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Plectin is a giant protein found in nearly all mammalian cells which acts as a link between the three main components of the cytoskeleton: actin microfilaments, microtubules and intermediate filaments. In addition, plectin links the cytoskeleton to junctions found in the plasma membrane that structurally connect different cells. By holding these…
The analysis highlights Structure, Function and Clinical significance as prominent areas in the source structure around Plectin.
Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.
Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.
High-confidence facts extracted from structured source data. Use them as anchors for further research.
Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.
Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.
The extracted context around Plectin shows recurring relationship patterns in the source. For example, Plectin → actin binding, ankyrin binding, brush border, cadherin binding, cell junction, contractile fiber, costamere, cytoplasm, cytoskeletal protein binding, cytoskeleton, cytoskeleton organization, cytosol, extracellular exosome, extracellular matrix, focal adhesion, hemidesmosome, hemidesmosome assembly, intermediate filament, intermediate filament cytoskeleton, intermediate filament cytoskeleton organization Another extracted example is Plectin → ankle, apex of heart, body of tongue, digastric muscle, endothelial cell of lymphatic vessel, external carotid artery, gastric mucosa, gastrocnemius muscle, internal carotid artery, muscle of thigh, nipple, right coronary artery, Skeletal muscle tissue of rectus abdominis, soleus muscle, sternocleidomastoid muscle, stromal cell of endometrium, sural nerve, temporal muscle, triceps brachii muscle, vastus lateralis muscle. Use these groups to spot repeated connection types before inspecting the individual relationships.
Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.
intermediate bp cells cytoskeleton protein chr human band also actin chromosome plec muscle filaments found membrane external mouse filament gene
TTTA extracted 130 structured relationships around Plectin. Examples in this analysis include Plectin → Aliases → PLEC, EBS1, EBSMD, EBSND, EBSO, EBSOG, EBSPA, HD1, LGMD2Q, PCN, PLEC1, PLEC1b, PLTN, plectin, LGMDR17, EBS5D, EBS5C, EBS5B, EBS5A and Plectin → Available structures → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1MB8, 2ODU, 2ODV, 3F7P, 3PDY, 3PE0, 4GDO, 4Q58, 4Q59, 2N03, 5J1H, 5J1G, 5J1I. The table shows each extracted connection, where it came from and its confidence.
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| Plectin | Aliases | PLEC, EBS1, EBSMD, EBSND, EBSO, EBSOG, EBSPA, HD1, LGMD2Q, PCN, PLEC1, PLEC1b, PLTN, plectin, LGMDR17, EBS5D, EBS5C, EBS5B, EBS5A | 1.00 | infobox |
| Plectin | Available structures | Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1MB8, 2ODU, 2ODV, 3F7P, 3PDY, 3PE0, 4GDO, 4Q58, 4Q59, 2N03, 5J1H, 5J1G, 5J1I | 1.00 | infobox |
| Plectin | Band | 8q24.3 | 1.00 | infobox |
| Plectin | Band | 15 D3|15 35.48 cM | 1.00 | infobox |
| Plectin | Bgee | sural nerve | 1.00 | infobox |
| Plectin | Bgee | muscle of thigh | 1.00 | infobox |
| Plectin | Bgee | gastrocnemius muscle | 1.00 | infobox |
| Plectin | Bgee | stromal cell of endometrium | 1.00 | infobox |
| Plectin | Bgee | apex of heart | 1.00 | infobox |
| Plectin | Bgee | body of tongue | 1.00 | infobox |
| Plectin | Bgee | right coronary artery | 1.00 | infobox |
| Plectin | Bgee | gastric mucosa | 1.00 | infobox |
| Plectin | Bgee | nipple | 1.00 | infobox |
| Plectin | Bgee | Skeletal muscle tissue of rectus abdominis | 1.00 | infobox |
| Plectin | Bgee | ankle | 1.00 | infobox |
| Plectin | Bgee | internal carotid artery | 1.00 | infobox |
| Plectin | Bgee | external carotid artery | 1.00 | infobox |
| Plectin | Bgee | soleus muscle | 1.00 | infobox |
| Plectin | Bgee | temporal muscle | 1.00 | infobox |
| Plectin | Bgee | endothelial cell of lymphatic vessel | 1.00 | infobox |
| Plectin | Bgee | digastric muscle | 1.00 | infobox |
| Plectin | Bgee | triceps brachii muscle | 1.00 | infobox |
| Plectin | Bgee | vastus lateralis muscle | 1.00 | infobox |
| Plectin | Bgee | sternocleidomastoid muscle | 1.00 | infobox |
| Plectin | BioGPS | n/a | 1.00 | infobox |
| Plectin | Chr. | Chromosome 8 (human) | 1.00 | infobox |
| Plectin | Chr. | Chromosome 15 (mouse) | 1.00 | infobox |
| Plectin | Databases | NCBI: entry; OMA: entry | 1.00 | infobox |
| Plectin | End | 143,976,734 bp | 1.00 | infobox |
| Plectin | End | 76,116,774 bp | 1.00 | infobox |
The concept neighborhoods around Plectin bring nearby vocabulary together. In this analysis, examples include Intermediate, Cytoskeleton and Cells. Use the clusters to find adjacent concepts and terminology that may deserve separate research.
For Plectin, one of the stronger structural bridges in this analysis connects Plectin with Structure. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.
TTTA analyzes the structure around Plectin to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Structure, Function & Clinical significance, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.
Source: Wikipedia — Plectin · EN edition · Analysis: TopicsToTalkAbout