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Boceprevir: Clinical trials & Overview

Boceprevir (INN, trade name Victrelis) is a protease inhibitor used to treat hepatitis caused by hepatitis C virus (HCV) genotype 1. It binds to the HCV nonstructural protein 3 active site.

Language: English [EN]
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Boceprevir topic overview

The analysis highlights Clinical trials and Overview as prominent areas in the source structure around Boceprevir.

Related topics
16
Source areas
2
Connected nodes
18
Extracted relationships
49
Concept neighborhoods
10
Bridge connections
18

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Clinical trials · 8 topics
Overview · 8 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

3D model (JSmol)
Interactive image
AHFS/Drugs.com
Consumer Drug Information
ATC code
J05AP03 (WHO)
CAS Number
394730-60-0 Y
ChEMBL
ChEMBL218394 Y
ChemSpider
8499830 Y

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Clinical trials

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How Boceprevir connects Entity context

The extracted context around Boceprevir shows recurring relationship patterns in the source. For example, Boceprevir → April, Copenhagen, European Association, HCV, II, Liver, Study, SVR, The, The SPRINT-1, When Another extracted example is Boceprevir → At, Black, Each, HCV RNA, Important, In, The, The SPRINT-2. Use these groups to spot repeated connection types before inspecting the individual relationships.

Boceprevir

Top relations

related to SPRINT-1 trial · 11
Boceprevir → April, Copenhagen, European Association, HCV, II, Liver, Study, SVR, The, The SPRINT-1, When
related to SPRINT-2 trial · 8
Boceprevir → At, Black, Each, HCV RNA, Important, In, The, The SPRINT-2
related to RESPOND-2 trial · 6
Boceprevir → All, At, Four, HCV RNA, The, The RESPOND-2
License data · 2
Boceprevir → EU EMA: by INN, US FDA: Boceprevir
3D model (JSmol) · 1
Boceprevir → Interactive image
AHFS/Drugs.com · 1
Boceprevir → Consumer Drug Information
ATC code · 1
Boceprevir → J05AP03 (WHO)
CAS Number · 1
Boceprevir → 394730-60-0 Y
ChEMBL · 1
Boceprevir → ChEMBL218394 Y
ChemSpider · 1
Boceprevir → 8499830 Y

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

patients weeks peginterferon ribavirin citation needed plus therapy group received hcv trial 44 genotype victrelis study alfa-2b three peginterferon-ribavirin hepatitis

Boceprevir relationships Subject–Predicate–Object triples

TTTA extracted 49 structured relationships around Boceprevir. Examples in this analysis include Boceprevir → 3D model (JSmol) → Interactive image and Boceprevir → AHFS/Drugs.com → Consumer Drug Information. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
Boceprevir3D model (JSmol)Interactive image1.00infobox
BoceprevirAHFS/Drugs.comConsumer Drug Information1.00infobox
BoceprevirATC codeJ05AP03 (WHO)1.00infobox
BoceprevirCAS Number394730-60-0 Y1.00infobox
BoceprevirChEMBLChEMBL218394 Y1.00infobox
BoceprevirChemSpider8499830 Y1.00infobox
BoceprevirCompTox Dashboard (EPA)DTXSID309601031.00infobox
BoceprevirDrugBankDB08873 Y1.00infobox
BoceprevirECHA InfoCard100.226.2461.00infobox
BoceprevirElimination half-life3.4 hours1.00infobox
BoceprevirFormulaC27H45N5O51.00infobox
BoceprevirIUPHAR/BPS78761.00infobox
BoceprevirKEGGD08876 Y1.00infobox
BoceprevirLegal statusUS: ℞-only1.00infobox
BoceprevirLicense dataEU EMA: by INN1.00infobox
BoceprevirLicense dataUS FDA: Boceprevir1.00infobox
BoceprevirMedlinePlusa6110391.00infobox
BoceprevirMolar mass519.687 g·mol−11.00infobox
BoceprevirNIAID ChemDB3984931.00infobox
BoceprevirProtein binding75%1.00infobox
BoceprevirPubChem CID103243671.00infobox
BoceprevirRoutes of administrationOral1.00infobox
BoceprevirTrade namesVictrelis1.00infobox
BoceprevirUNII89BT58KELH1.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around Boceprevir bring nearby vocabulary together. In this analysis, examples include Weeks, Citation and Group. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • Boceprevir
    • Weeks
    • Citation
    • Group
    • Needed
    • Plus
    • Therapy
    • Hcv
    • Patients
    • Received
    • Four
    • Svr
    • Third
  • boceprevir
    • Weeks
    • Citation
    • Group
    • Needed
    • Plus
    • Therapy
    • Hcv
    • Patients
    • Received
    • Four
    • Svr
    • Third
  • peginterferon alfa-2b
    • Ribavirin
    • Peginterferon
    • Plus
    • Three
    • Four
    • One
    • Patients
    • Received
    • Svr
    • Therapy
    • Enrolled
    • Study
  • hepatitis c virus
    • Genotype
    • Response
    • Sustained
    • Trial
    • Citation
    • Needed
    • Therapy
    • Inn
    • Name
    • Trade
    • Viral
    • One
  • peginterferon
    • Ribavirin
    • Plus
    • Three
    • Received
    • Therapy
    • Enrolled
    • Four
    • One
    • Svr
    • Study
    • Citation
    • Group
  • ribavirin
    • Plus
    • Three
    • Received
    • Therapy
    • One
    • Svr
    • Study
    • Group
    • Weeks
    • Sprint-1
    • Viral
    • Third
  • inn
    • Name
    • Trade
    • Victrelis
    • Genotype
    • Hcv
    • Difficult-to-treat
    • Fda
    • Protein
    • Sprint-1
    • Hepatitis
    • Trial
    • Patients
  • fda
    • Difficult-to-treat
    • Inn
    • Name
    • Protein
    • Sprint-1
    • Trade
    • Victrelis
    • Genotype
    • Hcv
    • Trial
    • Patients

Connections between topic areas Semantic bridges

For Boceprevir, one of the stronger structural bridges in this analysis connects Boceprevir with Overview. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
BoceprevirOverview · splits 10 ⟂ 9
BoceprevirClinical trials · splits 10 ⟂ 9

Map overview Semantic statistics

Boceprevir

Nodes19
Edges18
Triples49
Avg. degree1.89
Density0.105263
Components1

Source & methodology

TTTA analyzes the structure around Boceprevir to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Clinical trials & Overview, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — Boceprevir · EN edition · Analysis: TopicsToTalkAbout

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