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Intermediate filament

Intermediate filaments (IFs) are cytoskeletal structural components found in the cells of vertebrates, and many invertebrates. Homologues of the IF protein have been noted in an invertebrate, the cephalochordate Branchiostoma.

Structure, Types & Function

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Key facts & relationships

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AlphaFold
IPR001322 · PF00932
Available protein structures:
IPR001322 · PF00932
InterPro
IPR001322
PDB
IPR001322 PF00932 (ECOD; PDBsum)
Pfam
PF00932
PROSITE
PDOC00198

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Overview

Structure

Biomechanical properties

Types

Function

Diseases arising from mutations in IF genes

In other organisms

Advanced semantic analysis

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Map overview Semantic statistics

Intermediate filament

Nodes103
Edges102
Triples48
Avg. degree1.98
Density0.019417
Components1

How this topic connects Entity context

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Intermediate filament

Top relations

related to In other organisms · 12
Intermediate filament → Bilateria, Cytoplasmic IFs, Functionally-similar, IF, IF-like, In, IV, The Hydra, There, They, VI, With
related to Type III · 11
Intermediate filament → Desmin IFs, GFAP, Glial, IF, III, III IF, Peripherin, Syncoilin, There, They, Vimentin
related to Structure · 6
Intermediate filament → Analysis, As, IF, Structural, The, This
related to Types · 5
Intermediate filament → Animal IFs, However, IFs, In, There
related to Type IV · 3
Intermediate filament → Alpha-internexinNeurofilaments, IV, SyneminSyncoilin
AlphaFold · 2
Intermediate filament → IPR001322, PF00932
Available protein structures: · 2
Intermediate filament → IPR001322, PF00932
InterPro · 1
Intermediate filament → IPR001322
PDB · 1
Intermediate filament → IPR001322 PF00932 (ECOD; PDBsum)
Pfam · 1
Intermediate filament → PF00932

Important terminology Word statistics

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Important terminology

proteins protein intermediate filaments type lamins nuclear cells structure lamin ifs types filament citation needed found sequence keratin keratins microtubules

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Intermediate filamentAlphaFoldIPR0013221.00infobox
Intermediate filamentAlphaFoldPF009321.00infobox
Intermediate filamentAvailable protein structures:IPR0013221.00infobox
Intermediate filamentAvailable protein structures:PF009321.00infobox
Intermediate filamentInterProIPR0013221.00infobox
Intermediate filamentPDBIPR001322 PF00932 (ECOD; PDBsum)1.00infobox
Intermediate filamentPfamPF009321.00infobox
Intermediate filamentPROSITEPDOC001981.00infobox
Intermediate filamentSCOP21ivt / SCOPe / SUPFAM1.00infobox
Intermediate filamentSymbolIF_tail1.00infobox
Intermediate filamentis apair of two intertwined proteins that is called a coiled-coil structure0.90text
Intermediate filamentrelated to In other organismsIF0.60section

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    Min side: 3
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