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C-C chemokine receptor type 7

C-C chemokine receptor type 7 is a protein that in humans is encoded by the CCR7 gene. Two ligands have been identified for this receptor: the chemokine (C-C motif) ligand 19 (CCL19/ELC) and (C-C motif) ligand 21 (CCL21).: Figure 2 The ligands have similar affinity for the receptor, though CCL19 has been shown to induce internalisation of CCR7 and…

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Aliases
CCR7, BLR2, CC-CKR-7, CCR-7, CD197, CDw197, CMKBR7, EBI1, C-C motif chemokine receptor 7
Band
17q21.2 · 11|11 D
Bgee
appendix · lymph node · blood · granulocyte · thymus
BioGPS
More reference expression data
Chr.
Chromosome 17 (human) · Chromosome 11 (mouse)
Databases
NCBI: entry; OMA: entry

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C-C chemokine receptor type 7

Nodes41
Edges40
Triples122
Avg. degree1.95
Density0.04878
Components1

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C-C chemokine receptor type 7

Top relations

Gene ontology · 67
C-C chemokine receptor type 7 → activation of GTPase activity, C-C chemokine binding, C-C chemokine receptor activity, C-C motif chemokine 19 receptor activity, C-C motif chemokine 21 receptor activity, calcium-mediated signaling, cell chemotaxis, cell surface, cellular response to cytokine stimulus, chemokine (C-C motif) ligand 19 binding, chemokine (C-C motif) ligand 19 signaling pathway, chemokine (C-C motif) ligand 21 binding, chemokine (C-C motif) ligand 21 signaling pathway, chemokine binding, chemokine receptor activity, chemokine-mediated signaling pathway, chemotaxis, dendritic cell chemotaxis, establishment of T cell polarity, external side of plasma membrane
Bgee · 14
C-C chemokine receptor type 7 → appendix, blood, bone marrow, embryo, granulocyte, lymph node, mesenteric lymph nodes, mucosa of ileum, right lung lobe, spleen, subcutaneous adipose tissue, superficial temporal artery, testicle, thymus
RNA expression pattern · 14
C-C chemokine receptor type 7 → appendix, blood, bone marrow, embryo, granulocyte, lymph node, mesenteric lymph nodes, mucosa of ileum, right lung lobe, spleen, subcutaneous adipose tissue, superficial temporal artery, testicle, thymus
Band · 2
C-C chemokine receptor type 7 → 11|11 D, 17q21.2
Chr. · 2
C-C chemokine receptor type 7 → Chromosome 11 (mouse), Chromosome 17 (human)
End · 2
C-C chemokine receptor type 7 → 40,565,472 bp, 99,045,903 bp
Aliases · 1
C-C chemokine receptor type 7 → CCR7, BLR2, CC-CKR-7, CCR-7, CD197, CDw197, CMKBR7, EBI1, C-C motif chemokine receptor 7
BioGPS · 1
C-C chemokine receptor type 7 → More reference expression data
Databases · 1
C-C chemokine receptor type 7 → NCBI: entry; OMA: entry
Ensembl · 1
C-C chemokine receptor type 7 → ENSG00000126353

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Important terminology

ccr7 receptor cells cell human dendritic gene also thymus bp expression lymph nodes chr band ccl19 ccl21 protein c-c chemokine

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
C-C chemokine receptor type 7AliasesCCR7, BLR2, CC-CKR-7, CCR-7, CD197, CDw197, CMKBR7, EBI1, C-C motif chemokine receptor 71.00infobox
C-C chemokine receptor type 7Band17q21.21.00infobox
C-C chemokine receptor type 7Band11|11 D1.00infobox
C-C chemokine receptor type 7Bgeeappendix1.00infobox
C-C chemokine receptor type 7Bgeelymph node1.00infobox
C-C chemokine receptor type 7Bgeeblood1.00infobox
C-C chemokine receptor type 7Bgeegranulocyte1.00infobox
C-C chemokine receptor type 7Bgeethymus1.00infobox
C-C chemokine receptor type 7Bgeespleen1.00infobox
C-C chemokine receptor type 7Bgeesuperficial temporal artery1.00infobox
C-C chemokine receptor type 7Bgeemucosa of ileum1.00infobox
C-C chemokine receptor type 7Bgeetesticle1.00infobox
C-C chemokine receptor type 7Bgeebone marrow1.00infobox
C-C chemokine receptor type 7Bgeemesenteric lymph nodes1.00infobox
C-C chemokine receptor type 7Bgeeembryo1.00infobox
C-C chemokine receptor type 7Bgeesubcutaneous adipose tissue1.00infobox
C-C chemokine receptor type 7Bgeeright lung lobe1.00infobox
C-C chemokine receptor type 7BioGPSMore reference expression data1.00infobox
C-C chemokine receptor type 7Chr.Chromosome 17 (human)1.00infobox
C-C chemokine receptor type 7Chr.Chromosome 11 (mouse)1.00infobox
C-C chemokine receptor type 7DatabasesNCBI: entry; OMA: entry1.00infobox
C-C chemokine receptor type 7End40,565,472 bp1.00infobox
C-C chemokine receptor type 7End99,045,903 bp1.00infobox
C-C chemokine receptor type 7EnsemblENSG000001263531.00infobox
C-C chemokine receptor type 7Entrez12361.00infobox
C-C chemokine receptor type 7External IDsOMIM: 600242; MGI: 103011; GeneCards: CCR71.00infobox
C-C chemokine receptor type 7Gene location (Human)Gene location (Human)Chr.Chromosome 17 (human)Band17q21.2Start40,553,769 bpEnd40,565,472 bp1.00infobox
C-C chemokine receptor type 7Gene location (Mouse)Gene location (Mouse)Chr.Chromosome 11 (mouse)Band11|11 DStart99,035,022 bpEnd99,045,903 bp1.00infobox
C-C chemokine receptor type 7Gene ontologyC-C motif chemokine 19 receptor activity1.00infobox
C-C chemokine receptor type 7Gene ontologyC-C motif chemokine 21 receptor activity1.00infobox

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