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Telaprevir: Research & Standards

Telaprevir (VX-950), was marketed under the brand names Incivek and Incivo, is a pharmaceutical drug for the treatment of hepatitis C co-developed by Vertex Pharmaceuticals and Johnson & Johnson. It is a member of a class of antiviral drugs known as protease inhibitors. Specifically, telaprevir inhibits the hepatitis C viral enzyme NS3/4A serine…

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Telaprevir topic overview

The analysis highlights Research and Standards as prominent areas in the source structure around Telaprevir.

Related topics
22
Source areas
4
Connected nodes
26
Extracted relationships
61
Concept neighborhoods
14
Bridge connections
26

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Overview · 9 topics
Clinical trials and approvals · 7 topics
Adverse effects · 4 topics
Research · 2 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

3D model (JSmol)
Interactive image
AHFS/Drugs.com
Consumer Drug Information
ATC code
J05AP02 (WHO)
CAS Number
402957-28-2 N
ChEBI
CHEBI:68595 N
ChEMBL
ChEMBL231813 Y

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Clinical trials and approvals

Adverse effects

Research

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How Telaprevir connects Entity context

The extracted context around Telaprevir shows recurring relationship patterns in the source. For example, Telaprevir → ADVANCE, Committee, FDA Antiviral Drugs Advisory, HCV, III ADVANCE, ILLUMINATE, In, May, Merck's, On April, PROVE3, REALIZE, SVR, The, This, United States Another extracted example is Telaprevir → After, Drug Administration, FDA, Grade, Incivek, On December, The, The FDA, US, US Food, Vertex. Use these groups to spot repeated connection types before inspecting the individual relationships.

Telaprevir

Top relations

related to Clinical trials and approvals · 16
Telaprevir → ADVANCE, Committee, FDA Antiviral Drugs Advisory, HCV, III ADVANCE, ILLUMINATE, In, May, Merck's, On April, PROVE3, REALIZE, SVR, The, This, United States
has effect · 11
Telaprevir → After, Drug Administration, FDA, Grade, Incivek, On December, The, The FDA, US, US Food, Vertex
related to Availability · 4
Telaprevir → Incivek, On August, The, Vertex Pharmaceuticals
related to Research · 4
Telaprevir → AFM, D68, Since, Studies
3D model (JSmol) · 1
Telaprevir → Interactive image
AHFS/Drugs.com · 1
Telaprevir → Consumer Drug Information
ATC code · 1
Telaprevir → J05AP02 (WHO)
CAS Number · 1
Telaprevir → 402957-28-2 N
ChEBI · 1
Telaprevir → CHEBI:68595 N
ChEMBL · 1
Telaprevir → ChEMBL231813 Y

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

hepatitis svr therapy ribavirin patients treatment genotype incivek drug vertex viral fda drugs trial peginterferon response antiviral use standard protease

Telaprevir relationships Subject–Predicate–Object triples

TTTA extracted 61 structured relationships around Telaprevir. Examples in this analysis include Telaprevir → 3D model (JSmol) → Interactive image and Telaprevir → AHFS/Drugs.com → Consumer Drug Information. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
Telaprevir3D model (JSmol)Interactive image1.00infobox
TelaprevirAHFS/Drugs.comConsumer Drug Information1.00infobox
TelaprevirATC codeJ05AP02 (WHO)1.00infobox
TelaprevirCAS Number402957-28-2 N1.00infobox
TelaprevirChEBICHEBI:68595 N1.00infobox
TelaprevirChEMBLChEMBL231813 Y1.00infobox
TelaprevirChemSpider2279948 Y1.00infobox
TelaprevirCompTox Dashboard (EPA)DTXSID401933041.00infobox
TelaprevirDrugBankDB05521 N1.00infobox
TelaprevirECHA InfoCard100.129.8571.00infobox
TelaprevirElimination half-life9–11 hours1.00infobox
TelaprevirExcretion90% (bile), 9% (exhaled air), 1% (urine)1.00infobox
TelaprevirFormulaC36H53N7O61.00infobox
TelaprevirIUPHAR/BPS78711.00infobox
TelaprevirKEGGD09012 Y1.00infobox
TelaprevirLegal statusUS: ℞-only1.00infobox
TelaprevirLicense dataUS FDA: Telaprevir1.00infobox
TelaprevirMedlinePlusa6110381.00infobox
TelaprevirMetabolismextensive hepatic1.00infobox
TelaprevirMolar mass679.863 g·mol−11.00infobox
TelaprevirNIAID ChemDB2130061.00infobox
TelaprevirProtein binding59–76%1.00infobox
TelaprevirPubChem CID30108181.00infobox
TelaprevirRoutes of administrationOral1.00infobox
TelaprevirTrade namesIncivek, Incivo1.00infobox
TelaprevirUNII655M5O3W0U1.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around Telaprevir bring nearby vocabulary together. In this analysis, examples include Hepatitis, Ribavirin and Treatment. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • Telaprevir
    • Hepatitis
    • Ribavirin
    • Treatment
    • Patients
    • Svr
    • Fda
    • Peginterferon
    • Trial
    • Vertex
    • Alfa-2a
    • Standard
    • Us
  • telaprevir
    • Hepatitis
    • Ribavirin
    • Treatment
    • Patients
    • Svr
    • Fda
    • Peginterferon
    • Trial
    • Vertex
    • Alfa-2a
    • Standard
    • Us
  • hepatitis c
    • Telaprevir
    • Vertex
    • Viral
    • Incivek
    • Treatment
    • Therapy
    • Pharmaceuticals
    • Virus
    • Sustained
    • Use
    • Drugs
    • Fda
  • antiviral drugs
    • Fda
    • Drugs
    • Us
    • Peginterferon
    • Incivek
    • Protease
    • Ribavirin
    • Treatment
    • Patients
    • Committee
    • Incivo
    • Names
  • fda
    • Us
    • Incivek
    • Treatment
    • People
    • Patients
    • Peginterferon
    • Vertex
    • Ribavirin
    • Telaprevir
    • Incivo
    • Names
    • Alfa-2a
  • adverse effects
    • Incivo
    • Names
    • Virus
    • Alfa-2a
    • Standard
    • Sustained
    • Us
    • Drugs
    • Fda
    • Peginterferon
    • Response
    • Trial
  • peginterferon alfa-2a
    • Alfa-2a
    • Peginterferon
    • Ribavirin
    • Treatment
    • Us
    • Svr
    • Incivo
    • Names
    • Patients
    • Telaprevir
    • Standard
    • Sustained
  • vertex pharmaceuticals
    • Incivek
    • Brand
    • Drug
    • Pharmaceuticals
    • Vertex
    • Treatment
    • Us
    • Fda
    • Hepatitis
    • Patients
    • Telaprevir
    • Incivo

Connections between topic areas Semantic bridges

For Telaprevir, one of the stronger structural bridges in this analysis connects Telaprevir with Overview. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
TelaprevirOverview · splits 17 ⟂ 10
TelaprevirClinical trials and approvals · splits 19 ⟂ 8
TelaprevirAdverse effects · splits 22 ⟂ 5
TelaprevirResearch · splits 24 ⟂ 3

Map overview Semantic statistics

Telaprevir

Nodes27
Edges26
Triples61
Avg. degree1.93
Density0.074074
Components1

Source & methodology

TTTA analyzes the structure around Telaprevir to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Research & Standards, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — Telaprevir · EN edition · Analysis: TopicsToTalkAbout

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