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Keratin 14: Pathology & Overview

Keratin 14 is a member of the type I keratin family of intermediate filament proteins. Keratin 14 was the first type I keratin sequence determined. Keratin 14 is also known as cytokeratin-14 (CK-14) or keratin-14 (KRT14). In humans it is encoded by the KRT14 gene.

Language: English [EN]
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Keratin 14 topic overview

The analysis highlights Pathology and Overview as prominent areas in the source structure around Keratin 14.

Related topics
10
Source areas
2
Connected nodes
12
Extracted relationships
85
Concept neighborhoods
11
Bridge connections
12

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Overview · 8 topics
Pathology · 2 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases
KRT14, CK14, EBS3, EBS4, K14, NFJ, keratin 14, EBS1D, EBS1, EBS1B, EBS1A, EBS1C
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes3TNU
Band
17q21.2 · 11 63.43 cM|11 D
Bgee
gingival epithelium · skin of arm · skin of thigh · nipple · vulva
BioGPS
More reference expression data
Chr.
Chromosome 17 (human) · Chromosome 11 (mouse)

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Pathology

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How Keratin 14 connects Entity context

The extracted context around Keratin 14 shows recurring relationship patterns in the source. For example, Keratin 14 → ageing, basal part of cell, cell periphery, cornification, cytoplasm, cytosol, epidermis development, epithelial cell differentiation, extracellular exosome, hair cycle, hemidesmosome assembly, intermediate filament, intermediate filament bundle assembly, intracellular anatomical structure, keratin filament, keratin filament binding, keratinization, nucleus, protein binding, response to ionizing radiation Another extracted example is Keratin 14 → body of tongue, cervix, conjunctival fornix, cornea, esophagus, gingival epithelium, hair follicle, human penis, lip, molar, nipple, skin of abdomen, skin of arm, skin of back, skin of external ear, skin of hip, skin of thigh, umbilical cord, vulva. Use these groups to spot repeated connection types before inspecting the individual relationships.

Keratin 14

Top relations

Gene ontology · 23
Keratin 14 → ageing, basal part of cell, cell periphery, cornification, cytoplasm, cytosol, epidermis development, epithelial cell differentiation, extracellular exosome, hair cycle, hemidesmosome assembly, intermediate filament, intermediate filament bundle assembly, intracellular anatomical structure, keratin filament, keratin filament binding, keratinization, nucleus, protein binding, response to ionizing radiation
Bgee · 19
Keratin 14 → body of tongue, cervix, conjunctival fornix, cornea, esophagus, gingival epithelium, hair follicle, human penis, lip, molar, nipple, skin of abdomen, skin of arm, skin of back, skin of external ear, skin of hip, skin of thigh, umbilical cord, vulva
RNA expression pattern · 19
Keratin 14 → body of tongue, cervix, conjunctival fornix, cornea, esophagus, gingival epithelium, hair follicle, human penis, lip, molar, nipple, skin of abdomen, skin of arm, skin of back, skin of external ear, skin of hip, skin of thigh, umbilical cord, vulva
Band · 2
Keratin 14 → 11 63.43 cM|11 D, 17q21.2
Chr. · 2
Keratin 14 → Chromosome 11 (mouse), Chromosome 17 (human)
End · 2
Keratin 14 → 100,098,374 bp, 41,586,895 bp
Aliases · 1
Keratin 14 → KRT14, CK14, EBS3, EBS4, K14, NFJ, keratin 14, EBS1D, EBS1, EBS1B, EBS1A, EBS1C
Available structures · 1
Keratin 14 → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes3TNU
BioGPS · 1
Keratin 14 → More reference expression data
Databases · 1
Keratin 14 → NCBI: entry; OMA: entry

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

keratin 14 bp krt14 chr human band gene chromosome 17 type external location cytoskeleton also mouse intermediate filament epithelial search

Keratin 14 relationships Subject–Predicate–Object triples

TTTA extracted 85 structured relationships around Keratin 14. Examples in this analysis include Keratin 14 → Aliases → KRT14, CK14, EBS3, EBS4, K14, NFJ, keratin 14, EBS1D, EBS1, EBS1B, EBS1A, EBS1C and Keratin 14 → Available structures → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes3TNU. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
Keratin 14AliasesKRT14, CK14, EBS3, EBS4, K14, NFJ, keratin 14, EBS1D, EBS1, EBS1B, EBS1A, EBS1C1.00infobox
Keratin 14Available structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes3TNU1.00infobox
Keratin 14Band17q21.21.00infobox
Keratin 14Band11 63.43 cM|11 D1.00infobox
Keratin 14Bgeegingival epithelium1.00infobox
Keratin 14Bgeeskin of arm1.00infobox
Keratin 14Bgeeskin of thigh1.00infobox
Keratin 14Bgeenipple1.00infobox
Keratin 14Bgeevulva1.00infobox
Keratin 14Bgeehuman penis1.00infobox
Keratin 14Bgeeskin of hip1.00infobox
Keratin 14Bgeehair follicle1.00infobox
Keratin 14Bgeeskin of abdomen1.00infobox
Keratin 14Bgeebody of tongue1.00infobox
Keratin 14Bgeeskin of external ear1.00infobox
Keratin 14Bgeelip1.00infobox
Keratin 14Bgeemolar1.00infobox
Keratin 14Bgeeskin of back1.00infobox
Keratin 14Bgeeesophagus1.00infobox
Keratin 14Bgeecervix1.00infobox
Keratin 14Bgeeconjunctival fornix1.00infobox
Keratin 14Bgeecornea1.00infobox
Keratin 14Bgeeumbilical cord1.00infobox
Keratin 14BioGPSMore reference expression data1.00infobox
Keratin 14Chr.Chromosome 17 (human)1.00infobox
Keratin 14Chr.Chromosome 11 (mouse)1.00infobox
Keratin 14DatabasesNCBI: entry; OMA: entry1.00infobox
Keratin 14End41,586,895 bp1.00infobox
Keratin 14End100,098,374 bp1.00infobox
Keratin 14EnsemblENSG000001868471.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around Keratin 14 bring nearby vocabulary together. In this analysis, examples include Type, Krt14 and Also. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • Keratin 14
    • Type
    • Krt14
    • Also
    • Bullosa
    • Cytoskeleton
    • Entry
    • Epidermolysis
    • Epithelial
    • External
    • Filament
    • Intermediate
    • Keratins
  • keratin 14
    • Type
    • Krt14
    • Also
    • Bullosa
    • Cytoskeleton
    • Entry
    • Epidermolysis
    • Epithelial
    • External
    • Filament
    • Intermediate
    • Keratins
  • type i keratin
    • Keratin
    • Type
    • Krt14
    • Family
    • Heterodimer
    • Member
    • Proteins
    • Also
    • Bullosa
    • Cytoskeleton
    • Entry
    • Epidermolysis
  • intermediate filament proteins
    • Filament
    • Intermediate
    • Member
    • Proteins
    • Bullosa
    • Cm
    • Cytoskeleton
    • End
    • Entry
    • Epidermolysis
    • Epithelial
    • External
  • keratin 5
    • Type
    • Krt14
    • Also
    • Bullosa
    • Cytoskeleton
    • Entry
    • Epidermolysis
    • Epithelial
    • External
    • Filament
    • Intermediate
    • Keratins
  • cytoskeleton
    • Epithelial
    • Heterodimer
    • Bullosa
    • Cm
    • End
    • Entry
    • Epidermolysis
    • External
    • Filament
    • Intermediate
    • Keratins
    • Mouse
  • epithelial cells
    • Heterodimer
    • Bullosa
    • Cm
    • End
    • Entry
    • Epidermolysis
    • External
    • Filament
    • Intermediate
    • Keratins
    • Mouse
    • Ncbi
  • gene
    • Location
    • Chromosome
    • Human
    • Krt14
    • Bp
    • Chr
    • Cm
    • End
    • External
    • Mouse
    • Search
    • Band

Connections between topic areas Semantic bridges

For Keratin 14, one of the stronger structural bridges in this analysis connects Keratin 14 with Overview. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
Keratin 14Overview · splits 4 ⟂ 9
Keratin 14Pathology · splits 10 ⟂ 3

Map overview Semantic statistics

Keratin 14

Nodes13
Edges12
Triples85
Avg. degree1.85
Density0.153846
Components1

Source & methodology

TTTA analyzes the structure around Keratin 14 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Pathology & Overview, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — Keratin 14 · EN edition · Analysis: TopicsToTalkAbout

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