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Semaglutide

Semaglutide is an anti-diabetic medication used for the treatment of type 2 diabetes, and an anti-obesity medication used for weight management. It can be administered by subcutaneous injection or taken orally. It is sold as a generic drug by several drug companies in the Indian and Canadian markets, and worldwide by its originator, Novo Nordisk, under…

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Key facts & relationships

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3D model (JSmol)
Interactive image
AHFS/Drugs.com
Monograph
ATC code
A10BJ06 (WHO)
Bioavailability
89% (Subcutaneous), 1–2% (Oral)
CAS Number
910463-68-2
ChEBI
CHEBI:167574

Topics to explore

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Overview

Medical uses

Contraindications

Adverse effects and safety profile

Structure and pharmacology

Mechanism of action

Manufacturing

History and clinical trials

Society and culture

Research and emerging applications

Advanced semantic analysis

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Map overview Semantic statistics

Semaglutide

Nodes248
Edges247
Triples274
Avg. degree1.99
Density0.008065
Components1

How this topic connects Entity context

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Semaglutide

Top relations

related to Clinical trials and early approvals for diabetes · 34
Semaglutide → Argentina, Canada, Clinical, Drug Administration, European, FDA, HbA1c, Hong Kong, II, In, In June, India, It, January, Japan, May, Mexico, NCT01885208, NCT01930188, NCT02054897
related to Legal status · 20
Semaglutide → April, August, Australia, Canada, Drug Administration, European Union, FDA, In December, In February, In January, January, Japan, March, October, Ozempic, Rybelsus, September, US, US FDA, US Food
related to history · 19
Semaglutide → Daniel, Drucker, GLP-1, GLP-1's, However, In, Jens Juul Holst, Jesper Lau, Joel Habener, Lotte Bjerre Knudsen, Michael Nauck, Novo Nordisk, Paw Bloch, Research, Their, They, This, Thomas Kruse, Warren Alpert Foundation Prize
related to Compounded versions · 16
Semaglutide → As, August, Doustdar, Drug Administration's, FDA, Food, GLP-1, In, January, Novo Nordisk CEO Mike, Ozempic, Rybelsus, The FDA, United States, US, Wegovy
related to Inflammation and oxidative stress · 15
Semaglutide → Consequently, CXCL2, ER, Furthermore, IL-6, In, JNK, NF-κB, NRF2, ROS, S100A8, S100A9, SIRT1, This, TNF-α
related to Central nervous system and appetite regulation · 14
Semaglutide → Acute, AgRP, CART, Furthermore, GLP-1, However, In, It, JAK/STAT, NPY, POMC, PTP1B, SOCS3, This
related to Cellular aging and autophagy · 12
Semaglutide → Additionally, AMPK, Bcl-2, By, FOXO, NF-κB, Pathological, Preclinical, SASP, Senescent, SIRT1, TFEB
related to Adipose tissue and metabolism · 11
Semaglutide → AMPK, ANGPTL4, BAT, In, It, LPL, More, SIRT1, This, UCP1, WAT
related to External links · 10
Semaglutide → Clinical, ClinicalTrials, Heart Disease, MedlinePlus, NCT03574597, Obesity, Patients With Overweight, SELECT, Semaglutide Effects, Stroke
related to Pancreatic and glycemic control · 10
Semaglutide → AMP, AMPK/SIRT1, Beyond, Concurrently, GLP-1, GLUT4, IRS-1, It, PKA, This

Important terminology Word statistics

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Important terminology

diabetes weight generic treatment glp-1 drug novo nordisk wegovy 2026 obesity ozempic us type approved risk people use management health

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Semaglutide3D model (JSmol)Interactive image1.00infobox
SemaglutideAHFS/Drugs.comMonograph1.00infobox
SemaglutideATC codeA10BJ06 (WHO)1.00infobox
SemaglutideBioavailability89% (Subcutaneous), 1–2% (Oral)1.00infobox
SemaglutideCAS Number910463-68-21.00infobox
SemaglutideChEBICHEBI:1675741.00infobox
SemaglutideChemSpider349811341.00infobox
SemaglutideDrugBankDB139281.00infobox
SemaglutideDuration of action63.6 hours1.00infobox
SemaglutideECHA InfoCard100.219.5411.00infobox
SemaglutideElimination half-life7 days1.00infobox
SemaglutideExcretionUrine and feces1.00infobox
SemaglutideFormulaC187H291N45O591.00infobox
SemaglutideKEGGD100251.00infobox
SemaglutideLegal statusAU: S4 (Prescription only)1.00infobox
SemaglutideLegal statusCA: ℞-only / Schedule D1.00infobox
SemaglutideLegal statusUK: POM (Prescription only)1.00infobox
SemaglutideLegal statusUS: ℞-only1.00infobox
SemaglutideLegal statusEU: Rx-only1.00infobox
SemaglutideLegal statusSE: Rx-only1.00infobox
SemaglutideLicense dataUS DailyMed: Semaglutide1.00infobox
SemaglutideMedlinePlusa6180081.00infobox
SemaglutideMetabolismProteolysis1.00infobox
SemaglutideMolar mass4113.641 g·mol−11.00infobox
SemaglutidePregnancy categoryAU: D1.00infobox
SemaglutidePronunciation/sɛmˈæɡlʊtaɪd/ sem-AG-luu-tyde or /ˌsɛməˈɡluːtaɪd/ ⓘ SEM-ə-GLOO-tyde1.00infobox
SemaglutidePubChem CID568433311.00infobox
SemaglutideRoutes of administrationSubcutaneous, oral1.00infobox
SemaglutideTrade namesOzempic, Rybelsus, Wegovy, others1.00infobox
SemaglutideUNII53AXN4NNHX1.00infobox

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