Toll-like receptor 2

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Explore the main themes, entities and connections around Toll-like receptor 2. Start with the topic map, then use the sections below for research and deeper semantic analysis.

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Mechanism

Bacterial Fungal Viral Endogenous Endosomes

27 related topics

Expression

Microglia Schwann cells Monocytes B cells T cells

20 related topics

Background

Antibodies Cross-reactivity Complement Phagocytosis Macrophages

12 related topics

Function

Pathogen Innate immunity Drosophila Cytokines Leukocytes

11 related topics

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases: TLR2, CD282, TIL4, toll like receptor 2
Available structures: Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1FYW, 1FYX, 1O77, 2Z7X, 2Z80
Band: 4q31.3 · 3|3 E3
Bgee: monocyte · blood · granulocyte · right lung · upper lobe of left lung
BioGPS: More reference expression data
Chr.: Chromosome 4 (human) · Chromosome 3 (mouse)

Topics to explore

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Overview

Function

Pathogen
Innate immunity
Drosophila
Cytokines Cytokine
Leukocytes Leukocyte
Gram-positive bacteria
Yeast
NF-κB
CYP1A1
Polycyclic aromatic hydrocarbons Polycyclic aromatic hydrocarbon
Benzo(a)pyrene

Background

Antibodies Antibody
Cross-reactivity
Complement Complement system
Phagocytosis
Macrophages Macrophage
Dendritic cells Dendritic cell
Spleen
Lymph nodes Lymph node
Presents Antigen presentation
Antigen
Phylogenetically Phylogenetics
Lipids Lipid

Mechanism

Bacterial Bacteria
Fungal Fungus
Viral Virus
Endogenous Endogeny
Endosomes Endosome
Phagosomes Phagosome
PMNs Granulocyte
Tumor necrosis factor-alpha
Interleukins
IL-1α IL1A
IL-1β IL1B
IL-6 Interleukin 6
IL-8 Interleukin 8
IL-12 Interleukin 12
Modulins Modulins?action=edit&redlink=1
Th2 T helper cell
Immune deviation Immune deviation?action=edit&redlink=1
Conjugates Conjugate vaccine
Vaccines Vaccine
Expression Gene expression
TCR T cell receptor
Proliferation Cell growth
Inflammation
TNF-β Lymphotoxin
IL-10 Interleukin 10
Polymorphisms Polymorphism (biology)
Signal transduction

Interactions

Interact Protein-protein interaction
TOLLIP
PAMPs Pathogen-associated molecular pattern
Glycophosphatidylinositols Glycophosphatidylinositol
Plasmodium falciparum

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

Map overview Semantic statistics

Nodes94

Edges93

Triples143

Avg. degree1.98

Density0.021277

Components1

How this topic connects Entity context

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Toll-like receptor 2

Top relations

Gene ontology · 74

Toll-like receptor 2 → apoptotic process, cell body, cell projection, cell surface, cellular response to bacterial lipopeptide, cellular response to diacyl bacterial lipopeptide, cellular response to lipoteichoic acid, cellular response to triacyl bacterial lipopeptide, central nervous system myelin formation, cytoplasm, cytoplasmic vesicle, defense response to Gram-positive bacterium, detection of diacyl bacterial lipopeptide, detection of triacyl bacterial lipopeptide, Golgi apparatus, I-kappaB phosphorylation, immune response, immune system process, inflammatory response, innate immune response

Bgee · 19

Toll-like receptor 2 → blood, bone marrow, bone marrow cell, calvaria, cartilage tissue, cervix, conjunctival fornix, epithelium of lens, granulocyte, islet of Langerhans, monocyte, periodontal fiber, right lung, right lung lobe, spleen, stroma of bone marrow, tibiofemoral joint, upper lobe of left lung, vestibular membrane of cochlear duct

RNA expression pattern · 19

Band · 2

Toll-like receptor 2 → 3|3 E3, 4q31.3

Chr. · 2

Toll-like receptor 2 → Chromosome 3 (mouse), Chromosome 4 (human)

End · 2

Toll-like receptor 2 → 153,706,260 bp, 83,749,074 bp

Aliases · 1

Toll-like receptor 2 → TLR2, CD282, TIL4, toll like receptor 2

Available structures · 1

Toll-like receptor 2 → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1FYW, 1FYX, 1O77, 2Z7X, 2Z80

BioGPS · 1

Toll-like receptor 2 → More reference expression data

Databases · 1

Toll-like receptor 2 → NCBI: entry; OMA: entry

Important terminology Word statistics

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

tlr2 immune gene receptor cells expressed bp toll-like system human also chr band protein expression membrane antibodies chromosome innate activation

Entity relationships Subject–Predicate–Object triples

Subject	Predicate	Object	Confidence	Src
Toll-like receptor 2	Aliases	TLR2, CD282, TIL4, toll like receptor 2	1.00	infobox
Toll-like receptor 2	Available structures	Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1FYW, 1FYX, 1O77, 2Z7X, 2Z80	1.00	infobox
Toll-like receptor 2	Band	4q31.3	1.00	infobox
Toll-like receptor 2	Band	3\|3 E3	1.00	infobox
Toll-like receptor 2	Bgee	monocyte	1.00	infobox
Toll-like receptor 2	Bgee	blood	1.00	infobox
Toll-like receptor 2	Bgee	granulocyte	1.00	infobox
Toll-like receptor 2	Bgee	right lung	1.00	infobox
Toll-like receptor 2	Bgee	upper lobe of left lung	1.00	infobox
Toll-like receptor 2	Bgee	spleen	1.00	infobox
Toll-like receptor 2	Bgee	bone marrow	1.00	infobox
Toll-like receptor 2	Bgee	cartilage tissue	1.00	infobox
Toll-like receptor 2	Bgee	bone marrow cell	1.00	infobox
Toll-like receptor 2	Bgee	periodontal fiber	1.00	infobox
Toll-like receptor 2	Bgee	stroma of bone marrow	1.00	infobox
Toll-like receptor 2	Bgee	right lung lobe	1.00	infobox
Toll-like receptor 2	Bgee	tibiofemoral joint	1.00	infobox
Toll-like receptor 2	Bgee	calvaria	1.00	infobox
Toll-like receptor 2	Bgee	islet of Langerhans	1.00	infobox
Toll-like receptor 2	Bgee	conjunctival fornix	1.00	infobox
Toll-like receptor 2	Bgee	epithelium of lens	1.00	infobox
Toll-like receptor 2	Bgee	cervix	1.00	infobox
Toll-like receptor 2	Bgee	vestibular membrane of cochlear duct	1.00	infobox
Toll-like receptor 2	BioGPS	More reference expression data	1.00	infobox
Toll-like receptor 2	Chr.	Chromosome 4 (human)	1.00	infobox
Toll-like receptor 2	Chr.	Chromosome 3 (mouse)	1.00	infobox
Toll-like receptor 2	Databases	NCBI: entry; OMA: entry	1.00	infobox
Toll-like receptor 2	End	153,706,260 bp	1.00	infobox
Toll-like receptor 2	End	83,749,074 bp	1.00	infobox
Toll-like receptor 2	Ensembl	ENSG00000137462	1.00	infobox

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Connections between topic areas Semantic bridges

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Mechanism

Expression

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Overview

Function

Background

Mechanism

Expression

Cancer

Agonists

Interactions

Advanced semantic analysis

Map overview Semantic statistics

Toll-like receptor 2

How this topic connects Entity context

Toll-like receptor 2

Top relations

Important terminology Word statistics

Important terminology

Entity relationships Subject–Predicate–Object triples

Related concept clusters Concept neighborhoods

Connections between topic areas Semantic bridges