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Vimentin

Vimentin is a structural protein that in humans is encoded by the VIM gene. Its name comes from the Latin vimentum, meaning an osier, withy (array of flexible rods).

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Aliases
VIM, CTRCT30, HEL113, vimentin
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1GK4, 1GK6, 1GK7, 3G1E, 3KLT, 3S4R, 3SSU, 3SWK, 3TRT, 3UF1, 4MCY, 4MCZ, 4MD0, 4MD5, 4MDJ, 4YPC, 4YV3
Band
10p13 · 2 A1|2 10.04 cM
Bgee
ventricular zone · Descending thoracic aorta · right coronary artery · synovial membrane · spinal ganglia
BioGPS
More reference expression data
Chr.
Chromosome 10 (human) · Chromosome 2 (mouse)

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Structure

Function

Clinical significance

Interactions

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Map overview Semantic statistics

Vimentin

Nodes62
Edges61
Triples139
Avg. degree1.97
Density0.032258
Components1

How this topic connects Entity context

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Vimentin

Top relations

Gene ontology · 44
Vimentin → astrocyte development, Bergmann glial cell differentiation, cell leading edge, cell projection, cellular response to interferon-gamma, cellular response to lipopolysaccharide, cellular response to muramyl dipeptide, cytokine-mediated signaling pathway, cytoplasm, cytoskeleton, cytosol, double-stranded RNA binding, extracellular exosome, extracellular matrix, focal adhesion, identical protein binding, intermediate filament, intermediate filament organization, intermediate filament-based process, keratin filament binding
Bgee · 19
Vimentin → ascending aorta, decidua, dermis, Descending thoracic aorta, endothelial cell of lymphatic vessel, external carotid artery, Gonadal ridge, internal carotid artery, left lung lobe, popliteal artery, right coronary artery, semi-lunar valve, spinal ganglia, stroma of bone marrow, synovial membrane, tibial arteries, tibial nerve, tunica media of zone of aorta, ventricular zone
RNA expression pattern · 19
Vimentin → ascending aorta, decidua, dermis, Descending thoracic aorta, endothelial cell of lymphatic vessel, external carotid artery, Gonadal ridge, internal carotid artery, left lung lobe, popliteal artery, right coronary artery, semi-lunar valve, spinal ganglia, stroma of bone marrow, synovial membrane, tibial arteries, tibial nerve, tunica media of zone of aorta, ventricular zone
related to Clinical significance · 10
Vimentin → Anti-citrullinated, Barrett's, DNA, Downregulation, High, It, Methylation, SARS-CoV-2, See, Statistically
related to Function · 8
Vimentin → It, Moreover, On, Scientists, The, Therefore, This, Transgenic
related to Structure · 7
Vimentin → Eight, In, The, Two, ULF, ULFs, While
is a · 4
Vimentin → cytoskeletal component responsible for maintaining cell integrity, major cytoskeletal component of mesenchymal cells, structural protein that in humans is encoded by the VIM gene, type III intermediate filament
Band · 2
Vimentin → 10p13, 2 A1|2 10.04 cM
Chr. · 2
Vimentin → Chromosome 10 (human), Chromosome 2 (mouse)
End · 2
Vimentin → 13,587,637 bp, 17,237,593 bp

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Important terminology

cells gene cell protein found bp filament intermediate expressed chr human band also type proteins chromosome 10 vim cytoskeleton external

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
VimentinAliasesVIM, CTRCT30, HEL113, vimentin1.00infobox
VimentinAvailable structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1GK4, 1GK6, 1GK7, 3G1E, 3KLT, 3S4R, 3SSU, 3SWK, 3TRT, 3UF1, 4MCY, 4MCZ, 4MD0, 4MD5, 4MDJ, 4YPC, 4YV31.00infobox
VimentinBand10p131.00infobox
VimentinBand2 A1|2 10.04 cM1.00infobox
VimentinBgeeventricular zone1.00infobox
VimentinBgeeDescending thoracic aorta1.00infobox
VimentinBgeeright coronary artery1.00infobox
VimentinBgeesynovial membrane1.00infobox
VimentinBgeespinal ganglia1.00infobox
VimentinBgeepopliteal artery1.00infobox
VimentinBgeetibial arteries1.00infobox
VimentinBgeedecidua1.00infobox
VimentinBgeeascending aorta1.00infobox
VimentinBgeetibial nerve1.00infobox
VimentinBgeeendothelial cell of lymphatic vessel1.00infobox
VimentinBgeeleft lung lobe1.00infobox
VimentinBgeedermis1.00infobox
VimentinBgeeGonadal ridge1.00infobox
VimentinBgeeexternal carotid artery1.00infobox
VimentinBgeetunica media of zone of aorta1.00infobox
VimentinBgeestroma of bone marrow1.00infobox
VimentinBgeeinternal carotid artery1.00infobox
VimentinBgeesemi-lunar valve1.00infobox
VimentinBioGPSMore reference expression data1.00infobox
VimentinChr.Chromosome 10 (human)1.00infobox
VimentinChr.Chromosome 2 (mouse)1.00infobox
VimentinDatabasesNCBI: entry; OMA: entry1.00infobox
VimentinEnd17,237,593 bp1.00infobox
VimentinEnd13,587,637 bp1.00infobox
VimentinEnsemblENSG000000260251.00infobox

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