
| PSMD4 | Bgee | mandibular prominence | 1.00 | infobox |
| PSMD4 | Bgee | maxillary prominence | 1.00 | infobox |
| PSMD4 | Bgee | temporal muscle | 1.00 | infobox |
| PSMD4 | Bgee | lens | 1.00 | infobox |
| PSMD4 | Bgee | medial head of gastrocnemius muscle | 1.00 | infobox |
| PSMD4 | Bgee | choroid plexus of fourth ventricle | 1.00 | infobox |
| PSMD4 | BioGPS | More reference expression data | 1.00 | infobox |
| PSMD4 | Chr. | Chromosome 1 (human) | 1.00 | infobox |
| PSMD4 | Chr. | Chromosome 3 (mouse) | 1.00 | infobox |
| PSMD4 | Databases | NCBI: entry; OMA: entry | 1.00 | infobox |
| PSMD4 | End | 151,267,479 bp | 1.00 | infobox |
| PSMD4 | End | 94,949,925 bp | 1.00 | infobox |
| PSMD4 | Ensembl | ENSG00000159352 | 1.00 | infobox |
The concept neighborhoods around PSMD4 bring nearby vocabulary together. In this analysis, examples include Chromosome, Human and Function. Use the clusters to find adjacent concepts and terminology that may deserve separate research.
For PSMD4, one of the stronger structural bridges in this analysis connects PSMD4 with Clinical significance. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.
TTTA analyzes the structure around PSMD4 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Measurement, Clinical significance & Complex assembly, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.
Source: Wikipedia — PSMD4 · EN edition · Analysis: TopicsToTalkAbout