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A Muse cell (Multi-lineage differentiating stress-enduring cell) is an endogenous non-cancerous pluripotent stem cell. They reside in the connective tissue of nearly every organ including the umbilical cord, bone marrow and peripheral blood, and are collectable from commercially obtainable mesenchymal cells such as human fibroblasts, bone…
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cells muse human cell stem bone tissue differentiate model ssea-3 marrow mesenchymal differentiation positive pluripotent clinical stroke without skin pluripotency
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| human fibroblasts | instance of | and are collectable from commercially obtainable mesenchymal cells | 0.80 | text |
| bone marrow-mesenchymal stem cells | instance of | and are collectable from commercially obtainable mesenchymal cells | 0.80 | text |
| adipose-derived stem cells as 1 | instance of | and are collectable from commercially obtainable mesenchymal cells | 0.80 | text |
| gene introduction.Intravenous injection of donor-Muse cells can be directly used for treatment without HLA-matching test or immunosuppressant treatment due to the specific immune privilege | instance of | of mesenchymal stem cell transplantation.Have immunosuppressive and immunomodulatory effect.Pluripotent stem cells can be directly obtained from normal human tissues without usi… | 0.80 | text |
| fibroblasts | instance of | Hela cells and human fibroblast-derived iPS cells showed high telomerase activity while Muse was at nearly the same level as that in somatic cells | 0.80 | text |
| alkaline phosphatase reactivities | instance of | Muse cell clusters are positive for pluripotency indicators | 0.80 | text |
| Nanog | instance of | Muse cell clusters are positive for pluripotency indicators | 0.80 | text |
| Oct3/4 | instance of | Muse cell clusters are positive for pluripotency indicators | 0.80 | text |
| Sox2 | instance of | Muse cell clusters are positive for pluripotency indicators | 0.80 | text |
| PAR4 | instance of | Muse cell clusters are positive for pluripotency indicators | 0.80 | text |
| blood vessels or dermal papilla.Adipose tissue | instance of | Their location is not related to particular structures | 0.80 | text |
| human CYP1A2 | instance of | and express mature functional markers | 0.80 | text |
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