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HDAC9: Research, Interactions & Overview

Histone deacetylase 9 is an enzyme that in humans is encoded by the HDAC9 gene.

Language: English [EN]
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HDAC9 topic overview

The analysis highlights Research, Interactions and Overview as prominent areas in the source structure around HDAC9.

Related topics
27
Source areas
3
Connected nodes
30
Extracted relationships
169
Concept neighborhoods
9
Bridge connections
30

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Research · 15 topics
Interactions · 10 topics
Overview · 2 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

3.5.1.98
Aliases
HDAC9, HD7, HD7b, HD9, HDAC, HDAC7, HDAC7B, HDAC9B, HDAC9FL, HDRP, MITR, histone deacetylase 9
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1TQE
Band
7p21.1 · 12|12 A3
Bgee
oocyte · monocyte · secondary oocyte · endothelial cell · Epithelium of choroid plexus
BioGPS
n/a

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Research

Interactions

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How HDAC9 connects Entity context

The extracted context around HDAC9 shows recurring relationship patterns in the source. For example, HDAC9 → B cell activation, B cell differentiation, cellular response to insulin stimulus, cholesterol homeostasis, chromatin organization, cytoplasm, development of the heart, histone deacetylase activity, histone deacetylase activity (H4-K16 specific), histone deacetylase binding, histone deacetylase complex, histone deacetylation, histone H3 deacetylation, histone H4 deacetylation, histone H4-K16 deacetylation, histone methyltransferase complex, hydrolase activity, inflammatory response, metal ion binding, NAD-dependent histone deacetylase activity (H3-K14 specific) Another extracted example is HDAC9 → ascending aorta, dentate gyrus of hippocampal formation granule cell, endothelial cell, Epithelium of choroid plexus, ganglionic eminence, gonad, interventricular septum, left ventricle, monocyte, neural layer of retina, oocyte, parotid gland, piriform cortex, Region I of hippocampus proper, secondary oocyte, Skeletal muscle tissue of rectus abdominis, ventricular zone, visual cortex, zygote. Use these groups to spot repeated connection types before inspecting the individual relationships.

HDAC9

Top relations

Gene ontology · 39
HDAC9 → B cell activation, B cell differentiation, cellular response to insulin stimulus, cholesterol homeostasis, chromatin organization, cytoplasm, development of the heart, histone deacetylase activity, histone deacetylase activity (H4-K16 specific), histone deacetylase binding, histone deacetylase complex, histone deacetylation, histone H3 deacetylation, histone H4 deacetylation, histone H4-K16 deacetylation, histone methyltransferase complex, hydrolase activity, inflammatory response, metal ion binding, NAD-dependent histone deacetylase activity (H3-K14 specific)
Bgee · 19
HDAC9 → ascending aorta, dentate gyrus of hippocampal formation granule cell, endothelial cell, Epithelium of choroid plexus, ganglionic eminence, gonad, interventricular septum, left ventricle, monocyte, neural layer of retina, oocyte, parotid gland, piriform cortex, Region I of hippocampus proper, secondary oocyte, Skeletal muscle tissue of rectus abdominis, ventricular zone, visual cortex, zygote
RNA expression pattern · 19
HDAC9 → ascending aorta, dentate gyrus of hippocampal formation granule cell, endothelial cell, Epithelium of choroid plexus, ganglionic eminence, gonad, interventricular septum, left ventricle, monocyte, neural layer of retina, oocyte, parotid gland, piriform cortex, Region I of hippocampus proper, secondary oocyte, Skeletal muscle tissue of rectus abdominis, ventricular zone, visual cortex, zygote
related to Function · 14
HDAC9 → CtBP, DNA, HDACs, Histone, Histones, II HDACs, It, MEF2, MITR, Multiple, The, The MITR, This, Xenopus
related to ischemic brain injury · 11
HDAC9 → CTCF, CTCF/miR-383-5p/HDAC9, HDCA9, Histone, In, MCAO, Neurod1, OGD, OGD-induced, Silencing, Thus
related to intracranial aneurysm · 10
HDAC9 → BCL2L11, CDKN2B-AS1, Chinese, Data, IA, MMP-2, MMP-9, Oppositely, RP1, VEGF
related to Glioblastoma · 9
HDAC9 → Also, EGFR, HDAC9-knockdown, Hippo, Knockdown, Knockdown HDAC9, TAZ, TAZ-mediated EGFR, We
related to Motor innervation control of gene expression · 8
HDAC9 → AChR, By, Forced, Hdac9-null, HDACs, MEF2, Motor, These
related to Interactions · 7
HDAC9 → BTG2, CBX5, HDAC3, IKK1, IKK2, Myocyte-specific, SIN3A
related to External links · 6
HDAC9 → Medicine, Medicine Medical Subject Headings, MeSH, National Library, This, United States National Library

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

gene histone deacetylase expression bp protein human chromosome factor chr band mir-92a silencing encoded ischemic brain injury mouse mitr cell

HDAC9 relationships Subject–Predicate–Object triples

TTTA extracted 169 structured relationships around HDAC9. Examples in this analysis include HDAC9 → 3.5.1.98 → ↗ and HDAC9 → Aliases → HDAC9, HD7, HD7b, HD9, HDAC, HDAC7, HDAC7B, HDAC9B, HDAC9FL, HDRP, MITR, histone deacetylase 9. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
HDAC93.5.1.981.00infobox
HDAC9AliasesHDAC9, HD7, HD7b, HD9, HDAC, HDAC7, HDAC7B, HDAC9B, HDAC9FL, HDRP, MITR, histone deacetylase 91.00infobox
HDAC9Available structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1TQE1.00infobox
HDAC9Band7p21.11.00infobox
HDAC9Band12|12 A31.00infobox
HDAC9Bgeeoocyte1.00infobox
HDAC9Bgeemonocyte1.00infobox
HDAC9Bgeesecondary oocyte1.00infobox
HDAC9Bgeeendothelial cell1.00infobox
HDAC9BgeeEpithelium of choroid plexus1.00infobox
HDAC9Bgeeparotid gland1.00infobox
HDAC9Bgeeganglionic eminence1.00infobox
HDAC9BgeeSkeletal muscle tissue of rectus abdominis1.00infobox
HDAC9Bgeeventricular zone1.00infobox
HDAC9Bgeegonad1.00infobox
HDAC9Bgeeinterventricular septum1.00infobox
HDAC9Bgeeneural layer of retina1.00infobox
HDAC9Bgeezygote1.00infobox
HDAC9Bgeedentate gyrus of hippocampal formation granule cell1.00infobox
HDAC9BgeeRegion I of hippocampus proper1.00infobox
HDAC9Bgeeascending aorta1.00infobox
HDAC9Bgeevisual cortex1.00infobox
HDAC9Bgeepiriform cortex1.00infobox
HDAC9Bgeeleft ventricle1.00infobox
HDAC9BioGPSn/a1.00infobox
HDAC9Chr.Chromosome 7 (human)1.00infobox
HDAC9Chr.Chromosome 12 (mouse)1.00infobox
HDAC9DatabasesNCBI: entry; OMA: entry1.00infobox
HDAC9End19,002,416 bp1.00infobox
HDAC9End34,967,094 bp1.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around HDAC9 bring nearby vocabulary together. In this analysis, examples include Expression, Silencing and Histone. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • HDAC9
    • Expression
    • Silencing
    • Histone
    • Brain
    • Ia
    • Injury
    • Ischemic
    • Pathway
    • Factor
    • Apoptosis
    • Inflammatory
    • Mir-92a
  • hdac9
    • Expression
    • Silencing
    • Histone
    • Brain
    • Ia
    • Injury
    • Ischemic
    • Pathway
    • Factor
    • Apoptosis
    • Inflammatory
    • Mir-92a
  • gene
    • Mouse
    • Location
    • Histone
    • Bp
    • Chr
    • Genes
    • Human
    • Mitr
    • Chromosome
    • Protein
    • Expression
    • Activity
  • ischemic brain injury
    • Injury
    • Ischemic
    • Mir-20a
    • May
    • Silencing
    • Hdac9
    • Deacetylase
    • Glioblastoma
    • Location
    • Activity
    • Apoptosis
    • Histone
  • myocyte-specific enhancer factor 2a
    • Inflammatory
    • Acetylation
    • Apoptosis
    • Muscle
    • Vitro
    • Silencing
    • Histone
    • Hdac9
    • Location
    • Mef2
    • Mir-20a
    • Regulation
  • glioblastoma
    • Location
    • Activity
    • Bp
    • Chr
    • Human
    • Injury
    • Ischemic
    • Mitr
    • Pathway
    • Chromosome
    • Hdac9
    • Expression
  • skeletal muscle
    • Acetylation
    • Regulation
    • Genes
    • Mef2
    • Hdacs
    • Play
    • Role
    • Protein
  • mir-92a
    • Silencing

Connections between topic areas Semantic bridges

For HDAC9, one of the stronger structural bridges in this analysis connects HDAC9 with Research. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
HDAC9Research · splits 15 ⟂ 16
HDAC9Interactions · splits 20 ⟂ 11
HDAC9Overview · splits 28 ⟂ 3

Map overview Semantic statistics

HDAC9

Nodes31
Edges30
Triples169
Avg. degree1.94
Density0.064516
Components1

Source & methodology

TTTA analyzes the structure around HDAC9 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Research, Interactions & Overview, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — HDAC9 · EN edition · Analysis: TopicsToTalkAbout

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