T-box transcription factor T

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Explore the main themes, entities and connections around T-box transcription factor T. Start with the topic map, then use the sections below for research and deeper semantic analysis.

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Role in disease

Chordoma Germ cell tumors Hemangioblastoma GIST Lung cancer

24 related topics

Overview

Gene Transcription factor T-box family Homologs Non-bilaterians

23 related topics

Role in development

Blastopore Mesoderm Cellular differentiation Dysplasia Inner cell mass

10 related topics

History

Nadezhda Alexandrovna Dobrovolskaya-Zavadskaya Mesoderm Notochord HGNC

4 related topics

Key facts & relationships

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Aliases: TBXT, T, brachyury homolog (mouse), SAVA, TFT, T brachyury transcription factor, T-box transcription factor T, T
Band: 6q27 · 17 A1|17 4.92 cM
Bgee: gonad · testicle · oocyte · pars reticulata · renal medulla
BioGPS: n/a
Chr.: Chromosome 6 (human) · Chromosome 17 (mouse)
Databases: NCBI: entry; OMA: entry

Topics to explore

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Overview

Gene
Transcription factor
T-box family T-box
Homologs Sequence homology
Non-bilaterians Bilateria
Cnidaria
Placozoa
Porifera Sponge
Ctenophora
Alu element
Transposons Transposable element
Nucleotides Nucleotide
Stem-loop
Alternative splicing event Alternative splicing
Transcription Transcription (biology)
Exon
Nucleotide excision repair
RNA polymerase
Isoform Protein isoform
Protein kinase
Hominoidea Ape
Speciation
Homo sapiens Human

History

Nadezhda Alexandrovna Dobrovolskaya-Zavadskaya Nadiya Dobrovolska-Zavadska
Mesoderm
Notochord
HGNC HUGO Gene Nomenclature Committee

Role in development

Role in hominid evolution

Vertebrate
Genotype
Lumbar Lumbar vertebrae
Sacral Sacrum
Tail vertebrae Vertebral column
Phenotype
Mutation
Hominidae
Taxa Taxon

Role in disease

Chordoma
Germ cell tumors Germ cell tumor
Hemangioblastoma
GIST Gastrointestinal stromal tumor
Lung cancer
Small cell carcinoma Small-cell carcinoma
Breast cancer
Colon cancer Colorectal cancer
Hepatocellular carcinoma
Prostate cancer
Superenhancer Super-enhancer
Epithelial–mesenchymal transition
E-cadherin
AKT
Metastasis
Embryonic Embryo
Genetic instability Genome instability
Neural tube
Spina bifida
Sacral agenesis
Spinal cord
Neurogenic bladder dysfunction
Hydrocephalus
Fibrosis

Advanced semantic analysis

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Map overview Semantic statistics

Nodes76

Edges75

Triples102

Avg. degree1.97

Density0.026316

Components1

How this topic connects Entity context

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T-box transcription factor T

Top relations

Gene ontology · 42

T-box transcription factor T → anatomical structure morphogenesis, anterior/posterior axis specification, embryo, anterior/posterior pattern specification, BMP signaling pathway, bone morphogenesis, canonical Wnt signaling pathway, cellular response to retinoic acid, chromatin, cytoplasm, determination of heart left/right asymmetry, DNA binding, DNA-binding transcription factor activity, DNA-binding transcription factor activity, RNA polymerase II-specific, embryonic skeletal system development, heart morphogenesis, mesoderm development, mesoderm migration involved in gastrulation, multicellular organism development, negative regulation of DNA-binding transcription factor activity, negative regulation of transcription by RNA polymerase II

Bgee · 19

T-box transcription factor T → embryo, embryonic organizer, epiblast, external globus pallidus, female urethra, gonad, human penis, mesoderm, notochord, oocyte, paraxial mesoderm, pars reticulata, primitive streak, renal medulla, secondary oocyte, synovial joint, synovial membrane, tail of embryo, testicle

RNA expression pattern · 19

Band · 2

T-box transcription factor T → 17 A1|17 4.92 cM, 6q27

Chr. · 2

T-box transcription factor T → Chromosome 17 (mouse), Chromosome 6 (human)

End · 2

T-box transcription factor T → 166,168,700 bp, 8,661,328 bp

Aliases · 1

T-box transcription factor T → TBXT, T, brachyury homolog (mouse), SAVA, TFT, T brachyury transcription factor, T-box transcription factor T, T

BioGPS · 1

T-box transcription factor T → n/a

Databases · 1

T-box transcription factor T → NCBI: entry; OMA: entry

Ensembl · 1

T-box transcription factor T → ENSG00000164458

Important terminology Word statistics

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Important terminology

brachyury transcription tbxt gene tail factor also chordoma mutation human cancer protein development expression associated cells bp t-box expressed due

Entity relationships Subject–Predicate–Object triples

Subject	Predicate	Object	Confidence	Src
T-box transcription factor T	Aliases	TBXT, T, brachyury homolog (mouse), SAVA, TFT, T brachyury transcription factor, T-box transcription factor T, T	1.00	infobox
T-box transcription factor T	Band	6q27	1.00	infobox
T-box transcription factor T	Band	17 A1\|17 4.92 cM	1.00	infobox
T-box transcription factor T	Bgee	gonad	1.00	infobox
T-box transcription factor T	Bgee	testicle	1.00	infobox
T-box transcription factor T	Bgee	oocyte	1.00	infobox
T-box transcription factor T	Bgee	pars reticulata	1.00	infobox
T-box transcription factor T	Bgee	renal medulla	1.00	infobox
T-box transcription factor T	Bgee	synovial joint	1.00	infobox
T-box transcription factor T	Bgee	secondary oocyte	1.00	infobox
T-box transcription factor T	Bgee	human penis	1.00	infobox
T-box transcription factor T	Bgee	external globus pallidus	1.00	infobox
T-box transcription factor T	Bgee	synovial membrane	1.00	infobox
T-box transcription factor T	Bgee	tail of embryo	1.00	infobox
T-box transcription factor T	Bgee	paraxial mesoderm	1.00	infobox
T-box transcription factor T	Bgee	primitive streak	1.00	infobox
T-box transcription factor T	Bgee	notochord	1.00	infobox
T-box transcription factor T	Bgee	mesoderm	1.00	infobox
T-box transcription factor T	Bgee	embryonic organizer	1.00	infobox
T-box transcription factor T	Bgee	epiblast	1.00	infobox
T-box transcription factor T	Bgee	embryo	1.00	infobox
T-box transcription factor T	Bgee	female urethra	1.00	infobox
T-box transcription factor T	BioGPS	n/a	1.00	infobox
T-box transcription factor T	Chr.	Chromosome 6 (human)	1.00	infobox
T-box transcription factor T	Chr.	Chromosome 17 (mouse)	1.00	infobox
T-box transcription factor T	Databases	NCBI: entry; OMA: entry	1.00	infobox
T-box transcription factor T	End	166,168,700 bp	1.00	infobox
T-box transcription factor T	End	8,661,328 bp	1.00	infobox
T-box transcription factor T	Ensembl	ENSG00000164458	1.00	infobox
T-box transcription factor T	Entrez	6862	1.00	infobox

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