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Peripherin

Peripherin is a type III intermediate filament protein expressed mainly in neurons of the peripheral nervous system. It is also found in neurons of the central nervous system that have projections toward peripheral structures, such as spinal motor neurons. Its size, structure, and sequence/location of protein motifs is similar to other type III…

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Aliases
PRPH, NEF4, PRPH1, peripherin
Band
12q13.12 · 15 F1|15 55.72 cM
Bgee
spinal ganglia · trigeminal ganglion · sperm · left testis · right testis
BioGPS
n/a
Chr.
Chromosome 12 (human) · Chromosome 15 (mouse)
Databases
NCBI: entry; OMA: entry

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Overview

History

Gene

Tissue distribution

Structure

Function

Regulation

Clinical significance

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Map overview Semantic statistics

Peripherin

Nodes80
Edges79
Triples163
Avg. degree1.98
Density0.025
Components1

How this topic connects Entity context

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Peripherin

Top relations

Bgee · 18
Peripherin → anterior horn of spinal cord, external carotid artery, facial motor nucleus, gallbladder, gonad, left testis, lumbar spinal ganglion, motor neuron, muscle layer of sigmoid colon, optic nerve, right testis, sperm, spinal ganglia, superior cervical ganglion, superior surface of tongue, sympathetic trunk, testicle, trigeminal ganglion
RNA expression pattern · 18
Peripherin → anterior horn of spinal cord, external carotid artery, facial motor nucleus, gallbladder, gonad, left testis, lumbar spinal ganglion, motor neuron, muscle layer of sigmoid colon, optic nerve, right testis, sperm, spinal ganglia, superior cervical ganglion, superior surface of tongue, sympathetic trunk, testicle, trigeminal ganglion
related to Function · 16
Peripherin → As, During, Early, Expression, Future, However, IB4, IFs, III, III IFs, In, IV, L5, PC12, The, This
related to Gene · 12
Peripherin → Comparison, DNAs, E-F, EMBL X59840, GenBank L14565, GenBank M26232, Hox, PRPH, See Hox, The, This, Xenopus
related to Structure · 12
Peripherin → All, C-terminal, IFs, III, N-terminal, NF-L, Studies, The, These, They, This, Type III
related to Regulation · 11
Peripherin → E10, It, JAK-STAT, Nerve, NGF, NGF-induced, PC12, Post, TATA, The, This
related to Mutations · 9
Peripherin → ALS, Consequently, Experiments, In, PRPH, The, The PRPH, This, Though
related to Clinical significance · 8
Peripherin → Hirschsprung, However, In, Patients, S-100, See, Since, To
Gene ontology · 7
Peripherin → extracellular exosome, intermediate filament, intermediate filament cytoskeleton organization, membrane, protein binding, structural molecule activity, type III intermediate filament
related to Tissue distribution · 7
Peripherin → It, LDT, PPT, Some, These, They, This

Important terminology Word statistics

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Important terminology

protein also intermediate neurons filament gene human cells role prph type lateral found sclerosis iii proteins mouse expression peripheral bp

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
PeripherinAliasesPRPH, NEF4, PRPH1, peripherin1.00infobox
PeripherinBand12q13.121.00infobox
PeripherinBand15 F1|15 55.72 cM1.00infobox
PeripherinBgeespinal ganglia1.00infobox
PeripherinBgeetrigeminal ganglion1.00infobox
PeripherinBgeesperm1.00infobox
PeripherinBgeeleft testis1.00infobox
PeripherinBgeeright testis1.00infobox
PeripherinBgeemuscle layer of sigmoid colon1.00infobox
PeripherinBgeegonad1.00infobox
PeripherinBgeetesticle1.00infobox
PeripherinBgeeoptic nerve1.00infobox
PeripherinBgeesympathetic trunk1.00infobox
PeripherinBgeesuperior cervical ganglion1.00infobox
PeripherinBgeefacial motor nucleus1.00infobox
PeripherinBgeelumbar spinal ganglion1.00infobox
PeripherinBgeeexternal carotid artery1.00infobox
PeripherinBgeemotor neuron1.00infobox
PeripherinBgeesuperior surface of tongue1.00infobox
PeripherinBgeegallbladder1.00infobox
PeripherinBgeeanterior horn of spinal cord1.00infobox
PeripherinBioGPSn/a1.00infobox
PeripherinChr.Chromosome 12 (human)1.00infobox
PeripherinChr.Chromosome 15 (mouse)1.00infobox
PeripherinDatabasesNCBI: entry; OMA: entry1.00infobox
PeripherinEnd49,298,686 bp1.00infobox
PeripherinEnd98,956,859 bp1.00infobox
PeripherinEnsemblENSG000001354061.00infobox
PeripherinEntrez56301.00infobox
PeripherinExternal IDsOMIM: 170710; MGI: 97774; GeneCards: PRPH1.00infobox

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