IRAK2

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Explore the main themes, entities and connections around IRAK2. Start with the topic map, then use the sections below for research and deeper semantic analysis.

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Interactions

Interact TRAF6 Myd88

3 related topics

Overview

Enzyme Gene

2 related topics

Key facts & relationships

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Aliases: IRAK2, IRAK-2, interleukin 1 receptor associated kinase 2
Available structures: Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes3MOP
Band: 3p25.3 · 6 E3|6 52.82 cM
Bgee: cartilage tissue · pancreatic epithelial cell · secondary oocyte · pancreatic ductal cell · palpebral conjunctiva
BioGPS: More reference expression data
Chr.: Chromosome 3 (human) · Chromosome 6 (mouse)

Topics to explore

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Overview

Interactions

Interact Protein-protein interaction
TRAF6
Myd88

Advanced semantic analysis

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Map overview Semantic statistics

Nodes8

Edges7

Triples98

Avg. degree1.75

Density0.25

Components1

How this topic connects Entity context

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IRAK2

Top relations

Gene ontology · 30

IRAK2 → ATP binding, cytokine-mediated signaling pathway, cytoplasm, cytosol, endosome membrane, I-kappaB kinase/NF-kappaB signaling, inflammatory response, interleukin-1-mediated signaling pathway, intracellular signal transduction, JNK cascade, lipopolysaccharide-mediated signaling pathway, MyD88-dependent toll-like receptor signaling pathway, negative regulation of DNA-binding transcription factor activity, negative regulation of NF-kappaB transcription factor activity, nucleotide binding, nucleotide-binding oligomerization domain containing signaling pathway, nucleus, plasma membrane, positive regulation of NF-kappaB transcription factor activity, protein binding

Bgee · 20

IRAK2 → amniotic fluid, cartilage tissue, colon, duodenum, endothelial cell, gastrocnemius muscle, granulocyte, ileum, islet of Langerhans, jejunum, left lung, palpebral conjunctiva, pancreatic ductal cell, pancreatic epithelial cell, proximal tubule, secondary oocyte, spleen, tibialis anterior muscle, urinary bladder, white adipose tissue

RNA expression pattern · 20

related to Function · 3

IRAK2 → IL1-induced, IL1R, NF-kappaB

Band · 2

IRAK2 → 3p25.3, 6 E3|6 52.82 cM

Chr. · 2

IRAK2 → Chromosome 3 (human), Chromosome 6 (mouse)

End · 2

IRAK2 → 10,243,745 bp, 113,671,987 bp

related to Interactions · 2

IRAK2 → Myd88, TRAF6

Aliases · 1

IRAK2 → IRAK2, IRAK-2, interleukin 1 receptor associated kinase 2

Available structures · 1

IRAK2 → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes3MOP

Important terminology Word statistics

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Important terminology

bp chr human band gene chromosome interleukin-1 location receptor kinase mouse function receptor-associated search 243 745 end 10 e3 52

Entity relationships Subject–Predicate–Object triples

Subject	Predicate	Object	Confidence	Src
IRAK2	Aliases	IRAK2, IRAK-2, interleukin 1 receptor associated kinase 2	1.00	infobox
IRAK2	Available structures	Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes3MOP	1.00	infobox
IRAK2	Band	3p25.3	1.00	infobox
IRAK2	Band	6 E3\|6 52.82 cM	1.00	infobox
IRAK2	Bgee	cartilage tissue	1.00	infobox
IRAK2	Bgee	pancreatic epithelial cell	1.00	infobox
IRAK2	Bgee	secondary oocyte	1.00	infobox
IRAK2	Bgee	pancreatic ductal cell	1.00	infobox
IRAK2	Bgee	palpebral conjunctiva	1.00	infobox
IRAK2	Bgee	gastrocnemius muscle	1.00	infobox
IRAK2	Bgee	tibialis anterior muscle	1.00	infobox
IRAK2	Bgee	amniotic fluid	1.00	infobox
IRAK2	Bgee	endothelial cell	1.00	infobox
IRAK2	Bgee	islet of Langerhans	1.00	infobox
IRAK2	Bgee	granulocyte	1.00	infobox
IRAK2	Bgee	jejunum	1.00	infobox
IRAK2	Bgee	urinary bladder	1.00	infobox
IRAK2	Bgee	white adipose tissue	1.00	infobox
IRAK2	Bgee	spleen	1.00	infobox
IRAK2	Bgee	left lung	1.00	infobox
IRAK2	Bgee	colon	1.00	infobox
IRAK2	Bgee	proximal tubule	1.00	infobox
IRAK2	Bgee	duodenum	1.00	infobox
IRAK2	Bgee	ileum	1.00	infobox
IRAK2	BioGPS	More reference expression data	1.00	infobox
IRAK2	Chr.	Chromosome 3 (human)	1.00	infobox
IRAK2	Chr.	Chromosome 6 (mouse)	1.00	infobox
IRAK2	Databases	NCBI: entry; OMA: entry	1.00	infobox
IRAK2	End	10,243,745 bp	1.00	infobox
IRAK2	End	113,671,987 bp	1.00	infobox

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