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Desmosome: History & Regions

A desmosome (/ˈdɛzməˌsoʊm/; "binding body"), also known as a macula adherens (plural: maculae adherentes) (Latin for adhering spot), is a cell structure specialized for cell-to-cell adhesion. A type of junctional complex, they are localized spot-like adhesions randomly arranged on the lateral sides of plasma membranes. Desmosomes are one of the stronger…

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Desmosome topic overview

The analysis highlights History and Regions as prominent areas in the source structure around Desmosome.

Related topics
45
Source areas
4
Connected nodes
49
Extracted relationships
56
Concept neighborhoods
24
Bridge connections
49

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Clinical significance · 22 topics
Structure · 11 topics
Overview · 9 topics
History · 3 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

FMA
67412
Latin
Desmosoma Macula adhaerens
MeSH
D003896
TH
H1.00.01.1.02015

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Structure

Clinical significance

History

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How Desmosome connects Entity context

The extracted context around Desmosome shows recurring relationship patterns in the source. For example, Desmosome → ATP2C1, Blistering, Both, Desmoglein, Dsg1, Dsg3, Hailey, IgG, Loss, Pemphigus, PF, PV, Similar Another extracted example is Desmosome → Both, Desmoglein, Desmogleins, Desmosomes, DIFCs, Dsc-a, Extracellular, IDP, N-termini, ODP, The, The DIFCs, They. Use these groups to spot repeated connection types before inspecting the individual relationships.

Desmosome

Top relations

related to Blisters · 13
Desmosome → ATP2C1, Blistering, Both, Desmoglein, Dsg1, Dsg3, Hailey, IgG, Loss, Pemphigus, PF, PV, Similar
related to Structure · 13
Desmosome → Both, Desmoglein, Desmogleins, Desmosomes, DIFCs, Dsc-a, Extracellular, IDP, N-termini, ODP, The, The DIFCs, They
related to history · 10
Desmosome → Bizzozero, Combined, Giulio Bizzozero, Greek, He, In, Italian, Josef Schaffer, Neo-Latin, The
related to External links · 8
Desmosome → Boston University, Cell, Histology, Histology Learning System, Junctional Complex, LoyolaHisto/practical/epithelium/hp1-13, MedEd, Ultrastructure
related to Arrhythmogenic cardiomyopathy · 5
Desmosome → ACM, It, Mutations, Symptoms, The
FMA · 1
Desmosome → 67412
Latin · 1
Desmosome → Desmosoma Macula adhaerens
MeSH · 1
Desmosome → D003896
TH · 1
Desmosome → H1.00.01.1.02015
see also · 1
Desmosome → Arrhythmogenic

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

desmoglein desmoplakin desmocollin cell extracellular filaments adhesion cadherin plakoglobin proteins desmosomes also structure keratin domain membrane disease caused binding region

Desmosome relationships Subject–Predicate–Object triples

TTTA extracted 56 structured relationships around Desmosome. Examples in this analysis include Desmosome → FMA → 67412 and Desmosome → Latin → Desmosoma Macula adhaerens. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
DesmosomeFMA674121.00infobox
DesmosomeLatinDesmosoma Macula adhaerens1.00infobox
DesmosomeMeSHD0038961.00infobox
DesmosomeTHH1.00.01.1.020151.00infobox
pemphigus vulgarisinstance ofand heart palpitations and the condition is treated by implanting a small defibrillator device.BlistersBlistering diseases0.80text
pemphigus vulgarisinstance ofBlistersBlistering diseases0.80text
Desmosomerelated to Arrhythmogenic cardiomyopathyMutations0.60section
Desmosomerelated to Arrhythmogenic cardiomyopathyACM0.60section
Desmosomerelated to Arrhythmogenic cardiomyopathyIt0.60section
Desmosomerelated to Arrhythmogenic cardiomyopathyThe0.60section
Desmosomerelated to Arrhythmogenic cardiomyopathySymptoms0.60section
Desmosomerelated to BlistersBlistering0.60section

Related concept clusters Concept neighborhoods

The concept neighborhoods around Desmosome bring nearby vocabulary together. In this analysis, examples include Structure, Filaments and Desmoplakin. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • Desmosome
    • Structure
    • Filaments
    • Desmoplakin
    • Arrhythmogenic
    • Cardiomyopathy
    • Keratin
    • Cell
    • Cell-to-cell
    • Latin
    • Macula
    • Blisters
    • Plakophilin
  • desmosome
    • Structure
    • Filaments
    • Desmoplakin
    • Arrhythmogenic
    • Cardiomyopathy
    • Keratin
    • Cell
    • Cell-to-cell
    • Latin
    • Macula
    • Blisters
    • Plakophilin
  • cell adhesion
    • Cell-to-cell
    • Cadherin
    • Intracellular
    • Region
    • Adhesion
    • Cell
    • Membrane
    • Desmocollin
    • Extracellular
    • Proteins
    • Desmoglein
    • Latin
  • desmoglein
    • Region
    • Extracellular
    • Contains
    • Nm
    • Intracellular
    • Length
    • Plaque
    • Cadherin
    • Caused
    • Disease
    • Domain
    • Proteins
  • desmoglein 2
    • Region
    • Extracellular
    • Contains
    • Nm
    • Intracellular
    • Length
    • Plaque
    • Cadherin
    • Caused
    • Disease
    • Domain
    • Proteins
  • desmoglein 3
    • Region
    • Extracellular
    • Contains
    • Nm
    • Intracellular
    • Length
    • Plaque
    • Cadherin
    • Caused
    • Disease
    • Domain
    • Proteins
  • desmoglein 1
    • Region
    • Extracellular
    • Contains
    • Nm
    • Intracellular
    • Length
    • Plaque
    • Cadherin
    • Caused
    • Disease
    • Domain
    • Proteins
  • desmoglein 4
    • Region
    • Extracellular
    • Contains
    • Nm
    • Intracellular
    • Length
    • Plaque
    • Cadherin
    • Caused
    • Disease
    • Domain
    • Proteins

Connections between topic areas Semantic bridges

For Desmosome, one of the stronger structural bridges in this analysis connects Desmosome with Clinical significance. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
Desmosome — Clinical significance · splits 27 ⟂ 23
Desmosome — Structure · splits 38 ⟂ 12
Desmosome — Overview · splits 40 ⟂ 10
Desmosome — History · splits 46 ⟂ 4

Map overview Semantic statistics

Desmosome

Nodes50
Edges49
Triples56
Avg. degree1.96
Density0.04
Components1

Source & methodology

TTTA analyzes the structure around Desmosome to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as History & Regions, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — Desmosome · EN edition · Analysis: TopicsToTalkAbout

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