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Desogestrel

Desogestrel is a progestin medication which is used in birth control pills. It is also used in the treatment of menopausal symptoms in women. The medication is available and used alone or in combination with an estrogen. It is taken by mouth.

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3D model (JSmol)
Interactive image
AHFS/Drugs.com
Multum Consumer Information
ATC code
G03AC09 (WHO)
Bioavailability
76% (range 40–100%)
CAS Number
54024-22-5 Y
ChEBI
CHEBI:4453 Y

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Overview

Medical uses

Contraindications

Side effects

Overdose

Interactions

Pharmacology

Chemistry

History

Society and culture

Research

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Map overview Semantic statistics

Desogestrel

Nodes238
Edges237
Triples177
Avg. degree1.99
Density0.008403
Components1

How this topic connects Entity context

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Desogestrel

Top relations

related to Brand names · 41
Desogestrel → Alenvona, Apri, Azalia, Azurette, Bekyree, Caziant, Cerazette, Cerelle, Cesia, Cyclessa, Cyred, Denise, Desirett, Desogen, Diamilla, Emoquette, Enskyce, Feanolla, Gedarel, Gracial
related to Pharmacokinetics · 17
Desogestrel → Accumulation, C11, C3, CYP3A4, Etonogestrel, Following, Hydroxylation, It, Neither, P450, P450-dependent, Peak, SHBG, Steady-state, The, This, While
related to Controversy · 16
Desogestrel → Apri-28, Cyclessa, Desogen, Drug Administration, Food, In, In February, Kariva, Medications, Mircette, Most, Ortho-Cept, Public Citizen, Reclipsen, United States, Velivet
related to Availability · 14
Desogestrel → Asia, Australia, Canada, European, In, Ireland, July, Latin America, New Zealand, Pharmacists, South Africa, UK, United Kingdom, United States
related to history · 10
Desogestrel → Along, Although, C11, Desogen, Europe, It, Marvelon, Netherlands, Organon International, United States
related to Interactions · 10
Desogestrel → CYP3A4, Examples, HCV, HIV/AIDS, Hormonal, Inducers, John's Wort, Many, St, This
related to Generic names · 9
Desogestrel → BANTooltip British Approved Name, DCFTooltip Dénomination Commune Française, DCITTooltip Denominazione Comune Italiana, INNTooltip International Nonproprietary Name, JANTooltip Japanese Accepted Name, Name, ORG-2969, USANTooltip United States Adopted, While
has effect · 8
Desogestrel → Breast, Common, HDLTooltip, However, In, LDLTooltip, Serious, Uncommon
is a · 4
Desogestrel → C3 deketo analogue of etonogestrel and the C3 deketo and C11 methylene analogue of levonorgestrel.SynthesisA chemical synthesis of desogestrel has been published.Synthetic probl…, prodrug of etonogestrel, progestin, progestin medication which is used in birth control pills
related to Contraindications · 4
Desogestrel → Allergy, Contraindications, Jaundice, Unexplained

Important terminology Word statistics

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Important terminology

etonogestrel effects activity used available affinity androgenic may day ethinylestradiol μg levels also oral progestogenic testosterone progesterone norethisterone women combination

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Desogestrel3D model (JSmol)Interactive image1.00infobox
DesogestrelAHFS/Drugs.comMultum Consumer Information1.00infobox
DesogestrelATC codeG03AC09 (WHO)1.00infobox
DesogestrelBioavailability76% (range 40–100%)1.00infobox
DesogestrelCAS Number54024-22-5 Y1.00infobox
DesogestrelChEBICHEBI:4453 Y1.00infobox
DesogestrelChEMBLChEMBL1533 Y1.00infobox
DesogestrelChemSpider37400 Y1.00infobox
DesogestrelCompTox Dashboard (EPA)DTXSID60228981.00infobox
DesogestrelDrug classProgestogen1.00infobox
DesogestrelDrugBankDB00304 Y1.00infobox
DesogestrelECHA InfoCard100.053.5551.00infobox
DesogestrelElimination half-lifeDesogestrel: 1.5 hours Etonogestrel: 21–38 hrs1.00infobox
DesogestrelExcretionUrine: 50% Feces: 35%1.00infobox
DesogestrelFormulaC22H30O1.00infobox
DesogestrelIUPHAR/BPS70651.00infobox
DesogestrelKEGGD02367 Y1.00infobox
DesogestrelLegal statusUK: POM (Prescription only) / P1.00infobox
DesogestrelLegal statusUS: ℞-only1.00infobox
DesogestrelLicense dataUS DailyMed: Desogestrel1.00infobox
DesogestrelMedlinePlusa6010501.00infobox
DesogestrelMelting point109 to 110 °C (228 to 230 °F)1.00infobox
DesogestrelMetabolismLiver, intestines (5α- and 5β-reductase, cytochrome P450 enzymes, others)1.00infobox
DesogestrelMetabolites• Etonogestrel • Others1.00infobox
DesogestrelMolar mass310.481 g·mol−11.00infobox
DesogestrelOther namesDSG; ORG-2969; 3-Deketo-11-methylene-17α-ethynyl-18-methyl-19-nortestosterone; 11-Methylene-17α-ethynyl-18-methylestr-4-en-17β-ol1.00infobox
DesogestrelProtein bindingDesogestrel: 99%: • Albumin: 99% Etonogestrel: 95–98%: • Albumin: 65–66% • SHBGTooltip sex hormone-binding globulin: 30–32% • Free: 2–5%1.00infobox
DesogestrelPubChem CID409731.00infobox
DesogestrelRoutes of administrationBy mouth1.00infobox
DesogestrelTrade namesCerazette, Lovima, Hana, others1.00infobox

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