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Synemin: History, Function & Cancer

Synemin, also known as desmuslin, is a protein that in humans is encoded by the SYNM gene. Synemin is an intermediate filament (IF) family member. IF proteins are cytoskeletal proteins that confer resistance to mechanical stress and are encoded by a dispersed multigene family. This protein has been found to form a linkage between desmin, which is a…

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Synemin topic overview

The analysis highlights History, Function and Cancer as prominent areas in the source structure around Synemin.

Related topics
24
Source areas
6
Connected nodes
30
Extracted relationships
102
Concept neighborhoods
10
Bridge connections
30

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

History · 6 topics
Overview · 6 topics
Function · 5 topics
Cancer · 3 topics
Properties · 2 topics
Splice variants · 2 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases
SYNM, DMN, SYN, synemin
Band
15q26.3 · 7|7 C
Bgee
seminal vesicula · saphenous vein · Skeletal muscle tissue of rectus abdominis · glutes · vastus lateralis muscle
BioGPS
n/a
Chr.
Chromosome 15 (human) · Chromosome 7 (mouse)
Databases
NCBI: entry; OMA: entry

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Function

Properties

Splice variants

Cancer

History

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How Synemin connects Entity context

The extracted context around Synemin shows recurring relationship patterns in the source. For example, Synemin → ankle, deltoid muscle, digastric muscle, glutes, knee joint, medial head of gastrocnemius muscle, muscle of thigh, optic nerve, right ventricle, saphenous vein, seminal vesicula, Skeletal muscle tissue of biceps brachii, Skeletal muscle tissue of rectus abdominis, sternocleidomastoid muscle, tail of epididymis, temporal muscle, tibialis anterior muscle, triceps brachii muscle, vastus lateralis muscle Another extracted example is Synemin → adherens junction, cell junction, costamere, cytoplasm, cytoskeleton, fast-twitch skeletal muscle fiber contraction, intermediate filament, intermediate filament binding, intermediate filament cytoskeleton organization, membrane, neurofilament cytoskeleton, protein binding, sarcolemma, structural constituent of cytoskeleton, structural constituent of muscle, structural molecule activity, vinculin binding. Use these groups to spot repeated connection types before inspecting the individual relationships.

Synemin

Top relations

Bgee · 19
Synemin → ankle, deltoid muscle, digastric muscle, glutes, knee joint, medial head of gastrocnemius muscle, muscle of thigh, optic nerve, right ventricle, saphenous vein, seminal vesicula, Skeletal muscle tissue of biceps brachii, Skeletal muscle tissue of rectus abdominis, sternocleidomastoid muscle, tail of epididymis, temporal muscle, tibialis anterior muscle, triceps brachii muscle, vastus lateralis muscle
RNA expression pattern · 19
Synemin → ankle, deltoid muscle, digastric muscle, glutes, knee joint, medial head of gastrocnemius muscle, muscle of thigh, optic nerve, right ventricle, saphenous vein, seminal vesicula, Skeletal muscle tissue of biceps brachii, Skeletal muscle tissue of rectus abdominis, sternocleidomastoid muscle, tail of epididymis, temporal muscle, tibialis anterior muscle, triceps brachii muscle, vastus lateralis muscle
Gene ontology · 17
Synemin → adherens junction, cell junction, costamere, cytoplasm, cytoskeleton, fast-twitch skeletal muscle fiber contraction, intermediate filament, intermediate filament binding, intermediate filament cytoskeleton organization, membrane, neurofilament cytoskeleton, protein binding, sarcolemma, structural constituent of cytoskeleton, structural constituent of muscle, structural molecule activity, vinculin binding
related to history · 9
Synemin → Although, IF, IF-associated, In, Mizuno, Sequence, Subsequent, The, Titeux
related to External links · 6
Synemin → Medicine, Medicine Medical Subject Headings, MeSH, National Library, This, United States National Library
related to Function · 5
Synemin → IF, IFs, It, While, Z-disk
related to Splice variants · 5
Synemin → An, Both, C-terminal, N-terminal, Three
Band · 2
Synemin → 15q26.3, 7|7 C
Chr. · 2
Synemin → Chromosome 15 (human), Chromosome 7 (mouse)
End · 2
Synemin → 67,409,490 bp, 99,135,593 bp

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

human protein bp desmuslin gene synm chr band desmin chromosome 15 intermediate filament muscle mechanical structural location chicken proteins encoded

Synemin relationships Subject–Predicate–Object triples

TTTA extracted 102 structured relationships around Synemin. Examples in this analysis include Synemin → Aliases → SYNM, DMN, SYN, synemin and Synemin → Band → 15q26.3. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
SyneminAliasesSYNM, DMN, SYN, synemin1.00infobox
SyneminBand15q26.31.00infobox
SyneminBand7|7 C1.00infobox
SyneminBgeeseminal vesicula1.00infobox
SyneminBgeesaphenous vein1.00infobox
SyneminBgeeSkeletal muscle tissue of rectus abdominis1.00infobox
SyneminBgeeglutes1.00infobox
SyneminBgeevastus lateralis muscle1.00infobox
SyneminBgeetail of epididymis1.00infobox
SyneminBgeeSkeletal muscle tissue of biceps brachii1.00infobox
SyneminBgeeoptic nerve1.00infobox
SyneminBgeeright ventricle1.00infobox
SyneminBgeedeltoid muscle1.00infobox
SyneminBgeetriceps brachii muscle1.00infobox
SyneminBgeeknee joint1.00infobox
SyneminBgeemedial head of gastrocnemius muscle1.00infobox
SyneminBgeetemporal muscle1.00infobox
SyneminBgeesternocleidomastoid muscle1.00infobox
SyneminBgeetibialis anterior muscle1.00infobox
SyneminBgeemuscle of thigh1.00infobox
SyneminBgeedigastric muscle1.00infobox
SyneminBgeeankle1.00infobox
SyneminBioGPSn/a1.00infobox
SyneminChr.Chromosome 15 (human)1.00infobox
SyneminChr.Chromosome 7 (mouse)1.00infobox
SyneminDatabasesNCBI: entry; OMA: entry1.00infobox
SyneminEnd99,135,593 bp1.00infobox
SyneminEnd67,409,490 bp1.00infobox
SyneminEnsemblENSG000001822531.00infobox
SyneminEntrez233361.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around Synemin bring nearby vocabulary together. In this analysis, examples include Human, Chicken and Filament. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • Synemin
    • Human
    • Chicken
    • Filament
    • Intermediate
    • Reported
    • Similar
    • Muscle
    • Gene
    • Synm
    • Function
    • Isoforms
    • Location
  • synemin
    • Human
    • Chicken
    • Filament
    • Intermediate
    • Reported
    • Similar
    • Muscle
    • Gene
    • Synm
    • Function
    • Isoforms
    • Location
  • protein
    • Muscle
    • Network
    • Structural
    • Cell
    • Desmin
    • Mechanical
    • Gene
    • Synm
    • Synemin
    • Encoded
    • End
    • Extracellular
  • intermediate filament
    • Filament
    • Intermediate
    • End
    • Family
    • Function
    • Mouse
    • Stress
    • Structural
    • Cell
    • Location
    • Similar
    • Skeletal
  • gene
    • Synm
    • Location
    • Chromosome
    • Bp
    • Chr
    • End
    • Function
    • Mouse
    • Human
    • Band
    • Protein
    • External
  • human papillomavirus
    • Chicken
    • Synemin
    • Location
    • Band
    • Synm
    • End
    • Mouse
    • Proteins
    • Reported
    • Similar
    • Protein
    • Stress
  • function
    • Location
    • Chromosome
    • Bp
    • Chr
    • Gene
    • Synm
    • End
    • Mouse
    • Stress
    • Structural
    • Cell
    • Intermediate
  • smooth muscle
    • Structural
    • Protein
    • Skeletal
    • End
    • Function
    • Mouse
    • Network
    • Stress
    • Cell
    • Location
    • Synemin
    • Band

Connections between topic areas Semantic bridges

For Synemin, one of the stronger structural bridges in this analysis connects Synemin with Overview. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
SyneminOverview · splits 24 ⟂ 7
SyneminHistory · splits 24 ⟂ 7
SyneminFunction · splits 25 ⟂ 6
SyneminCancer · splits 27 ⟂ 4
SyneminProperties · splits 28 ⟂ 3
SyneminSplice variants · splits 28 ⟂ 3

Map overview Semantic statistics

Synemin

Nodes31
Edges30
Triples102
Avg. degree1.94
Density0.064516
Components1

Source & methodology

TTTA analyzes the structure around Synemin to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as History, Function & Cancer, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — Synemin · EN edition · Analysis: TopicsToTalkAbout

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