TICAM1

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Structure

TLR4 TRAF TRAF6 TLR3

4 related topics

Areas of research

Pathogenesis Septic shock Tumor Rheumatoid arthritis

4 related topics

Overview

Adapter Toll-like receptors MyD88 Cytokines Chemokines

5 related topics

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases: TICAM1, IIAE6, MyD88-3, PRVTIRB, TICAM-1, TRIF, toll like receptor adaptor molecule 1, TIR domain containing adaptor molecule 1
Available structures: Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2M1X, 2M63, 3RC4, 4BSX, 4C0M, 5JEL
Band: 19p13.3 · 17|17 D
Bgee: buccal mucosa cell · granulocyte · mucosa of transverse colon · parotid gland · gastrocnemius muscle
BioGPS: n/a
Chr.: Chromosome 19 (human) · Chromosome 17 (mouse)

Topics to explore

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Overview

Adapter Signal transducing adaptor protein
Toll-like receptors
MyD88
Cytokines
Chemokines

Structure

Areas of research

Advanced semantic analysis

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Map overview Semantic statistics

Nodes17

Edges16

Triples128

Avg. degree1.88

Density0.117647

Components1

How this topic connects Entity context

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TICAM1

Top relations

Gene ontology · 38

TICAM1 → apoptotic process, apoptotic signaling pathway, autophagosome, cellular response to lipopolysaccharide, cytoplasmic vesicle, cytosol, defense response to virus, endosome membrane, I-kappaB kinase/NF-kappaB signaling, immune system process, inflammatory response, innate immune response, lipopolysaccharide-mediated signaling pathway, macrophage activation involved in immune response, MyD88-independent toll-like receptor signaling pathway, necroptosis, negative regulation of MyD88-independent toll-like receptor signaling pathway, positive regulation of autophagy, positive regulation of B cell activation, positive regulation of B cell proliferation

Bgee · 19

TICAM1 → ascending aorta, body of stomach, buccal mucosa cell, colon, duodenum, epithelium of stomach, female urethra, gastrocnemius muscle, granulocyte, ileum, jejunum, lacrimal gland, mucosa of transverse colon, muscle of thigh, parotid gland, right lobe of liver, skin of abdomen, urethra, yolk sac

RNA expression pattern · 19

related to Structure · 15

TICAM1 → Cells, Curiously, Destruction, IRAK, MyD88, NF-κB, RIP, RIP1, RIP3, This, Three TRAF-binding, TLR3, TLR4, TLRs, TRAF6

related to Areas of research · 7

TICAM1 → Better, Experiments, Investigations, It, The, TICAM1-deficient, TLR

related to External links · 7

TICAM1 → KEGG, KO, Medicine Medical Subject Headings, MeSH, National Library, Reference, Toll-like

Band · 2

TICAM1 → 17|17 D, 19p13.3

Chr. · 2

TICAM1 → Chromosome 17 (mouse), Chromosome 19 (human)

End · 2

TICAM1 → 4,831,712 bp, 56,583,786 bp

Aliases · 1

TICAM1 → TICAM1, IIAE6, MyD88-3, PRVTIRB, TICAM-1, TRIF, toll like receptor adaptor molecule 1, TIR domain containing adaptor molecule 1

Important terminology Word statistics

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Important terminology

signaling bp human domain immune chr band tlrs toll-like response chromosome 19 receptors cascade activation gene tir downstream adapter protein

Entity relationships Subject–Predicate–Object triples

Subject	Predicate	Object	Confidence	Src
TICAM1	Aliases	TICAM1, IIAE6, MyD88-3, PRVTIRB, TICAM-1, TRIF, toll like receptor adaptor molecule 1, TIR domain containing adaptor molecule 1	1.00	infobox
TICAM1	Available structures	Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2M1X, 2M63, 3RC4, 4BSX, 4C0M, 5JEL	1.00	infobox
TICAM1	Band	19p13.3	1.00	infobox
TICAM1	Band	17\|17 D	1.00	infobox
TICAM1	Bgee	buccal mucosa cell	1.00	infobox
TICAM1	Bgee	granulocyte	1.00	infobox
TICAM1	Bgee	mucosa of transverse colon	1.00	infobox
TICAM1	Bgee	parotid gland	1.00	infobox
TICAM1	Bgee	gastrocnemius muscle	1.00	infobox
TICAM1	Bgee	ascending aorta	1.00	infobox
TICAM1	Bgee	skin of abdomen	1.00	infobox
TICAM1	Bgee	muscle of thigh	1.00	infobox
TICAM1	Bgee	body of stomach	1.00	infobox
TICAM1	Bgee	right lobe of liver	1.00	infobox
TICAM1	Bgee	jejunum	1.00	infobox
TICAM1	Bgee	ileum	1.00	infobox
TICAM1	Bgee	duodenum	1.00	infobox
TICAM1	Bgee	lacrimal gland	1.00	infobox
TICAM1	Bgee	epithelium of stomach	1.00	infobox
TICAM1	Bgee	urethra	1.00	infobox
TICAM1	Bgee	female urethra	1.00	infobox
TICAM1	Bgee	yolk sac	1.00	infobox
TICAM1	Bgee	colon	1.00	infobox
TICAM1	BioGPS	n/a	1.00	infobox
TICAM1	Chr.	Chromosome 19 (human)	1.00	infobox
TICAM1	Chr.	Chromosome 17 (mouse)	1.00	infobox
TICAM1	Databases	NCBI: entry; OMA: entry	1.00	infobox
TICAM1	End	4,831,712 bp	1.00	infobox
TICAM1	End	56,583,786 bp	1.00	infobox
TICAM1	Ensembl	ENSG00000127666	1.00	infobox

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