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Mediator of DNA damage checkpoint protein 1 is a 2080 amino acid long protein that in humans is encoded by the MDC1 gene located on the short arm (p) of chromosome 6. MDC1 protein is a regulator of the Intra-S phase and the G2/M cell cycle checkpoints and recruits repair proteins to the site of DNA damage. It is involved in determining cell survival fate…
Function, Interactions & Regulation
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protein dna damage domain cell p53 human chromosome atm cells bp ddr gene chr band mediator cycle response amino checkpoints
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| MDC1 | Aliases | MDC1, NFBD1, mediator of DNA damage checkpoint 1 | 1.00 | infobox |
| MDC1 | Available structures | Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2ADO, 2AZM, 2ETX, 3K05, 3UEO, 3UMZ, 3UN0, 3UNM, 3UNN, 3UOT | 1.00 | infobox |
| MDC1 | Band | 6p21.33 | 1.00 | infobox |
| MDC1 | Band | 17|17 B1 | 1.00 | infobox |
| MDC1 | Bgee | right testis | 1.00 | infobox |
| MDC1 | Bgee | left testis | 1.00 | infobox |
| MDC1 | Bgee | right lobe of thyroid gland | 1.00 | infobox |
| MDC1 | Bgee | ventricular zone | 1.00 | infobox |
| MDC1 | Bgee | left lobe of thyroid gland | 1.00 | infobox |
| MDC1 | Bgee | right ovary | 1.00 | infobox |
| MDC1 | Bgee | left ovary | 1.00 | infobox |
| MDC1 | Bgee | gastric mucosa | 1.00 | infobox |
| MDC1 | Bgee | body of uterus | 1.00 | infobox |
| MDC1 | Bgee | pituitary gland | 1.00 | infobox |
| MDC1 | Bgee | tail of embryo | 1.00 | infobox |
| MDC1 | Bgee | spermatocyte | 1.00 | infobox |
| MDC1 | Bgee | genital tubercle | 1.00 | infobox |
| MDC1 | Bgee | zygote | 1.00 | infobox |
| MDC1 | Bgee | cumulus cell | 1.00 | infobox |
| MDC1 | Bgee | spermatid | 1.00 | infobox |
| MDC1 | Bgee | hand | 1.00 | infobox |
| MDC1 | Bgee | yolk sac | 1.00 | infobox |
| MDC1 | Bgee | neural layer of retina | 1.00 | infobox |
| MDC1 | BioGPS | More reference expression data | 1.00 | infobox |
| MDC1 | Chr. | Chromosome 6 (human) | 1.00 | infobox |
| MDC1 | Chr. | Chromosome 17 (mouse) | 1.00 | infobox |
| MDC1 | Databases | NCBI: entry; OMA: entry | 1.00 | infobox |
| MDC1 | End | 30,717,447 bp | 1.00 | infobox |
| MDC1 | End | 36,170,562 bp | 1.00 | infobox |
| MDC1 | Ensembl | ENSG00000224587 ENSG00000237095 ENSG00000137337 ENSG00000206481 ENSG00000234012 ENSG00000231135 ENSG00000228575 ENSG00000225589 | 1.00 | infobox |
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