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CXCL2

Chemokine (C-X-C motif) ligand 2 (CXCL2) is a small cytokine belonging to the CXC chemokine family that is also called macrophage inflammatory protein 2-alpha (MIP2-alpha), Growth-regulated protein beta (Gro-beta) and Gro oncogene-2 (Gro-2). CXCL2 is 90% identical in amino acid sequence as a related chemokine, CXCL1. This chemokine is secreted by…

Clinical development & Overview

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Aliases
CXCL2, CINC-2a, GRO2, GROb, MGSA-b, MIP-2a, MIP2, MIP2A, SCYB2, C-X-C motif chemokine ligand 2
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1QNK
Band
4q13.3 · 5 E1|5 44.78 cM
Bgee
mucosa of paranasal sinus · right lobe of liver · vena cava · saphenous vein · cartilage tissue
BioGPS
n/a
Chr.
Chromosome 4 (human) · Chromosome 5 (mouse)

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Overview

Clinical development

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Map overview Semantic statistics

CXCL2

Nodes20
Edges19
Triples88
Avg. degree1.9
Density0.1
Components1

How this topic connects Entity context

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CXCL2

Top relations

Gene ontology · 23
CXCL2 → antimicrobial humoral immune response mediated by antimicrobial peptide, cell chemotaxis, cellular response to lipopolysaccharide, chemokine activity, chemokine-mediated signaling pathway, chemotaxis, CXCR chemokine receptor binding, cytokine activity, cytokine-mediated signaling pathway, defense response, extracellular region, extracellular space, G protein-coupled receptor signaling pathway, immune response, inflammatory response, leukocyte chemotaxis, neutrophil chemotaxis, positive regulation of neutrophil chemotaxis, protein binding, regulation of cell population proliferation
Bgee · 19
CXCL2 → beta cell, cartilage tissue, cumulus cell, embryo, endothelial cell of lymphatic vessel, gastric mucosa, islet of Langerhans, left lobe of liver, lower lobe of lung, mucosa of paranasal sinus, right lobe of liver, saphenous vein, spermatid, spermatocyte, stroma of bone marrow, trachea, upper lobe of left lung, upper lobe of lung, vena cava
RNA expression pattern · 19
CXCL2 → beta cell, cartilage tissue, cumulus cell, embryo, endothelial cell of lymphatic vessel, gastric mucosa, islet of Langerhans, left lobe of liver, lower lobe of lung, mucosa of paranasal sinus, right lobe of liver, saphenous vein, spermatid, spermatocyte, stroma of bone marrow, trachea, upper lobe of left lung, upper lobe of lung, vena cava
related to Clinical development · 4
CXCL2 → CXCR4, Magenta Therapeutics, Phase, This
Band · 2
CXCL2 → 4q13.3, 5 E1|5 44.78 cM
Chr. · 2
CXCL2 → Chromosome 4 (human), Chromosome 5 (mouse)
End · 2
CXCL2 → 74,099,196 bp, 91,040,974 bp
Aliases · 1
CXCL2 → CXCL2, CINC-2a, GRO2, GROb, MGSA-b, MIP-2a, MIP2, MIP2A, SCYB2, C-X-C motif chemokine ligand 2
Available structures · 1
CXCL2 → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1QNK
BioGPS · 1
CXCL2 → n/a

Important terminology Word statistics

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Important terminology

chemokine human bp cells chromosome chr band gene cxcl1 cell location 040 stem cxc also called related chemokines study cxcl3

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
CXCL2AliasesCXCL2, CINC-2a, GRO2, GROb, MGSA-b, MIP-2a, MIP2, MIP2A, SCYB2, C-X-C motif chemokine ligand 21.00infobox
CXCL2Available structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1QNK1.00infobox
CXCL2Band4q13.31.00infobox
CXCL2Band5 E1|5 44.78 cM1.00infobox
CXCL2Bgeemucosa of paranasal sinus1.00infobox
CXCL2Bgeeright lobe of liver1.00infobox
CXCL2Bgeevena cava1.00infobox
CXCL2Bgeesaphenous vein1.00infobox
CXCL2Bgeecartilage tissue1.00infobox
CXCL2Bgeelower lobe of lung1.00infobox
CXCL2Bgeebeta cell1.00infobox
CXCL2Bgeeupper lobe of lung1.00infobox
CXCL2Bgeeupper lobe of left lung1.00infobox
CXCL2Bgeegastric mucosa1.00infobox
CXCL2Bgeeendothelial cell of lymphatic vessel1.00infobox
CXCL2Bgeeleft lobe of liver1.00infobox
CXCL2Bgeespermatocyte1.00infobox
CXCL2Bgeeembryo1.00infobox
CXCL2Bgeespermatid1.00infobox
CXCL2Bgeestroma of bone marrow1.00infobox
CXCL2Bgeeislet of Langerhans1.00infobox
CXCL2Bgeetrachea1.00infobox
CXCL2Bgeecumulus cell1.00infobox
CXCL2BioGPSn/a1.00infobox
CXCL2Chr.Chromosome 4 (human)1.00infobox
CXCL2Chr.Chromosome 5 (mouse)1.00infobox
CXCL2DatabasesNCBI: entry; OMA: entry1.00infobox
CXCL2End74,099,196 bp1.00infobox
CXCL2End91,040,974 bp1.00infobox
CXCL2EnsemblENSG000000810411.00infobox

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