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Clarithromycin: History, Applications & Research

Clarithromycin, sold under the brand name Biaxin among others, is an antibiotic used to treat various bacterial infections. This includes strep throat, pneumonia, skin infections, H. pylori infection, and Lyme disease. Clarithromycin can be taken by mouth as a tablet or liquid or can be infused intravenously.

Language: English [EN]
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Clarithromycin topic overview

The analysis highlights History, Applications and Research as prominent areas in the source structure around Clarithromycin.

Related topics
115
Source areas
8
Connected nodes
123
Extracted relationships
127
Concept neighborhoods
21
Bridge connections
123

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Overview · 32 topics
Contraindications · 18 topics
Side effects · 17 topics
Interactions · 16 topics
Pharmacology · 11 topics
Medical uses · 9 topics
Research · 9 topics
History · 3 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

3D model (JSmol)
Interactive image
AHFS/Drugs.com
Monograph
ATC code
J01FA09 (WHO)
Bioavailability
50%
CAS Number
81103-11-9 Y
ChEMBL
ChEMBL1741 N

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Medical uses

Contraindications

Side effects

Interactions

Pharmacology

History

Research

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How Clarithromycin connects Entity context

The extracted context around Clarithromycin shows recurring relationship patterns in the source. For example, Clarithromycin → Biaxin, Clacee, Clacid, Clarac, Clarem, Claridar, Clarihexal, Claripen, Claritron, Claritt, Clariwin, Cloff, Crixan, Fromilid, Infex, Kalixocin, Karicin, Klabax, Klacid, Klaram Another extracted example is Clarithromycin → Abbott, Abbott Laboratories, American, Biaxin, Clarith, Europe, FDA, In, Japanese, October, Taisho, Taisho Pharmaceutical, The, US. Use these groups to spot repeated connection types before inspecting the individual relationships.

Clarithromycin

Top relations

related to Brand names · 30
Clarithromycin → Biaxin, Clacee, Clacid, Clarac, Clarem, Claridar, Clarihexal, Claripen, Claritron, Claritt, Clariwin, Cloff, Crixan, Fromilid, Infex, Kalixocin, Karicin, Klabax, Klacid, Klaram
related to history · 14
Clarithromycin → Abbott, Abbott Laboratories, American, Biaxin, Clarith, Europe, FDA, In, Japanese, October, Taisho, Taisho Pharmaceutical, The, US
related to Cardiac · 7
Clarithromycin → Drug Administration, FDA, In, In February, QT, QT-prolonging, US Food
Legal status · 5
Clarithromycin → AU: S4 (Prescription only), CA: ℞-only, EU: Rx-only, In general: ℞ (Prescription only), US: ℞-only
related to Antibiotic · 5
Clarithromycin → Bartonella, Helicobacter, It, Lyme, Other
related to Contraindications · 5
Clarithromycin → Concomitant, Hypersensitivity, It, QT, Use
related to Pharmacokinetics · 5
Clarithromycin → Due, During, Highest, It, Unlike
related to Idiopathic hypersomnia · 4
Clarithromycin → Cochrane, IH, Sleep Medicine's, The American Academy
related to Calcium channel blockers · 3
Clarithromycin → Administration, Concurrent, CYP3A4
related to Colchicine · 3
Clarithromycin → Combining, CYP3A4, P-glycoprotein

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

liver drug bacterial used may effects antibiotic use citation disease side erythromycin needed include cause infections medications available pregnancy nausea

Clarithromycin relationships Subject–Predicate–Object triples

TTTA extracted 127 structured relationships around Clarithromycin. Examples in this analysis include Clarithromycin → 3D model (JSmol) → Interactive image and Clarithromycin → AHFS/Drugs.com → Monograph. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
Clarithromycin3D model (JSmol)Interactive image1.00infobox
ClarithromycinAHFS/Drugs.comMonograph1.00infobox
ClarithromycinATC codeJ01FA09 (WHO)1.00infobox
ClarithromycinBioavailability50%1.00infobox
ClarithromycinCAS Number81103-11-9 Y1.00infobox
ClarithromycinChEMBLChEMBL1741 N1.00infobox
ClarithromycinChemSpider10342604 N1.00infobox
ClarithromycinCompTox Dashboard (EPA)DTXSID30228291.00infobox
ClarithromycinDrug classMacrolides1.00infobox
ClarithromycinDrugBankDB01211 Y1.00infobox
ClarithromycinECHA InfoCard100.119.6441.00infobox
ClarithromycinElimination half-life3–4 h1.00infobox
ClarithromycinFormulaC38H69NO131.00infobox
ClarithromycinKEGGD00276 Y1.00infobox
ClarithromycinLegal statusAU: S4 (Prescription only)1.00infobox
ClarithromycinLegal statusCA: ℞-only1.00infobox
ClarithromycinLegal statusUS: ℞-only1.00infobox
ClarithromycinLegal statusEU: Rx-only1.00infobox
ClarithromycinLegal statusIn general: ℞ (Prescription only)1.00infobox
ClarithromycinLicense dataUS DailyMed: Clarithromycin1.00infobox
ClarithromycinMedlinePlusa6920051.00infobox
ClarithromycinMetabolismLiver1.00infobox
ClarithromycinMolar mass747.964 g·mol−11.00infobox
ClarithromycinOther names6-O-Methylerythromycin A1.00infobox
ClarithromycinPregnancy categoryAU: B31.00infobox
ClarithromycinProtein bindingLow binding1.00infobox
ClarithromycinPubChem CID840291.00infobox
ClarithromycinRoutes of administrationBy mouth, intravenous1.00infobox
ClarithromycinTrade namesBiaxin, Klav, etc.1.00infobox
ClarithromycinUNIIH1250JIK0A1.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around Clarithromycin bring nearby vocabulary together. In this analysis, examples include Needed, Citation and Used. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • Clarithromycin
    • Needed
    • Citation
    • Used
    • Drug
    • Liver
    • Available
    • Metabolism
    • Risk
    • Bacterial
    • Use
    • Cyp3a4
    • Idiopathic
  • clarithromycin
    • Needed
    • Citation
    • Used
    • Drug
    • Liver
    • Available
    • Metabolism
    • Risk
    • Bacterial
    • Use
    • Cyp3a4
    • Idiopathic
  • antibiotic
    • Bacterial
    • Biaxin
    • Therapy
    • Side
    • Needed
    • Citation
    • Effects
    • Used
    • Names
    • Clarithromycin
    • Cardiac
    • Colchicine
  • bacterial
    • Used
    • Names
    • Biaxin
    • Class
    • Pregnancy
    • Also
    • Infections
    • Metabolism
    • Needed
    • Citation
    • Liver
    • Clarithromycin
  • bacterial endocarditis
    • Used
    • Names
    • Biaxin
    • Class
    • Pregnancy
    • Also
    • Infections
    • Metabolism
    • Needed
    • Citation
    • Liver
    • Clarithromycin
  • chronic kidney disease
    • Liver
    • Cardiac
    • Infections
    • Kidney
    • Risk
    • May
    • Use
    • Names
    • Cyp3a4
    • Pregnancy
    • Therapy
    • Drugs
  • side effects
    • Side
    • Nausea
    • Include
    • Hypersomnia
    • Erythromycin
    • Names
    • Cardiac
    • Class
    • Colchicine
    • Idiopathic
    • Pregnancy
    • Available
  • food and drug administration
    • Names
    • Cyp3a4
    • Generic
    • Including
    • Risk
    • May
    • Class
    • Pregnancy
    • Therapy
    • Drugs
    • Infections
    • Kidney

Connections between topic areas Semantic bridges

For Clarithromycin, one of the stronger structural bridges in this analysis connects Clarithromycin with Overview. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
Clarithromycin — Overview · splits 91 ⟂ 33
Clarithromycin — Contraindications · splits 105 ⟂ 19
Clarithromycin — Side effects · splits 106 ⟂ 18
Clarithromycin — Interactions · splits 107 ⟂ 17
Clarithromycin — Pharmacology · splits 112 ⟂ 12
Clarithromycin — Medical uses · splits 114 ⟂ 10
Clarithromycin — Research · splits 114 ⟂ 10
Clarithromycin — History · splits 120 ⟂ 4

Map overview Semantic statistics

Clarithromycin

Nodes124
Edges123
Triples127
Avg. degree1.98
Density0.016129
Components1

Source & methodology

TTTA analyzes the structure around Clarithromycin to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as History, Applications & Research, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — Clarithromycin · EN edition · Analysis: TopicsToTalkAbout

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