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Boceprevir

Boceprevir (INN, trade name Victrelis) is a protease inhibitor used to treat hepatitis caused by hepatitis C virus (HCV) genotype 1. It binds to the HCV nonstructural protein 3 active site.

Clinical trials & Overview

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Explore the main themes, entities and connections around Boceprevir. Start with the topic map, then use the sections below for research and deeper semantic analysis.

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Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

3D model (JSmol)
Interactive image
AHFS/Drugs.com
Consumer Drug Information
ATC code
J05AP03 (WHO)
CAS Number
394730-60-0 Y
ChEMBL
ChEMBL218394 Y
ChemSpider
8499830 Y

Topics to explore

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Overview

Clinical trials

Advanced semantic analysis

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Map overview Semantic statistics

Boceprevir

Nodes19
Edges18
Triples49
Avg. degree1.89
Density0.105263
Components1

How this topic connects Entity context

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Boceprevir

Top relations

related to SPRINT-1 trial · 11
Boceprevir → April, Copenhagen, European Association, HCV, II, Liver, Study, SVR, The, The SPRINT-1, When
related to SPRINT-2 trial · 8
Boceprevir → At, Black, Each, HCV RNA, Important, In, The, The SPRINT-2
related to RESPOND-2 trial · 6
Boceprevir → All, At, Four, HCV RNA, The, The RESPOND-2
License data · 2
Boceprevir → EU EMA: by INN, US FDA: Boceprevir
3D model (JSmol) · 1
Boceprevir → Interactive image
AHFS/Drugs.com · 1
Boceprevir → Consumer Drug Information
ATC code · 1
Boceprevir → J05AP03 (WHO)
CAS Number · 1
Boceprevir → 394730-60-0 Y
ChEMBL · 1
Boceprevir → ChEMBL218394 Y
ChemSpider · 1
Boceprevir → 8499830 Y

Important terminology Word statistics

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Important terminology

patients weeks peginterferon ribavirin citation needed plus therapy group received hcv trial 44 genotype victrelis study alfa-2b three peginterferon-ribavirin hepatitis

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Boceprevir3D model (JSmol)Interactive image1.00infobox
BoceprevirAHFS/Drugs.comConsumer Drug Information1.00infobox
BoceprevirATC codeJ05AP03 (WHO)1.00infobox
BoceprevirCAS Number394730-60-0 Y1.00infobox
BoceprevirChEMBLChEMBL218394 Y1.00infobox
BoceprevirChemSpider8499830 Y1.00infobox
BoceprevirCompTox Dashboard (EPA)DTXSID309601031.00infobox
BoceprevirDrugBankDB08873 Y1.00infobox
BoceprevirECHA InfoCard100.226.2461.00infobox
BoceprevirElimination half-life3.4 hours1.00infobox
BoceprevirFormulaC27H45N5O51.00infobox
BoceprevirIUPHAR/BPS78761.00infobox
BoceprevirKEGGD08876 Y1.00infobox
BoceprevirLegal statusUS: ℞-only1.00infobox
BoceprevirLicense dataEU EMA: by INN1.00infobox
BoceprevirLicense dataUS FDA: Boceprevir1.00infobox
BoceprevirMedlinePlusa6110391.00infobox
BoceprevirMolar mass519.687 g·mol−11.00infobox
BoceprevirNIAID ChemDB3984931.00infobox
BoceprevirProtein binding75%1.00infobox
BoceprevirPubChem CID103243671.00infobox
BoceprevirRoutes of administrationOral1.00infobox
BoceprevirTrade namesVictrelis1.00infobox
BoceprevirUNII89BT58KELH1.00infobox

Related concept clusters Concept neighborhoods

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