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Immune privilege

Certain sites of the mammalian body have immune privilege (no immune response), meaning they are able to tolerate the introduction of antigens without eliciting an inflammatory immune response. Tissue grafts are normally recognised as foreign antigens by the body and attacked by the immune system.

History, Applications & Research

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Overview

Mechanisms

Immunologically privileged sites

Clinical applications

History of research

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Map overview Semantic statistics

Immune privilege

Nodes70
Edges69
Triples34
Avg. degree1.97
Density0.028571
Components1

How this topic connects Entity context

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Immune privilege

Top relations

has application · 10
Immune privilege → ACAID, Another, Compared, Even, Immune, Research, Sertoli, The Sertoli, There, Treg
related to Placenta and fetus · 10
Immune privilege → CD25, CD4, Experiments, In, Increased, Regulatory, The, This, Treg, Tregs
related to Central nervous system · 5
Immune privilege → CNS, Current, In, It, The
related to Mechanisms · 4
Immune privilege → Antigens, Immune, Other, Physical
related to history · 3
Immune privilege → More, Peter Medawar, The

Important terminology Word statistics

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Important terminology

immune cells system eye antigens privilege privileged cns response sites tissue antigen thought sertoli fetus lymph nodes body central inflammatory

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
TGF-βPresence of neuropeptidesConstitutive expression of Fas ligand that controls the entry of Fas-expressing lymphoid cells.The nature of isolation of immunologically privileged sites from the rest of the body's immune system can cause them to become targets of autoimmune diseases or conditionsinstance oflow polymorphic class Ib MHC moleculesIncreased expression of surface molecules that inhibit complement activationLocal production of immunosuppressive cytokines0.80text
including sympathetic ophthalmia in the eyeinstance oflow polymorphic class Ib MHC moleculesIncreased expression of surface molecules that inhibit complement activationLocal production of immunosuppressive cytokines0.80text
Immune privilegehas applicationThere0.60section
Immune privilegehas applicationCompared0.60section
Immune privilegehas applicationImmune0.60section
Immune privilegehas applicationResearch0.60section
Immune privilegehas applicationACAID0.60section
Immune privilegehas applicationTreg0.60section
Immune privilegehas applicationAnother0.60section
Immune privilegehas applicationSertoli0.60section
Immune privilegehas applicationThe Sertoli0.60section
Immune privilegehas applicationEven0.60section

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